Computed Tomography, Ultrasound and Lymphography in the Diagnosis of Malignant Lymphoma

Magnusson, Anders; Hagberg, Hans; Hemmingsson, Anders; Lindgren, P. G.

doi:10.1177/028418518202300104

Cited by 19 publications

(4 citation statements)

References 20 publications

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“…Computed tomography (CT) is an effective modality for diagnosing diseases in retroperitoneal, mediastinal and cervical lymph nodes (1, 2,4,6). Sometimes it can be difficult to differentiate between pathologically enlarged lymph nodes and blood vessels (5).…”

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confidence: 99%

Contrast Enhancement of Pathologic Lymph Nodes Demonstrated by Computed Tomography

Magnusson¹,

Andersson²,

Larsson³

et al. 1989

Acta Radiol

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Enlarged mediastinal, retroperitoneal and pelvic lymph nodes are often difficult to differentiate from vascular structures. Contrast medium is therefore used to help to discriminate arteries and veins from lymph nodes. This study was undertaken to investigate the degree to which pathologic lymph nodes become enhanced after an intravenous bolus injection of contrast medium. Computed tomography was performed in 25 patients with enlargement of retroperitoneal lymph nodes due to primary lymphoproliferative disease or metastases. A dynamic sequence of a well delineated lymph node was obtained over a period of two minutes. Contrast enhancement was seen in all lymph nodes, but of varying degree. The enhancement was correlated to that observed in the inferior vena cava. Most examined lymph nodes showed slight or moderate enhancement, but in five instances strong enhancement, more than 75 per cent of that of the vena cava, was found. These nodes could possibly have been misinterpreted as blood vessels.

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confidence: 99%

Contrast Enhancement of Pathologic Lymph Nodes Demonstrated by Computed Tomography

Magnusson¹,

Andersson²,

Larsson³

et al. 1989

Acta Radiol

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“…Castellino's findings [20] in a similar very small series agree. Several authors have claimed that CT scanning is superior to LAG in assessing abdominal nodes [22,23,24]. Earl and associates [23] found no difference in the accuracy of CT scans and LAG with respect to node size.…”

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confidence: 99%

Staging laparotomy with splenectomy for Hodgkin's disease: The Stanford experience

1985

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The results of 825 staging laparotomies performed by surgeons at Stanford University Hospital are presented. The clinical stage was changed as a result of laparotomy in 43.2% of cases. Preoperative lymphangiography proved accurate in 78-80% of cases. In 321 patients (38.9%) the test results for the spleen were positive, and in 161 (50.2%) of these, the spleen was the only positive tissue sampled. Major complications occurred in 9.6% of cases; most were wound and upper respiratory infections. The results of laparotomy have identified a subgroup of stage IliA patients who benefit from early systemic chemotherapy. Staging laparotomy with splenectomy has proven to be a useful and safe clinical research tool and has been one of the major factors in increasing survival from Hodgkin's disease.

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“…Better acceptance by patients and the ability to perform unlimited repeat studies make CT the preferred procedure. However, the discordant findings between lymphography and CT should caution those who may abandon lymphography completely (46,56,57).…”

Section: Lymphomasmentioning

confidence: 99%

Lymphography: An Old Technique Retains Its Usefulness

Guermazi

Brice²,

Hennequin³

et al. 2003

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Conventional lymphography has long been the method of choice for imaging the lymphatic system. However, the number of lymphographic studies performed in oncology centers has declined markedly since the introduction of cross-sectional imaging techniques, especially computed tomography (CT). Therefore, levels of expertise in both performing lymphography and interpreting lymphograms are falling. The unique ability of lymphography to demonstrate derangements of the internal architecture of normal-sized lymph nodes can be valuable and makes it more accurate than CT in evaluation of some lymphomas (especially Hodgkin disease) and genitourinary malignancies. In fact, lymphography and CT are complementary rather than mutually exclusive techniques for the staging of some lymphomas and genitourinary malignancies. In addition, lymphography opacifies the lymphatic channels and therefore may be a valuable tool for detection of lymphatic fistulas or lymphatic leakage. Finally, lymphography helps guide subsequent therapy in patients with lymphomas, genitourinary malignancies, or disorders of lymphatic flow.

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Computed Tomography, Ultrasound and Lymphography in the Diagnosis of Malignant Lymphoma

Cited by 19 publications

References 20 publications

Contrast Enhancement of Pathologic Lymph Nodes Demonstrated by Computed Tomography

Contrast Enhancement of Pathologic Lymph Nodes Demonstrated by Computed Tomography

Staging laparotomy with splenectomy for Hodgkin's disease: The Stanford experience

Lymphography: An Old Technique Retains Its Usefulness

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