Concomitant obstructive sleep apnea increases the recurrence of atrial fibrillation following radiofrequency catheter ablation of atrial fibrillation: Clinical impact of continuous positive airway pressure therapy

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

“…Obturacyjny bezdech senny nasila zmiany ciśnienia wewnątrz klatki piersiowej, które same oraz za pośrednictwem aktywacji nerwu błędnego mogą prowadzić do skrócenia potencjału czynnościowego w przedsionkach i wywoływać AF. Redukcja czynników ryzyka oraz wentylacja z ciągłym dodatnim ciśnieniem w drogach oddechowych mogą ograniczać nawroty AF [308][309][310][311][312]. Wydaje się rozsąd-nym rozważanie przesiewowego wykrywania obturacyjnego bezdechu sennego u pacjentów z AF i obciążonych czynnikami ryzyka.…”

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

“…283,289,290,291,316,317,318,319 Although OSA has been associated with poorer outcomes, CPAP appears to attenuate the deleterious impact of OSA. Pooled analysis suggests that although OSA increases the risk of AF recurrence following ablation (RR 1.31; 95% CI 1.16–1.48; P <.001), CPAP therapy improves ablation success to rates comparable with non-OSA populations (RR 1.25; 95% CI 0.77–2.03; P = .37).…”

The Clinical Profile and Pathophysiology of Atrial Fibrillation

“…[53][54][55][56][57][58][59] Although it remains unclear whether OSA is independently and pathogenetically linked to AF or merely reflects a shared risk factor profile, the observation that continuous positive pressure ventilation reduces the risk of recurrent AF supports a causal role of OSA in AF pathogenesis. 53,55,56,59 Chronic Kidney Disease AF is more prevalent in patients with chronic renal dysfunction, even after accounting for associated factors (coronary heart disease, HF, hypertension, left ventricular hypertrophy, and systemic inflammation). AF risk increases with severity of renal dysfunction (eg, HR of 1.3-1.6 and 1.6-3.2 with an estimated glomerular filtration rate of 30-59 and <30 mL/min per 1.73 m 2 , respectively, versus estimated glomerular filtration rate ≥60 mL/min per 1.73 m 2 ).…”