Concepts and characteristics of the ‘COST Reference Microplasma Jet’

Golda, Judith; Held, Julian; Redeker, B.; Konkowski, M.; Beijer, P.; Sobota, Ana; Kroesen, Gmw Gerrit; Braithwaite, Nicholas; Reuter, Stephan; Turner, M. M.; Gans, Timo; O’Connell, Deborah; Gathen, Volker Schulz-von der

doi:10.1088/0022-3727/49/8/084003

Cited by 165 publications

(260 citation statements)

References 38 publications

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“…The plasma source used in this study is the COST‐action reference plasma source (described in detail by Golda et al) . It can be divided into three main components: (i) the electrode assembly; (ii) the gas connector; and (iii) the housing (constituting out of the electric connections and the voltage and current probes).…”

Section: Methodssupporting

confidence: 89%

Cold atmospheric plasma treatment of melanoma and glioblastoma cancer cells

Vermeylen¹,

Waele²,

Vanuytsel

et al. 2016

Plasma Processes & Polymers

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In this paper, two types of melanoma and glioblastoma cancer cell lines are treated with cold atmospheric plasma to assess the effect of several parameters on the cell viability. The cell viability decreases with treatment duration and time until analysis in all cell lines with varying sensitivity. The majority of dead cells stains both AnnexinV (AnnV) and propidium iodide, indicating that the plasma‐treated non‐viable cells are mostly late apoptotic or necrotic. Genetic mutations might be involved in the response to plasma. Comparing the effects of two gas mixtures, as well as indirect plasma‐activated medium versus direct treatment, gives different results per cell line. In conclusion, this study confirms the potential of plasma for cancer therapy and emphasizes the influence of experimental parameters on therapeutic outcome.

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Section: Methodssupporting

confidence: 89%

Cold atmospheric plasma treatment of melanoma and glioblastoma cancer cells

Vermeylen¹,

Waele²,

Vanuytsel

et al. 2016

Plasma Processes & Polymers

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“…The micro atmospheric pressure plasma jet (μ-APPJ) has been in the focus of many studies in the past and is described in great detail in [4,[26][27][28][29][30]. Here, a short description of the recent design will be given together with the operating procedure.…”

Section: Atmospheric Pressure Ion Mass Spectrometrymentioning

confidence: 99%

Methods of gas purification and effect on the ion composition in an RF atmospheric pressure plasma jet investigated by mass spectrometry

et al. 2016

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The analysis of the ion chemistry of atmospheric pressure plasmas is essential to evaluate ionic reaction pathways during plasma-surface or plasma-analyte interactions. In this contribution, the ion chemistry of a radio-frequency atmospheric pressure plasma jet (μ-APPJ) operated in helium is investigated by mass spectrometry (MS). It is found, that the ion composition is extremely sensitive to impurities such as N 2 , O 2 and H 2 O. Without gas purification, protonated water cluster ions of the form H + (H 2 O) n are dominating downstream the positive ion mass spectrum. However, even after careful feed gas purification to the sub-ppm level using a molecular sieve trap and a liquid nitrogen trap as well as operation of the plasma in a controlled atmosphere, the positive ion mass spectrum is strongly influenced by residual trace gases. The observations support the idea that species with a low ionization energy serve as a major source of electrons in atmospheric pressure helium plasmas. Similarly, the neutral density of atomic nitrogen measured by MS in a He/N 2 mixture is varying up to a factor 3, demonstrating the significant influence of impurities on the neutral species chemistry as well.

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“…During the ignition phase, a discharge is formed between the electrodes and afterward emitted with a high electric field in form of a bullet into the surrounding air and onto the target [5][6][7][8]. One important value for the comparison of different plasma sources is the input power [9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Power measurement for an atmospheric pressure plasma jet at different frequencies: distribution in the core plasma and the effluent

Gerling

Brandenburg

Wilke

et al. 2017

Eur. Phys. J. Appl. Phys.

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Abstract. The characterization of electrical power distribution in an atmospheric pressure plasma jet operated at six different frequencies is investigated by measurement of input power and voltage-charge plots for the core plasma and the plasma in the effluent. The frequency change is further characterized by measuring the temperature in the effluent at different positions and input power levels. The power input into the core plasma is limited to about 1 W for a wide range of frequencies while the total input power and thus the power input into the effluent increases continuously with frequency.

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Concepts and characteristics of the ‘COST Reference Microplasma Jet’

Cited by 165 publications

References 38 publications

Cold atmospheric plasma treatment of melanoma and glioblastoma cancer cells

Cold atmospheric plasma treatment of melanoma and glioblastoma cancer cells

Methods of gas purification and effect on the ion composition in an RF atmospheric pressure plasma jet investigated by mass spectrometry

Power measurement for an atmospheric pressure plasma jet at different frequencies: distribution in the core plasma and the effluent

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