Concentrations of circulating hormones during the interval between pulses of a PGF2α metabolite in mares and heifers

Ginther, O.J.; Rodríguez, María Belén; Beg, M.A.

doi:10.1016/j.anireprosci.2011.08.009

Cited by 14 publications

(7 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In contrast, progesterone concentrations decreased linearly throughout the pulse (Figs. 4 and 7; see Progesterone Rebound Within a Natural PGFM Pulse in Cattle but Not in Horses) [8,10,16]. There were no progesterone rebounds.…”

Section: Ginther and Begmentioning

confidence: 81%

“…Horses, unlike cattle, do not show progesterone concentration changes in different directions within a spontaneous [8,10] or simulated [26] pulse of PGFM (Figs. 4, 6, and 7).…”

Section: Progesterone Rebound Within a Natural Pgfm Pulse In Cattle Bmentioning

confidence: 93%

“…Furthermore, progesterone decreases linearly throughout the luteolytic period or during the hours of a PGFM pulse and between the ending nadir of a PGFM pulse and the beginning nadir of the next PGFM pulse (Fig. 7) [10].…”

Section: Progesterone Rebound Within a Natural Pgfm Pulse In Cattle Bmentioning

confidence: 98%

“…Concentrations of PGF in the systemic circulation are usually assessed by measuring PGFM in both heifers/cows and mares, owing to the short half-life of PGF [9]. The mean peak-to-peak interval between neighboring PGFM pulses during luteolysis and postluteolysis is 8 h in heifers and 9 h in mares [10].…”

Section: Luteolysis In Cattle and Horsesmentioning

confidence: 99%

“…Progesterone decreases linearly during each pulse and between the pulses. Adapted from[10] with permission.…”

mentioning

confidence: 98%

See 4 more Smart Citations

Dynamics of Circulating Progesterone Concentrations Before and During Luteolysis: A Comparison Between Cattle and Horses1

Ginther

Beg

2012

Biology of Reproduction

Self Cite

View full text Add to dashboard Cite

The profile of circulating progesterone concentration is more dynamic in cattle than in horses. Greater prominence of progesterone fluctuations in cattle than in horses reflect periodic interplay in cattle between pulses of a luteotropin (luteinizing hormone; LH) and pulses of a luteolysin (prostaglandin F2alpha; PGF2alpha). A dose of PGF2alpha that induces complete regression of a mature corpus luteum with a single treatment in cattle or horses is an overdose. The overdose effects on the progesterone profile in cattle are an immediate nonphysiological increase taking place over about 30 min, a decrease to below the original concentration, a dose-dependent rebound 2 h after treatment, and a progressive decrease until the end of luteolysis. An overdose of PGF2alpha in horses results in a similar nonphysiological increase in progesterone followed by complete luteolysis; a rebound does not occur. An overdose of PGF2alpha and apparent lack of awareness of the rebound phenomenon has led to faulty interpretations on the nature of spontaneous luteolysis. A transient progesterone suppression and a transient rebound occur within the hours of a natural PGF2alpha pulse in cattle but not in horses. Progesterone rebounds are from the combined effects of an LH pulse and the descending portion of a PGF2alpha pulse. A complete transitional progesterone rebound occurs at the end of preluteolysis and the beginning of luteolysis and returns progesterone to its original concentration. It is proposed that luteolysis does not begin in cattle until after the transitional rebound. During luteolysis, rebounds are incomplete and gradually wane. A partial rebound during luteolysis in cattle is associated with a concomitant increase in luteal blood flow. A similar increase in luteal blood flow does not occur in mares.

show abstract

Section: Ginther and Begmentioning

confidence: 81%

“…Horses, unlike cattle, do not show progesterone concentration changes in different directions within a spontaneous [8,10] or simulated [26] pulse of PGFM (Figs. 4, 6, and 7).…”

Section: Progesterone Rebound Within a Natural Pgfm Pulse In Cattle Bmentioning

confidence: 93%

Section: Progesterone Rebound Within a Natural Pgfm Pulse In Cattle Bmentioning

confidence: 98%

Section: Luteolysis In Cattle and Horsesmentioning

confidence: 99%

“…Progesterone decreases linearly during each pulse and between the pulses. Adapted from[10] with permission.…”

mentioning

confidence: 98%

See 3 more Smart Citations

Dynamics of Circulating Progesterone Concentrations Before and During Luteolysis: A Comparison Between Cattle and Horses1

Ginther

Beg

2012

Biology of Reproduction

Self Cite

View full text Add to dashboard Cite

show abstract

Hormone concentration changes temporally associated with the hour of transition from preluteolysis to luteolysis in mares

Ginther

Beg

2011

Animal Reproduction Science

View full text Add to dashboard Cite

The end of the tour de force of the corpus luteum in mares

Ginther¹

2012

Theriogenology

View full text Add to dashboard Cite

Concentrations of circulating hormones during the interval between pulses of a PGF2α metabolite in mares and heifers

Cited by 14 publications

References 23 publications

Dynamics of Circulating Progesterone Concentrations Before and During Luteolysis: A Comparison Between Cattle and Horses1

Dynamics of Circulating Progesterone Concentrations Before and During Luteolysis: A Comparison Between Cattle and Horses1

Hormone concentration changes temporally associated with the hour of transition from preluteolysis to luteolysis in mares

The end of the tour de force of the corpus luteum in mares

Contact Info

Product

Resources

About