Concordancia de las escalas REGICOR y SCORE para la identificación del riesgo cardiovascular alto en la población española

Gil-Guillén, Vicente Francisco; Orozco‐Beltrán, Domingo; Maiques-Galán, Antonio; Aznar-Vicente, J.; Navarro, Jorge; Cea‐Calvo, Luis; Quirze-Andrés, Fernando; Redón, Josep; Merino-Sánchez, Jaime

doi:10.1157/13111236

Cited by 29 publications

(16 citation statements)

References 30 publications

(31 reference statements)

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“…The percentage of patients classified in this study as having a high CVR using the SCORE equation is similar to that reported by other studies in the primary care setting [19], in the general population [21], or in hypertensive individuals [30]. The D’Agostino scale classifies twice as many patients as being at high risk compared with the SCORE, and both scales classify a much larger proportion of males as presenting high risk.…”

Section: Discussionsupporting

confidence: 84%

“…The scales compared in this study measure CVR, mortality risk and morbidity-mortality risk. This is probably why agreement between the two scales shows a kappa index of 0.58, which is better than that published by other authors comparing the Framingham-REGICOR and SCORE [19,21,30], or the Framingham and SCORE [12,13,30], since these are equations that predict different cardiovascular events (coronary morbidity-mortality and cardiovascular mortality).…”

Section: Discussionmentioning

confidence: 69%

“…In studies involving subjects seen in primary care centers, the SCORE and Framingham estimate higher risk—thus indicating lipid-lowering drug treatment in a larger number of patients than the REGICOR [16,21]. The scales compared in this study measure CVR, mortality risk and morbidity-mortality risk.…”

Section: Discussionmentioning

confidence: 99%

“…The original Framingham function [10,11], in its different versions, identifies more high CVR patients than the SCORE chart [12,13]. However, its calibration for the Spanish population (REGICOR) [14,15] identifies fewer high CVR patients than the original scale [16,17], and agreement in identification of patients with high CVR [18–21] is low. It should be kept in mind that the scales derived from the Framingham function estimate the incidence of coronary disease, with the exception of the D’Agostino scale, which estimates global cardiovascular morbidity and mortality, whereas the SCORE estimates cardiovascular mortality.…”

Section: Introductionmentioning

confidence: 99%

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Agreement between the SCORE and D’Agostino Scales for the Classification of High Cardiovascular Risk in Sedentary Spanish Patients

Gómez‐Marcos¹,

Grandes²,

Iglesias-Valiente³

et al. 2009

IJERPH

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Background:To evaluate agreement between cardiovascular risk in sedentary patients as estimated by the new Framingham-D’Agostino scale and by the SCORE chart, and to describe the patient characteristics associated with the observed disagreement between the scales.Design:A cross-sectional study was undertaken involving a systematic sample of 2,295 sedentary individuals between 40–65 years of age seen for any reason in 56 primary care offices. An estimation was made of the Pearson correlation coefficient and kappa statistic for the classification of high risk subjects (≥20% according to the Framingham-D’Agostino scale, and ≥5% according to SCORE). Polytomous logistic regression models were fitted to identify the variables associated with the discordance between the two scales.Results:The mean risk in males (35%) was 19.5% ± 13% with D’Agostino scale, and 3.2% ± 3.3% with SCORE. Among females, they were 8.1% ± 6.8% and 1.2% ± 2.2%, respectively. The correlation between the two scales was 0.874 in males (95% CI: 0.857–0.889) and 0.818 in females (95% CI: 0.800–0.834), while the kappa index was 0.50 in males (95% CI: 0.44%–0.56%) and 0.61 in females (95% CI: 0.52%–0.71%). The most frequent disagreement, characterized by high risk according to D’Agostino scale but not according to SCORE, was much more prevalent among males and proved more probable with increasing age and increased LDL-cholesterol, triglyceride and systolic blood pressure values, as well as among those who used antihypertensive drugs and smokers.Conclusions:The quantitative correlation between the two scales is very high. Patient categorization as corresponding to high risk generates disagreements, mainly among males, where agreement between the two classifications is only moderate.

