Concurrent chemoradiotherapy for esophageal carcinoma patients with malignant fistulae

Muto, Manabu; Ohtsu, Atsushi; Miyamoto, Shin’ichi; Muro, Kei; Boku, Narikazu; Ishikura, Satoshi; Satake, Mitsuo; Ogino, Takashi; Tajiri, Hisao; Yoshida, Shigeaki

doi:10.1002/(sici)1097-0142(19991015)86:8<1406::aid-cncr4>3.0.co;2-3

Cited by 45 publications

(26 citation statements)

References 24 publications

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“…enables restoration of the perforated mucosa and connective tissues, and it therefore seems that treatment for the cause of the fistula should come before protection of the fistula. This theory is supported by the course of the present case and the course of a previously reported case [7] .…”

Section: Possibility Of Closure Of a Fistulasupporting

confidence: 91%

“…Propriety o�� treatment ��or esophageal malignancy with a fistula It has been reported that continuing and completing a course of treatment for malignancy seems to be better than suspending treatment even if a malignant fistula appears in the course of treatment [1,2,7] . However, there has been no report on the size limit of a treatable fistula and the propriety of treatment with the presence of a giant fistula.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies, however, have suggested that bypass surgery and radiotherapy may be more effective than other treatments [1,2,[7][8][9][10] . In radiotherapy for advanced esophageal malignancies, continuation and completion of the radiotherapy is important regardless of fistula formation [1,7] .…”

Section: Introductionmentioning

confidence: 99%

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Chemoradiotherapy for a patient with a giant esophageal fistula

Nomiya

Teruyama²,

Wada³

et al. 2007

WJG

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Section: Possibility Of Closure Of a Fistulasupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

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Chemoradiotherapy for a patient with a giant esophageal fistula

Nomiya

Teruyama²,

Wada³

et al. 2007

WJG

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“…Recently, there have been reports that radiotherapy and chemotherapy contributed to fistula closure and improved patient survival. 7,8 Burstow et al 9 reported that patients (n 5 23) receiving adjuvant chemotherapy or radiotherapy, in addition to stenting, survived significantly longer than those (n 5 67) who received a stent alone (mean survival, 152.8 days versus 71.8 days). In the present cases, stent placement could not be performed because of severe esophageal stenosis.…”

Section: Discussionmentioning

confidence: 99%

Esophageal Bypass Using a Gastric Tube for a Malignant Tracheoesophageal/Bronchoesophageal Fistula: A Report of 4 Cases

Hanagiri

Morita

Shigematsu

et al. 2011

International Surgery

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Tracheoesophageal/bronchoesophageal fistulas are often caused by locally advanced esophageal cancer and lung cancer, and result in life-threatening conditions such as severe cough and dyspnea due to pneumonia. We herein report the clinical characteristics of 4 patients with tracheoesophageal/bronchoesophageal fistulas. All patients were men, and ranged in age from 40–69 years. Three patients had esophageal cancer and 1 had lung cancer. All 4 underwent esophageal bypass using a gastric tube with tube drainage of the distal side of the esophagus. Three patients died at 3, 4, and 5 months after surgery. However, these patients were allowed to enjoy food orally up until the last few days of life. One patient who underwent esophageal bypass and chemoradiotherapy has remained well for 5 years without any evidence of recurrence. This bypass procedure is therefore considered to be a feasible treatment choice for patients with tracheoesophageal/bronchoesophageal fistulas.

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“…Two had their chemoradiotherapy interrupted because of pneumonia. One of the 2 received additional chemotherapy after successful treatment of pneumonia: the other died of perforation of the aorta [16].…”

Section: Discussionmentioning

confidence: 99%