Computed tomography findings and surgical outcomes of dermoid sinuses: a case series

Appelgrein, Carla; Hosgood, Giselle; Reese, SL

doi:10.1111/avj.12521

Cited by 8 publications

(24 citation statements)

References 12 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The use of CT and/or MRI for the diagnosis and assessment of dermoid sinuses has been described in dogs and cats. MRI seems to be superior to other imaging modalities [2] [21]. All advanced diagnostic imaging modalities may fail to show clearly the exact path or termination of the sinus tract.…”

Section: Discussionmentioning

confidence: 99%

Dermoid sinus in the perirectal fossa of a Siamese cat with involvement of the vaginal wall

Habenbacher

Adrian²,

Nelissen

2019

Tierarztl Prax Ausg K

View full text Add to dashboard Cite

A 2.5-year-old spayed female Siamese cat was presented with a recurrent exudative wound in the right perirectal fossa. Clinical examination at presentation revealed a 1 cm long open wound with purulent discharge in the right perirectal fossa but was otherwise unremarkable. A computed tomography contrast-enhanced study showed a tracking sinus which could be traced from the right dorsolateral perianal region right up to the level of the vagina. Surgical exploration was performed from the perirectal region. The intermuscular sinus tract, which formed a cystic structure and connected to the vaginal wall, was en bloc excised. Histopathological examination confirmed the diagnosis of a dermoid sinus in the perirectal fossa with vaginal infiltration. To the authors’ knowledge, this is the first case report in the veterinary literature of the successful surgical management of a dermoid sinus in the perianal region connected to the vaginal wall in a cat.

show abstract

Section: Discussionmentioning

confidence: 99%

Dermoid sinus in the perirectal fossa of a Siamese cat with involvement of the vaginal wall

Habenbacher

Adrian²,

Nelissen

2019

Tierarztl Prax Ausg K

View full text Add to dashboard Cite

show abstract

“…They have been noted in several dog breeds (OMIA 000272‐9615), including the boxer, Dachshund, English springer spaniel, French bulldog (Figure 1d,e; images are of a different unpublished French bulldog case), golden retriever, Siberian husky, shih tzu, and Yorkshire terrier (Barrios et al, 2014; Cornegliani & Ghibaudo, 1999; Kopke et al, 2019; Motta et al, 2012; Ployart, Doran, Bomassi, Bille, & Libermann, 2013; Pratt et al, 2000; Sturgeon, 2008). Dermoid sinus is most commonly found as an inherited condition in the Rhodesian ridgeback and Thai ridgeback dog breeds (Appelgrein et al, 2016; Mann & Stratton, 1966; Salmon Hillbertz, 2005). In these breeds, the characteristic hair ridge down the back of animals is caused by a large duplication of a region encompassing several genes; fibroblast growth factor 3, fibroblast growth factor 4, fibroblast growth factor 19 and oral cancer overexpressed 1 (Salmon Hillbertz et al, 2007).…”

Section: Spinal Ntdsmentioning

confidence: 99%

“…A range of NTD phenotypes exist (Table 1, Figure 1, Supporting Information Figure S1) and their effects can range from serious to benign (Botto, Moore, Khoury, & Erickson, 1999; Copp & Greene, 2010; Song et al, 2016). NTDs are recognized in several domestic species including dogs (Appelgrein, Hosgood, & Reese, 2016; Lazzerini et al, 2017; Wilson, Kurtz, Leipold, & Lees, 1979), cats (Lyons et al, 2016; Piummer, Bunch, Khoo, & Spaulding, 1993; Tamura et al, 2017), cattle and sheep (Adalsteinsson & Basrur, 1984; D. Y. Cho & Leipold, 1977; Kohli & Naddaf, 1998; Windsor, Kessell, & Finnie, 2011), pigs (I.‐C. Cho et al, 2015; Hughes & Hart, 1934; Mulley & Edwards, 1984; Wijeratne, Beaton, & Cuthbertson, 1974) and horses (A. M. Buck & Hunt, 2019; Van Hoogmoed, Yarbrough, Lecouteur, & Hornof, 1999) (Table 2).…”

