Concentraciones plasmáticas de 25-OH vitamina D y parathormona en sangre de cordón umbilical

Gómez, Sandra Ortigosa; Garcı́a-Algar, Óscar; Sierra, A. Mur; Costa, Roser Ferrer; Lezcano, Antonio Carrascosa; Yeste, Diego

doi:10.4321/s1135-57272015000100008

Cited by 13 publications

(4 citation statements)

References 35 publications

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“…Se tomó en cuenta el consumo diario de vitamina D en la dieta de las participantes del estudio. Este resultó bajo, similar a lo reportado por Ortigosa, et al 39 en una muestra que incluye mujeres sudamericanas radicadas en Barcelona, España. Dicho resultado puede ser secundario al hecho de que sean originarias de Sudamérica y continúen con hábitos y costumbres alimenticios similares a los de su lugar de origen.…”

Section: Discussionunclassified

Deficiencia de vitamina D en madres y neonatos mexicanos

Ochoa-Correa

Hernández

Pérez

et al. 2017

GMM

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Section: Discussionunclassified

Deficiencia de vitamina D en madres y neonatos mexicanos

Ochoa-Correa

Hernández

Pérez

et al. 2017

GMM

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“…Maternal data that may correlate with neonatal vitamin D levels at birth, including the pre-pregnancy weight [35], skin color [13], and sun exposure during pregnancy [36] were not collected. However, it is unlikely that these limitations will affect the observed rate of vitamin D deficiency and insufficiency seen at birth in the studied infants.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and risk factors for vitamin D insufficiency and deficiency at birth and associated outcome

et al. 2016

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BackgroundOccurrence and consequence of cord blood (CB) vitamin D insufficiency/deficiency has not been adequately explored despite rising concern regarding this topic in pediatrics. This study was designed to determine the rate, maternal risk factors, and clinical outcomes in infants in association with vitamin D insufficient/deficient status at birth.MethodsAmerican Academy of Pediatrics (AAP) defined levels (ng/mL) were utilized to categorize the vitamin D status in CB samples as deficient (5–15), insufficient (16–20), and sufficient (21–100). We used descriptive statistics and multiple regression models to identify the rate and factors associated with vitamin D deficiency/insufficiency and related outcomes in the enrolled mother-infant pairs.ResultsThis prospective study was conducted at a single center on postpartum women and their infants. Vitamin D deficiency and insufficiency was recorded in 38.9 and 29.8% respectively of the 265 CB samples. Deficient CB vitamin D levels in infants were associated with maternal Black, Hispanic, or Asian race/ethnicity, younger age, and increased number of pregnancies. The likelihood for infants to be born with an insufficient vitamin D level increases with younger maternal age and the number of pregnancies as well as Asian ethnicity. We did not find an association between the vitamin D status at birth and pre-discharge clinical characteristics of the neonates.ConclusionsThe likelihood for an infant to be born with vitamin D deficiency/insufficiency is relatively high and is related mainly to younger maternal age, gravidity, and non-White race/ethnicity. Our findings raise a question regarding the adequacy of the AAP recommended vitamin D supplementation requirements without knowing the infant’s vitamin D status at birth.

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“…The effects of dietary and plasma calcium and plasma 25-hydroxyvitamin D (25(OH)D) on PTH have been well studied [18,19]. Although other determinants that might influence PTH levels have been suggested by prior research in the general population, such as the body mass index (BMI), ethnicity, smoking, season, and age, research on PTH determinants in pregnant women is scanty [2,3,18,[20][21][22][23][24][25][26][27][28][29]. Correlation between PTH and 25(OH)D levels has been the main focus of studies in women of childbearing age and less frequently during pregnancy [21,[23][24][25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Parathyroid Hormone in Pregnancy: Vitamin D and Other Determinants

et al. 2021

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We aimed to assess the parathyroid hormone (PTH) concentration in pregnant women at the beginning of pregnancy (1st trimester) and within days before delivery (3rd trimester) and evaluate its determinants. From September 2014 through December 2015 in a cross-sectional study, 204 women in the 1st trimester of pregnancy and 203 women in the 3rd trimester of pregnancy were recruited. Blood samples were collected to measure PTH and circulating 25-hydroxy-vitamin D (25(OH)D) concentrations. Lifestyle and demographic data were collected using a questionnaire. Serum 25(OH)D and PTH were inversely correlated in both early and late pregnancy. Our analyses suggest that in the 3rd trimester of pregnancy, a 25(OH)D level of 18.9 ng/mL (47.3 nmol/L) could serve as an inflection point for the maximal suppression of PTH. Statistically significant determinants of PTH concentrations in multiple regression were 25(OH)D concentrations, season, multiparity and education of the partner (all p < 0.05) in early pregnancy. In late pregnancy, 25(OH)D concentrations and country of origin were statistically significant determinants of PTH concentrations (all p < 0.05). These factors and their effect on PTH appear to be vastly determined by 25(OH)D; however, they might also affect PTH through other mechanisms besides 25(OH)D.

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Concentraciones plasmáticas de 25-OH vitamina D y parathormona en sangre de cordón umbilical

Abstract: There is a high prevalence of low levels of vitamin D after winter months in cord blood. The lowest 25(OH D levels were observed in Indo-Pakistani ethnicity, dark phototype and deficient sun exposure.

Cited by 13 publications

References 35 publications

Deficiencia de vitamina D en madres y neonatos mexicanos

Deficiencia de vitamina D en madres y neonatos mexicanos

Prevalence and risk factors for vitamin D insufficiency and deficiency at birth and associated outcome

Parathyroid Hormone in Pregnancy: Vitamin D and Other Determinants

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