Chemoradiotherapy for a patient with a giant esophageal fistula

Nomiya, Takuma; Teruyama, Kazuhide; Wada, Hitoshi; Nemoto, Kenji

doi:10.3748/wjg.v13.i15.2250

Cited by 4 publications

(5 citation statements)

References 13 publications

(15 reference statements)

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“…However, in this case, the aortic prosthetic graft infection had been accompanied with esophagomediastinal fistulas but had not perforated, so the patient recovered after medical treatment and three operations. Although cases of esophagomediastinal fistulas due to esophageal cancer [8], esophageal tuberculosis [9], endoscopic ultrasound-guided fine-needle aspiration [10], or esophageal diverticulum [11] have been reported, as far as we know no cases caused by vascular surgery have ever been reported. It is difficult to confirm how the patient's esophagomediastinal fistulas formed.…”

Section: Discussionmentioning

confidence: 99%

Aortic prosthetic graft infection accompanied with esophagomediastinal fistulas: A case report

Amano

Azuma

Izumi

et al. 2012

Journal of Cardiology Cases

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Prosthetic graft infection is difficult to diagnose early, and hence, is associated with high mortality and morbidity rates. A 63-year-old man who had undergone surgical prosthetic replacement for an inflammatory thoracic aortic aneurysm 10 months previously visited our emergency room, complaining of chills, shivering, frequent vomiting, and back pain. He was diagnosed with severe sepsis, and a blood culture detected Streptococcus anginosus and Prevotella oralis. Repeated contrast-enhanced computed tomography (CT) scans of his chest revealed ectopic gas around the graft, and esophagogastroduodenoscopy revealed esophageal perforations at several sites. We therefore diagnosed him with aortic prosthetic graft infection accompanied with esophagomediastinal fistulas. He received medical treatment and three operations and recovered from the infection. This is a rare case of aortic prosthetic graft infection accompanied with esophagomediastinal fistulas, and we conclude that repeated CT is useful for identifying the primary infection site and invasion route in patients with suspected aortic prosthetic graft infection.

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Section: Discussionmentioning

confidence: 99%

Aortic prosthetic graft infection accompanied with esophagomediastinal fistulas: A case report

Amano

Azuma

Izumi

et al. 2012

Journal of Cardiology Cases

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“…This surgical technique was implemented in 2 patients, in which one case required the same procedure twice due to recurrence. 12 Similarly, Mobashir et al performed a double nonresorbable suture circumferential ligation of the fistula tract to guarantee a successful closure, but his approach was through an incision of 2.5 cm above the superior tracheostomy edge to preserve the stoma integrity. 34 In his cohort, the TEP was effectively closed in 100% of patients.…”

Section: Discussionmentioning

confidence: 99%

“…1). [8][9][10]12, Using the OCEBM, 33 studies had a level of evidence of 4. No discrepancies during quality assessment occurred.…”

Section: Literature Search and Quality Assessmentmentioning

confidence: 99%

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Definitive Closure of the Tracheoesophageal Puncture Site after Oncologic Laryngectomy: A Systematic Review and Meta-Analysis

et al. 2022

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Tracheoesophageal puncture (TEP) and voice prosthesis insertion following laryngectomy may fail to form an adequate seal. When spontaneous closure of the fistula tract does not occur after conservative measures, surgical closure is required. The purpose of this study was to summarize the available evidence on surgical methods for TEP site closure.A comprehensive search across PubMed, Web of Science, SCOPUS, and Cochrane was performed to identify studies describing surgical techniques, outcomes, and complications for TEP closure. We evaluated the rate of unsuccessful TEP closure after surgical management. A meta-analysis with a random-effect method was performed.Thirty-four studies reporting on 144 patients satisfied inclusion criteria. The overall incidence of an unsuccessful TEP surgical closure was 6% (95% confidence interval [CI] 1–13%). Subgroup analysis showed an unsuccessful TEP closure rate for silicone button of 8% (95% CI < 1–43%), 7% (95% CI < 1–34%) for dermal graft interposition, < 1% (95% CI < 1–37%) for radial forearm free flap, < 1% (95% CI < 1–52%) for ligation of the fistula, 17% (95% CI < 1–64%) for interposition of a deltopectoral flap, 9% (95% CI < 1–28%) for primary closure, and 2% (95% CI < 1–20%) for interposition of a sternocleidomastoid muscle flap.Critical assessment of the reconstructive modality should take into consideration previous history of surgery or radiotherapy. Nonirradiated fields and small defects may benefit from fistula excision and tracheal and esophageal multilayer closure. In cases of previous radiotherapy, local flaps or free tissue transfer yield high successful TEP closure rates. Depending on the defect size, sternocleidomastoid muscle flap or fasciocutaneous free flaps are optimal alternatives.

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“…This phenomenon has also been observed in other normal tissue such as esophageal fistula after tumor disappearance. 17 These clinical experiences suggest that RT need not be stopped because of a skin defect. In this study, reduction of skin defect and regeneration of normal skin were observed in all patients.…”

Section: Quality Of Life and Symptomsmentioning

confidence: 99%

Modified Simultaneous Integrated Boost Radiotherapy for Unresectable Locally Advanced Breast Cancer: Preliminary Results of a Prospective Clinical Trial

Nomiya¹,

Akamatsu

Harada

et al. 2015

Clinical Breast Cancer

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Chemoradiotherapy for a patient with a giant esophageal fistula

Abstract: We describe our experience of treatment for a giant esophageal malignant fistula, which has not been reported previously. A 36-year-old woman who was diagnosed as having massive esophageal small cell carcinoma with metastases was treated with chemoradiotherapy.

Cited by 4 publications

References 13 publications

Aortic prosthetic graft infection accompanied with esophagomediastinal fistulas: A case report

Aortic prosthetic graft infection accompanied with esophagomediastinal fistulas: A case report

Definitive Closure of the Tracheoesophageal Puncture Site after Oncologic Laryngectomy: A Systematic Review and Meta-Analysis

Modified Simultaneous Integrated Boost Radiotherapy for Unresectable Locally Advanced Breast Cancer: Preliminary Results of a Prospective Clinical Trial

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