Computerized tomography in the diagnosis of intramedullary metastases

Smaltino, F; Bernini, F.P.; Santoro, Silvia

doi:10.1007/bf01402085

Cited by 20 publications

(10 citation statements)

References 7 publications

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“…3F) showed the lesions to better advantage. CT has shown hyperdensities in the spinal cord on both plain and IV contrast-enhanced studies [4,5]. Plain and IV-enhanced CT scans, however, have not been used extensively in patients with this disease.…”

Section: Imaging Studiesmentioning

confidence: 99%

“…Plain and IV-enhanced CT scans, however, have not been used extensively in patients with this disease. While the potential value of intrathecal metrizamide has been mentioned [5], the use of metrizamide CT scans has not been reported.…”

Section: Imaging Studiesmentioning

confidence: 99%

“…The sensitivity of these procedures in the detection of spinal neoplasms in general has been described [5,[21][22][23][24][25]]; however, a detailed analysis of the appearance of spinal cord metastases (whether of extra-or intra-CNS origin) on all these newer imaging studies has not, to our knowledge, been published. Our object is to report our experience in imaging these frequently elusive intramedullary neoplasms and to determine which was the most sensitive test in detecting this tumor.…”

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confidence: 99%

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Intramedullary spinal cord metastases, mainly of nonneurogenic origin

Post

Quencer

Green

et al. 1987

American Journal of Roentgenology

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Section: Imaging Studiesmentioning

confidence: 99%

Section: Imaging Studiesmentioning

confidence: 99%

mentioning

confidence: 99%

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Intramedullary spinal cord metastases, mainly of nonneurogenic origin

Post

Quencer

Green

et al. 1987

American Journal of Roentgenology

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“…One third of adult spinal cord tumors are intramedullary and rest are extramedullary. Of the tumors metastasizing to the spinal cord lung carcinoma is the most common accounting for 50% followed by breast carcinoma, Lymphoma, melanoma, colorectal carcinoma, Hodgkin disease, head and neck carcinoma and leukemia [5] [6]. Primary tumors less commonly reported to metastasize to spine include schwannoma, mesothelioma, merkel tumor, plasmacytoma, teratoma, as well as basal cell, parotid, nasopharyngeal, laryngeal, esophageal, gall bladder, pancreas, ovarian, endometrial, and urinary bladder tumors.…”

Section: Discussionmentioning

confidence: 99%

Multiple Spinal Intradural-Intramedullary Involvement by Metastatic Carcinoma with Neuroendocrine Differentiation with Occult Primary—An Unusual Case Report and Review of Literature

Gupta¹,

Sinha²

2016

OJPathology

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Although vertebral column is recognized as the most common site for bony metastasis in patient with systemic malignancy, intramedullary metastases to the spinal cord is infrequent. Between 5% -10% of cancer patients develop spinal metastasis during the course of their diseases. Intramedullary tumors are rare, comprising 3.5% of spinal metastasis. Most metastatic spinal lesions (70%) are found at the thoracic level, 20% in lumbar region and 10% in the cervical region. We report a rare biopsy proven case of intramedullary spinal metastatic carcinoma with neuroendocrine differentiation because of its unusual presentation, involving spine at multiple noncontiguous levels, which appeared as irregular small nodules on MRI. The primary tumor was most likely from occult primary in lung. Biopsy from the spinal lesion established the diagnosis of metastatic carcinoma with neuroendocrine differentiation. Therefore, in patients with spinal metastasis, a thorough work up is advised to evaluate primary site. This would help to delineate the nature and the extent of the systemic disease. We highlighted herein the clinical presentation, radiological findings particularly MRI and role of biopsy in the diagnosis and treatment of intramedullary spinal metastasis.

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“…Regardless of their histology, ISCM are even more rare accounting for only 0.9-5% of all spinal metastases 1,2,13,14 . This is particularly striking, since intracerebral metastases account for 55% of all intracranial tumors 6 .…”

Section: Epidemiologymentioning

confidence: 99%

Intramedullary Spinal Cord Metastases: Review of the Literature

Hrabálek¹

2010

BIOMED PAP

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Aims. To review the epidemiology, dissemination, clinical presentation, diagnosis, treatment, survival and functional outcome of intramedullary spinal cord metastases (ISCM).Methods. Literature review of all surgically treated cases of ISCM and all described cases of ISCM of breast carcinoma.Results. 42 references to 87 surgically treated cases of ISCM were found, 13 references to 27 cases with diagnosed and treated ISCM of breast carcinoma. In only 9 cases of spinal cord metastases of breast cancer was surgical resection of ISCM done (10% of all surgically treated ISCM).Conclusions. Three treatment modalities are available for ISCM: radiotherapy, chemotherapy, and surgery. The gold standard remains radiotherapy.Microsurgical resection of a focal intramedullary mass appears to be feasible and should be considered in selected cases. Patients who have no evidence of widespread organ metastases or multiple intramedullary lesions and who have a life expectancy of at least a few months with tumours of non-lymphoma histology should be considered for tumor resection.In conclusion, ISCM are difficult to treat lesions, but early diagnosis, careful surgical management and maintenance therapy may substantially contribute to a satisfactory functional outcome and prolonged survival.

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Computerized tomography in the diagnosis of intramedullary metastases

Abstract: SummaryThe authors describe two cases in which computerized tomography (CT) revealed the presence of cervical intramedullary metastases in the form of increased density areas.

Cited by 20 publications

References 7 publications

Intramedullary spinal cord metastases, mainly of nonneurogenic origin

Intramedullary spinal cord metastases, mainly of nonneurogenic origin

Multiple Spinal Intradural-Intramedullary Involvement by Metastatic Carcinoma with Neuroendocrine Differentiation with Occult Primary—An Unusual Case Report and Review of Literature

Intramedullary Spinal Cord Metastases: Review of the Literature

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