Section: Introductionmentioning

confidence: 99%

Comparison of inherited neural tube defects in companion animals and livestock

Zarzycki

Thomas

Mazrier

2020

Birth Defects Research

View full text Add to dashboard Cite

Neural tube defects (NTDs) are congenital malformations resulting from the improper or incomplete closure of the neural tube during embryonic development. A number of similar malformations of the protective coverings surrounding the central nervous system are also often included under this umbrella term, which may not strictly fit this definition. A range of NTD phenotypes exist and have been reported in humans and a wide range of domestic and livestock species. In the veterinary literature, these include cases of anencephaly, encephalocele, dermoid sinus, spina bifida, and craniorachischisis. While environmental factors have a role, genetic predisposition may account for a significant part of the risk of NTDs in these animal cases. Studies of laboratory model species (fish, birds, amphibians, and rodents) have been instrumental in improving our understanding of the neurulation process. In mice, over 200 genes that may be involved in this process have been identified and variant phenotypes investigated. Like laboratory mouse models, domestic animals and livestock species display a wide range of NTD phenotypes. They remain, however, a largely underutilized population and could complement already established laboratory models. Here we review reports of NTDs in companion animals and livestock, and compare these to other animal species and human cases. We aim to highlight the potential of nonlaboratory animal models for mutation discovery as well as general insights into the mechanisms of neurulation and the development of NTDs.

show abstract

“…Dane piśmiennictwa dotyczące zatoki skórzastej są liczne, jakkolwiek duża część publikacji pochodzi sprzed wielu lat. W nowszych publikacjach uwagę zwracają niosące wiele informacji tabele podsumowujące dotychczasowy dorobek wielu lekarzy weterynarii (14,22) lub tylko własny (1,11) w dziedzinie rozpoznawania i leczenia zatok skórzastych w różnych miejscach ich lokalizacji i u różnych ras psów i kotów. Wspomnieć należy, że poza psami to zaburzenie występuje także u innych gatunków zwierząt, na przykład wspomnianych wyżej kotów (11), ale także u bydła (2), owiec (20) kóz (7) i wielbłądów (19).…”

Section: Omówienieunclassified

Triple dermoid sinus in sacro-caudal region in Rhodesian Ridgeback dog.

Sterna¹,

Sobczak-Filipiak²,

MIGDALSKA³

et al. 2019

Medycyna Weterynaryjna

View full text Add to dashboard Cite

The aim of this report is to describe a case of a triple dermoid sinus in the sacro-caudal region in an 11-month-old Rhodesian Rhidgeback dog. A clinical examination of the patient revealed a dermoid sinus in the sacro-caudal region. Neurological examination did not show any abnormalities. A blood test and a radiological examination were performed, but the owner refused to perform an MRI. A decision about surgical treatment was made. Two smaller lesions, located 2 cm and 4 cm caudally to the first one, were discovered during skin shaving. The skin around the lesions looked smoother and less pigmented than in the other parts of the body. All three lesions were resected up to the spinous process top or the supraspinous ligament. Histopathological examination showed a typical anatomy of the sinuses and anatomical changes in the skin between them: thinner epidermis and an abnormal shape of hair follicles. In the soft tissue between the ends of the sinus lumina and the supraspinous ligament there were no adnexal structures, such as hair or hair follicles. The sinus type was classified as IIIa. The surgical wound healed without complications. The owner was contacted 14 days and 6 months after surgery, and no signs of complications, pain or gait abnormalities were reported. Dermoid sinus diagnosis is based on medical history, clinical examination and diagnostic imaging. Computed tomography and magnetic resonance imaging are regarded as the most valuable. In many cases, however, their results are inconsistent with those of intraoperative exploration, for example, when a fibrous strand cannot be seen or the depth of the sinus has been inaccurately assessed. Often the depth and type of the dermoid sinus can be exactly assessed only by surgical exploration, so in some cases advanced imaging techniques can be omitted. The most commonly described location of a dermoid sinus is the cervical segment, with multiple lesions present. Only one case of a double dermoid sinus in the sacro-caudal section has been described in the literature. To our knowledge, a triple dermoid sinus at this location and skin anatomy changes in the dorsal medial line between sinuses have not yet been reported.

show abstract

Computed tomography findings and surgical outcomes of dermoid sinuses: a case series

Abstract: Preoperative CT facilitated the diagnosis of a dermoid sinus and directed surgical planning; however, careful dissection beyond the nuchal ligament is imperative for complete excision.

Cited by 8 publications

References 12 publications

Dermoid sinus in the perirectal fossa of a Siamese cat with involvement of the vaginal wall

Dermoid sinus in the perirectal fossa of a Siamese cat with involvement of the vaginal wall

Comparison of inherited neural tube defects in companion animals and livestock

Triple dermoid sinus in sacro-caudal region in Rhodesian Ridgeback dog.

Contact Info

Product

Resources

About