Concomitant and controlled release of furazolidone and bismuth(III) incorporated in a cross-linked sodium alginate-carboxymethyl cellulose hydrogel

Silva, Kláudia Maria Machado Neves; Carvalho, Diogo Émerson Leite de; Valente, Vânia Maria Moreira; Rubio, Juan Carlos Campos; Faria, Paulo Eustáquio de; Silva-Caldeira, Priscila Pereira

doi:10.1016/j.ijbiomac.2018.12.136

Cited by 39 publications

(14 citation statements)

References 30 publications

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“…32 One of the antibiotic drugs that are heavily consumed and might lead to environmental pollution is furazolidone (FZD), a subclass of nitrofuran derivative drugs. 37,38 It has been extensively used in veterinary and human medicine in the treatment and prevention of microorganism as well as the food supplement for food-producing animals. 39,40 With wide applications of FZD in food-producing animals, the FZD residues were frequently found in foodstuffs.…”

Section: ■ Introductionmentioning

confidence: 99%

“…It is well documented that the continuous proliferation of antibiotic compounds can cause the occurrence of antibiotic-resistant bacteria, hormone disruption, superbugs, and antibiotic-resistant genes. − According to the WHO’s report, 10 million people die each year because of the superbugs . One of the antibiotic drugs that are heavily consumed and might lead to environmental pollution is furazolidone (FZD), a subclass of nitrofuran derivative drugs. , It has been extensively used in veterinary and human medicine in the treatment and prevention of microorganism as well as the food supplement for food-producing animals. , With wide applications of FZD in food-producing animals, the FZD residues were frequently found in foodstuffs. However, continual long-term intake or excessive residues with small doses of FZD could result in numerous side effects, such as hepatotoxicity, carcinogenicity, mutagenesis, and teratogenic effects.…”

Section: Introductionmentioning

confidence: 99%

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Vanadium Carbide-Entrapped Graphitic Carbon Nitride Nanocomposites: Synthesis and Electrochemical Platforms for Accurate Detection of Furazolidone

Kokulnathan

Wang

2020

ACS Appl. Nano Mater.

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Recently, two-dimensional nanomaterials have received great attention in the field of electrochemical applications because of their outstanding physicochemical properties. In this research, we developed vanadium carbide entrapped on graphitic carbon nitride nanosheets (VC/g-CN NSs) as a highly efficient electrocatalyst for the determination of furazolidone (FZD) in biological samples. The VC/g-CN NSs nanocomposite was systematically characterized by various analytical and spectroscopic techniques. The electrochemical performance of the VC/g-CN NSs-modified glassy carbon electrode (GCE) for the FZD detection was studied by the cyclic voltammetry and amperometric methods. On the one hand, the fabricated electrode offers numerous active sites with the large electron-transfer rate and the rapid mass transport ability to enhance the electrochemical activity toward the FZD detection. Under the optimization conditions, the VC/g-CN NSs modified electrode showed a wide detection range (0.004−141 μM), very low detection limit (0.5 nM), excellent selectivity, and reproducibility. Compared to the previous studies, the fabricated VC/g-CN NSs/GCE achieves the lowest limit of detection and the widest linear rangetoward the FZD detection. Furthermore, the fabricated sensor was successfully applied to determine FZD in the biological samples with satisfactory results.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Vanadium Carbide-Entrapped Graphitic Carbon Nitride Nanocomposites: Synthesis and Electrochemical Platforms for Accurate Detection of Furazolidone

Kokulnathan

Wang

2020

ACS Appl. Nano Mater.

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“…This powerful strategy focuses on targeting drugs to a desirable group of cells or tissue, reducing the systemic dose, and increasing the amount of active agent that reaches the aimed site of action while minimizing undesired side effects of the drugs [ 1 ]. A selection of polymeric formulations designed as micelles, hydrogels, nanospheres, and nanocapsules have been studied as suitable systems for the delivery of classical organic [ 2 , 3 ] and metal-based therapeutic agents [ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 ]. The polymeric nanocarrier-assisted drug delivery systems have attracted significant research interest mainly due to their notable properties.…”

Section: Introductionmentioning

confidence: 99%

Polymeric Nanosystems Applied for Metal-Based Drugs and Photosensitizers Delivery: The State of the Art and Recent Advancements

