Computed Tomography of Extracranial Chloroma

Nr, Dunnick; Dk, Heaston

doi:10.1097/00004728-198202000-00013

Cited by 10 publications

(8 citation statements)

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“…Granulocytic sarcoma arising from bony structures typically presents as a focal destructive osseous lytic lesion with either ill-defined borders, surrounding reactive sclerosis, or an associated adjacent soft tissue mass. 6,7,[17][18][19] The most frequent sites of osseous involvement are orbits, sacrum, sinuses, spine, sternum, and ribs. 18 In contrast, extramedullary granulocytic sarcoma occurring outside of the bone commonly presents as a soft tissue nodule or mass of similar attenuation or slightly increased attenuation compared with adjacent soft tissue structures (eg, skeletal muscles).…”

Section: Discussionmentioning

confidence: 99%

“…6,7,[17][18][19] The most frequent sites of osseous involvement are orbits, sacrum, sinuses, spine, sternum, and ribs. 18 In contrast, extramedullary granulocytic sarcoma occurring outside of the bone commonly presents as a soft tissue nodule or mass of similar attenuation or slightly increased attenuation compared with adjacent soft tissue structures (eg, skeletal muscles). 3,6 No associated calcification is seen.…”

Section: Discussionmentioning

confidence: 99%

“…3 Furthermore, CT was not only helpful for making a correct diagnosis but also for guiding the biopsy of the cardiac mass and planning the radiation field for radiation treatment by delineating the extent of the disease. 18 The most significant disadvantage of CT is its use of ionizing radiation, an important consideration in imaging pediatric and young adult patients because of the potentially increased risk for developing neoplasms. [20][21][22] Although our patient was evaluated with CT because of the need for immediate evaluation of the patient's acute clinical symptoms of shortness of breath and tachycardia, we believe that magnetic resonance imaging, which can well characterize cardiac masses without associated ionizing radiation, should be considered as a first line imaging modality for evaluating cardiac masses, particularly in children and young adults in nonemergent situations.…”

Section: Discussionmentioning

confidence: 99%

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MDCT Imaging Findings of Extramedullary Granulocytic Sarcoma of the Heart

Tsai

Lee

2010

Journal of Thoracic Imaging

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Granulocytic sarcoma, also known as chloroma, is an uncommon tumor typically seen in patients with acute myelogenous leukemia (AML). Extramedullary cardiac involvement of granulocytic sarcoma is rare and there is a paucity of information regarding its multidetector computed tomography (MDCT) imaging appearance. We present a case of extramedullary granulocytic sarcoma of the heart detected on MDCT in a young adult male with AML. An understanding of how extramedullary granulocytic sarcoma of the heart appears on MDCT may decrease or prevent delays in diagnosing this uncommon, although important, complication from AML.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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MDCT Imaging Findings of Extramedullary Granulocytic Sarcoma of the Heart

Tsai

Lee

2010

Journal of Thoracic Imaging

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“…These reports account for one-third of the patients studied. In recent years this number has increased due to the prolonged periods of remission achieved through efficient chemotherapy [7].…”

Section: Discussionmentioning

confidence: 99%

Skeletal manifestations of granulocytic sarcoma (chloroma)

et al. 1991

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Skeletal manifestations of chloroma were reviewed in five patients. In four cases, a chloroma was the initial manifestation of a systemic disease. In the fifth, an elderly patient developed a bone lesion during a blastic crisis while under treatment for chronic myelogenous leukemia. Two patients presented with lytic lesions of the ribs, two with lytic lesions of the femur, and one with a predominantly sclerotic lesion of the scapula. The laboratory findings in two patients were within normal limits. All lesions were confirmed by bone biopsy.

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“…A variety of radiographic findings caused by leukemic infiltration and its complications in the chest and abdomen have been described [1 -9J; however, there are few reports dealing with computed tomographic (CT) findings [10][11][12]. We reviewed our experience over a 4 year period with all CT scans in leukemic patients.…”

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confidence: 99%