Abstract:Chagas disease is caused by the protozoan Trypanosoma cruzi and is widely distributed throughout Latin America. Because it is a pathology neglected by the pharmaceutical industry and because existing drugs have low efficacy and several side effects, interest in new drugs has been increasing. Due to the necessity of the discovery of new structures, the objective of this work was to relate the biological activity of natural and semi-synthetic aromatic compounds, inhibitors of glyceraldehyde 3-phosphate dehydroge… Show more
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