2022

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Nanotechnology-based approaches for targeting the delivery and controlled release of metal-based therapeutic agents have revealed significant potential as tools for enhancing the therapeutic effect of metal-based agents and minimizing their systemic toxicities. In this context, a series of polymer-based nanosized systems designed to physically load or covalently conjugate metal-based therapeutic agents have been remarkably improving their bioavailability and anticancer efficacy. Initially, the polymeric nanocarriers were applied for platinum-based chemotherapeutic agents resulting in some nanoformulations currently in clinical tests and even in medical applications. At present, these nanoassemblies have been slowly expanding for nonplatinum-containing metal-based chemotherapeutic agents. Interestingly, for metal-based photosensitizers (PS) applied in photodynamic therapy (PDT), especially for cancer treatment, strategies employing polymeric nanocarriers have been investigated for almost 30 years. In this review, we address the polymeric nanocarrier-assisted metal-based therapeutics agent delivery systems with a specific focus on non-platinum systems; we explore some biological and physicochemical aspects of the polymer–metallodrug assembly. Finally, we summarize some recent advances in polymeric nanosystems coupled with metal-based compounds that present potential for successful clinical applications as chemotherapeutic or photosensitizing agents. We hope this review can provide a fertile ground for the innovative design of polymeric nanosystems for targeting the delivery and controlled release of metal-containing therapeutic agents.

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“…Different biopolymer-based hydrogels such as carboxy methyl cellulose; chitosan, agar, bacterial cellulose, and alginate etc. have been studied so far for academically and applied in various applied fields (Chen et al 2017a;Ali et al 2017a, b, c;Xu et al 2017b;Silva et al 2019;Chanthiwong et al 2020;Khalil et al 2020). Amongst them alginate is one of the most extensively used polymers owing to its highly biocompatible and biodegradable nature.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and catalytic evaluation of silver@nickel oxide and alginate biopolymer nanocomposite hydrogel beads

et al. 2021

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In this study, silver-nickel oxide/ calcium alginate (Ag@NiO/Alg) hydrogel beads were synthesized. The preparation of Ag@NiO was carried out in two steps: 1) synthesizing the nickel oxide nanoparticle through precipitation method, and 2) adhering of the Ag + ion from silver nitrate solution and reduction with sodium borohydride. The nanomaterial was mixed with alginate biopolymer aqueous solution and extruded through syringe in a dropwise manner into a CaCl2 aqueous solution for inotropic crosslinking. Through this method, Ag@NiO/Alg beads were formed which were characterized by different instrumental techniques. The catalytic efficiency of Ag@NiO/Alg was evaluated for the reduction of rhodamine B (RhB) and methyl orange (MO), in the presence of sodium borohydride reducing agent. The uncatalyzed RhB and MO reduction reactions did not show a significant decrease in the absorbance value at λmax within the given experimental time. It was due to the large kinetic barrier. A small decrease in the absorbance value for uncatalyzed reaction in the presence of very high concentration of 3 reducing agent was observed, indicating that the reactions are thermodynamically feasible. After applying various kinetic order equations to the experimental data, the reactions were found to follow pseudo-first order kinetics using the Ag@NiO/Alg catalyst. The apparent rate constants (kapp) were determined as 0.33358 min -1 and 0.20882 min -1 for catalytic reduction of RhB and MO, respectively. Furthermore, reduction reactions were studied at varying dye concentration and catalyst dosages. The recovered catalyst was reused up to five cycles without significant drop in the activity.

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Concomitant and controlled release of furazolidone and bismuth(III) incorporated in a cross-linked sodium alginate-carboxymethyl cellulose hydrogel

Cited by 39 publications

References 30 publications

Vanadium Carbide-Entrapped Graphitic Carbon Nitride Nanocomposites: Synthesis and Electrochemical Platforms for Accurate Detection of Furazolidone

Vanadium Carbide-Entrapped Graphitic Carbon Nitride Nanocomposites: Synthesis and Electrochemical Platforms for Accurate Detection of Furazolidone

Polymeric Nanosystems Applied for Metal-Based Drugs and Photosensitizers Delivery: The State of the Art and Recent Advancements

Synthesis and catalytic evaluation of silver@nickel oxide and alginate biopolymer nanocomposite hydrogel beads

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