Computer programs to estimate genetic contributions and related parameters

Miller, Danielle; Rathie, K. A.

doi:10.1007/bf00277556

Cited by 2 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…James (1962b) derived equations for the sampling variances of the proportions of genes of sires and dams from the matings of their progeny. An efficient way of calculating genetic contributions from pedigrees was presented by James (1972), and a FORTRAN program (called CØNTRIB) implementing this strategy was published by Miller & Rathie (1972) in a companion paper. More recently, Nicola Man, John James and Frank Nicholas explored partial inbreeding in Australian Holstein Friesian cattle (Man et al 2001(Man et al , 2002 and found that inbreeding depression on somatic cell count as well as milk, fat and protein production varies with respect to founders.…”

Section: Introductionmentioning

confidence: 99%

grain: a computer program to calculate ancestral and partial inbreeding coefficients using a gene dropping approach

Baumung

Farkas

Boichard

et al. 2015

J Animal Breeding Genetics

View full text Add to dashboard Cite

GRain is freely available software intended to enable and promote testing of hypotheses with respect to purging and heterogeneity of inbreeding depression. The program is based on a stochastic approach, the gene dropping method, and calculates various coefficients from large and complex pedigrees. GRain calculates, together with the 'classical' inbreeding coefficient, ancestral inbreeding coefficients proposed by Ballou, (1997) J. Hered., 88, 169 and Kalinowski et al., (2000) Conserv. Biol., 14, 1375 as well as an ancestral history coefficient (AHC ), defined here for the first time. AHC is defined as the number that tells how many times during pedigree segregation (gene dropping) a randomly taken allele has been in IBD status. Furthermore, GRain enables testing of heterogeneity and/or purging of inbreeding depression with respect to different founders/ancestors by calculating partial coefficients for all previously obtained coefficients.

show abstract

Section: Introductionmentioning

confidence: 99%