Concentrations of NEFA, β-HBA, triglycerides, and certain blood metabolitesin healthy colored Angora goats during the peripartum period

Abstract

The aim of this study was to determine the changes in serum nonesterified fatty acid (NEFA), serum β-hydroxybutyric acid (β-HBA), triglycerides, Ca, Na, and other metabolites (bilirubin, glutamate dehydrogenase (GLDH)) in the blood of grazing, healthy goats at the time of parturition. Blood samples were taken weekly from the jugular vein of 11 goats, starting at week 2 antepartum (ap) until week 9 postpartum (pp). NEFA and β-HBA concentrations increased from week 2 ap to 2 weeks pp. The increase in NEFA level was not significant; however, the β-HBA levels were higher (P < 0.05) 2 weeks pp compared to the levels at 2 weeks ap. Triglycerides were recorded at maximum levels (P < 0.05) 2 weeks ap, with the lowest concentrations at 3 weeks pp. Bilirubin levels consistently increased up to 7 weeks pp, followed by a decrease. However, these changes were not significant. Similarly, GLDH activities increased until week 8 pp. A significant difference (P < 0.05) was recorded between the 1st week and 8th week pp. Ca and Na levels were lower during the 1st week pp and increased at 3 weeks pp. The results show that there are characteristic alterations of some metabolic blood parameters in goats around the time of parturition, which may be related to physiological changes.

Blood metabolites of extensively reared Croatian multi-coloured goats during early lactation and early gravidity

“…To our knowledge, there are no reference values for NEFA in goats; KANEKO et al (2008) mention a very wide range for cows (0.378 -3.78 mmol/L), but none for sheep and goats. NEFA values in this research were significantly higher (P<0.0001) in early lactation L. Radin et al: Blood metabolites of Croatian multi-coloured goat (March) than at the beginning of gravidity (October), which is consistent with results for sheep, goats and cows published by various authors (EŞKI et al, 2015;RADIN et al, 2015). This rise corresponds to physiological adaptation to gravidity and the beginning of lactation.…”

“…Meeting the nutrient requirements for grazing and browsing animals is challenging, and can lead to metabolic disorders (EŞKI et al, 2015), especially in early spring when the dry matter content of pasture grasses, plant species and herbage is very low. The most valuable parameters for assessment of the ruminants' energy status are plasma concentrations of non-esterified fatty acids (NEFA), triglycerides and β-hydroxybutirate (BHB) (FERNANDEZ et al, 2007) for which there are no reference values for goats in the textbooks (KANEKO et al, 2008).…”

Serum cholesterol levels in Hair goats of Aksaray Region

“…In the present study, triglyceride levels showed statistically significant differences in terms of gender and age. In this study, the amounts of triglyceride have been detected higher than the other studies (Tanrıtanır et al, 2010;Devrim et al 2015, Eşki et al 2015.…”

Earwax metabolomics: An innovative pilot metabolic profiling study for assessing metabolic changes in ewes during periparturition period

“…Regarding Ca levels in earwax, they significantly decrease in pre- and postparturient samples (P<0.0001) matching results on Ca levels in plasma and serum presented in earlier studies [ 48 ], where it was reported that Ca levels markedly decrease during late pregnancy, reaching minimum levels at parturition, then continued to decrease for the first few weeks postpartum, ultimately returning to the level before pregnancy [ 45 ]. This could be attributed to increased demand for Ca for mineralization of fetal skeleton.…”