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Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Agreement between the SCORE and D’Agostino Scales for the Classification of High Cardiovascular Risk in Sedentary Spanish Patients

Gómez‐Marcos¹,

Grandes²,

Iglesias-Valiente³

et al. 2009

IJERPH

View full text Add to dashboard Cite

show abstract

“…Of note, although the relative risk is always higher in high‐risk persons, most CVD events (55–80%) occur in the low and moderate risk strata,10, 13 a major problem for a personalized risk reduction approach considering that usually >75% of the population is classified as non–high risk 14, 15. Consequently, the usefulness of these tools in different settings and populations and its CVD predictive ability are still a matter of debate 16…”

Section: Introductionmentioning

confidence: 99%

Prediction of Cardiovascular Disease by the Framingham‐REGICOR Equation in the High‐Risk PREDIMED Cohort: Impact of the Mediterranean Diet Across Different Risk Strata

Amor

Serra‐Mir

Martínez‐González

et al. 2017

JAHA

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BackgroundThe usefulness of cardiovascular disease (CVD) predictive equations in different populations is debatable. We assessed the efficacy of the Framingham‐REGICOR scale, validated for the Spanish population, to identify future CVD in participants, who were predefined as being at high‐risk in the PREvención con DIeta MEDiterránea (PREDIMED) study—a nutrition‐intervention primary prevention trial—and the impact of adherence to the Mediterranean diet on CVD across risk categories.Methods and ResultsIn a post hoc analysis, we assessed the CVD predictive value of baseline estimated risk in 5966 PREDIMED participants (aged 55–74 years, 57% women; 48% with type 2 diabetes mellitus). Major CVD events, the primary PREDIMED end point, were an aggregate of myocardial infarction, stroke, and cardiovascular death. Multivariate‐adjusted Cox regression was used to calculate hazard ratios for major CVD events and effect modification from the Mediterranean diet intervention across risk strata (low, moderate, high, very high). The Framingham‐REGICOR classification of PREDIMED participants was 25.1% low risk, 44.5% moderate risk, and 30.4% high or very high risk. During 6‐year follow‐up, 188 major CVD events occurred. Hazard ratios for major CVD events increased in parallel with estimated risk (2.68, 4.24, and 6.60 for moderate, high, and very high risk), particularly in men (7.60, 13.16, and 15.85, respectively, versus 2.16, 2.28, and 3.51, respectively, in women). Yet among those with low or moderate risk, 32.2% and 74.3% of major CVD events occurred in men and women, respectively. Mediterranean diet adherence was associated with CVD risk reduction regardless of risk strata (P>0.4 for interaction).ConclusionsIncident CVD increased in parallel with estimated risk in the PREDIMED cohort, but most events occurred in non–high‐risk categories, particularly in women. Until predictive tools are improved, promotion of the Mediterranean diet might be useful to reduce CVD independent of baseline risk.Clinical Trial Registration URL: http://www.Controlled-trials.com. Unique identifier: ISRCTN35739639.

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Psoriasis: una enfermedad cutánea relacionada con riesgo cardiovascular elevado

González-Vela

González‐Juanatey

2012

Actas Dermo-Sifiliográficas

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Concordancia de las escalas REGICOR y SCORE para la identificación del riesgo cardiovascular alto en la población española

Cited by 29 publications

References 30 publications

Agreement between the SCORE and D’Agostino Scales for the Classification of High Cardiovascular Risk in Sedentary Spanish Patients

Agreement between the SCORE and D’Agostino Scales for the Classification of High Cardiovascular Risk in Sedentary Spanish Patients

Prediction of Cardiovascular Disease by the Framingham‐REGICOR Equation in the High‐Risk PREDIMED Cohort: Impact of the Mediterranean Diet Across Different Risk Strata

Psoriasis: una enfermedad cutánea relacionada con riesgo cardiovascular elevado

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