The importance of access to spatial data for development and resource management is widely acknowledged worldwide. Unrestricted, reliable and efficient access to accurate, timely, and up-to-date spatial data may be achieved through a Spatial Data Infrastructure (SDI). Thus, most developed countries implemented and continue to develop their SDI. In Africa, there is a growing number of governments committed to SDI development. This paper aims to contribute to initialize an SDI in Mozambique. We identified and characterized through a survey the government institutions producing, sharing, and using spatial data in the country to estimate their potential contribution to the development of the Mozambican SDI. We found 12 institutions producing 15 thematic datasets which can constitute the core of the SDI for Mozambique. Two government agencies have the technical skills and policies to make spatial data available to the public. Based on the possible contribution of these institutions, this paper proposes an SDI for Mozambique based on four pillars: i) organizational framework; ii) legal framework; iii) technical framework; and iv) accessibility.