Concentrations of bacteria in cerebrospinal fluid of patients with bacterial meningitis

Feldman, William E.

doi:10.1016/s0022-3476(76)80003-0

Cited by 202 publications

(88 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The CSF white blood count at diagnosis is not related to the CSF bacterial content (Feldman, 1976). It is, however, an indicator of the patient's response to infection.…”

Section: Discussionmentioning

confidence: 91%

Lumbar punctures, meningitis, and persisting pleocytosis.

Connolly¹

1979

Archives of Disease in Childhood

View full text Add to dashboard Cite

“…The CSF white blood count at diagnosis is not related to the CSF bacterial content (Feldman, 1976). It is, however, an indicator of the patient's response to infection.…”

Section: Discussionmentioning

confidence: 91%

Lumbar punctures, meningitis, and persisting pleocytosis.

Connolly¹

1979

Archives of Disease in Childhood

View full text Add to dashboard Cite

“…However in the largest cohort since the 1980s, hearing loss developed in 7 percent of cases, one-quarter of which were detected after the routine follow-up period had ended (19). Factors related to the outcome of bacterial meningitis in children include age at the time of diagnosis, course or progression of disease before antibiotic therapy is effective, etiologic agent, the number of organisms or the quantity of polysaccharide material present in the meninges and delayed sterilization of the CSF (2,(20)(21)(22)(23). We found that children under 24 months of age developed neurologic sequela more commonly than older children.…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Prognostic Factors in Childhood Bacterial Meningitis: A Multicenter Study

Türel¹,

Yıldırım²,

Yüksel³

et al. 2013

Balkan Med J

View full text Add to dashboard Cite

“…However, the number of bacteria in the cerebrospinal fluid of children with meningitis typically reaches between 105 and 107 CFU/ml (35). Some clinical data support the use of a higher inoculum for susceptibility testing.…”

Section: Effect Of Inoculum Sizementioning

confidence: 99%

Haemophilus influenzae: antibiotic susceptibility

Needham

1988

Clin Microbiol Rev

View full text Add to dashboard Cite

Ampicillin resistance was first reported among clinical isolates of Haemophilus influenzae in 1972. Reports of chloramphenicol resistance followed shortly thereafter. The principal mechanism of resistance to these two antibiotics is enzymatic. Although other mechanisms have been described, they are found in comparatively few strains. The genetic information for the inactivating enzymes is plasmid mediated and therefore readily transmissible to susceptible strains. Consequently, effective therapy for invasive disease caused by this pathogen has been seriously compromised. As antibiotic susceptibility became less predictable, in vitro testing became increasingly important. Unfortunately, the standardization of methods for laboratory testing has been slow and complicated by the fastidious nature of the organisms. This review traces the development of antibiotic resistance in H. influenzae, discusses the mechanisms which appear to be important in mediating resistance, explores newer antimicrobial agents which might be useful in the treatment of infection, and analyzes the various approaches to in vitro testing.

show abstract

Concentrations of bacteria in cerebrospinal fluid of patients with bacterial meningitis

Cited by 202 publications

References 14 publications

Lumbar punctures, meningitis, and persisting pleocytosis.

Lumbar punctures, meningitis, and persisting pleocytosis.

Clinical Characteristics and Prognostic Factors in Childhood Bacterial Meningitis: A Multicenter Study

Haemophilus influenzae: antibiotic susceptibility

Contact Info

Product

Resources

About