Computational model of the fluid dynamics in systemic-to-pulmonary shunts

Migliavacca, Francesco; Dubini, Gabriele; Pennati, Giancarlo; Pietrabissa, Riccardo; Fumero, R.; Hsia, Tain‐Yen; Leval, Marc R. de

doi:10.1016/s0021-9290(99)00219-5

Cited by 54 publications

(44 citation statements)

References 20 publications

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“…Flow of non-Newtonian fluid in a curved pipe is approximated as a quadratic function of Q(t) [11,12]. The instantaneous pressure drop across the shunt is described by:…”

Section: Pressure Drop Across the Shuntmentioning

confidence: 99%

Norwood procedure with non-valved right ventricle to pulmonary artery shunt improves ventricular energetics despite the presence of diastolic regurgitation: a theoretical analysis

et al. 2011

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When the Norwood procedure is conducted for the hypoplastic left heart syndrome using a non-valved right ventricle (RV) to pulmonary artery (PA) shunt, diastolic regurgitation from PA to RV may have an adverse effect on postoperative hemodynamics. In this study, we examined the impact of the diastolic regurgitation on ventricular energetics by computational analysis using a combination of a time-varying elastance chamber model and a modified three-element Windkessel vascular model. This study revealed that use of the valved or non-valved RV-PA shunt eliminated pulmonary over-circulation which was observed when using the systemic to pulmonary artery shunt (modified Blalock-Taussig shunt). Although the valved RV-PA shunt improved pulmonary blood supply and consequently increased pulmonary artery flow and oxygen saturation compared to the non-valved RV-PA shunt, the non-valved RV-PA shunt improved ventricular energetics in spite of the presence of PA to RV regurgitation.

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“…Flow of non-Newtonian fluid in a curved pipe is approximated as a quadratic function of Q(t) [11,12]. The instantaneous pressure drop across the shunt is described by:…”

Section: Pressure Drop Across the Shuntmentioning

confidence: 99%

Norwood procedure with non-valved right ventricle to pulmonary artery shunt improves ventricular energetics despite the presence of diastolic regurgitation: a theoretical analysis

et al. 2011

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“…These findings do not clarify whether this difference could be due to the geometry of the anastomosis itself. In a previous study from our laboratory (Migliavacca et al, 2000b), we reported the changes in pressure differences at the proximal and distal anastomoses with altered configurations of the MBTS shunt. For the CS configuration, a different model with a longer conduit was also built (Fig.…”

Section: Article In Pressmentioning

confidence: 99%

Multiscale modeling of the cardiovascular system: application to the study of pulmonary and coronary perfusions in the univentricular circulation

Laganà

Balossino

Migliavacca

et al. 2005

Journal of Biomechanics

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125

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“…Currently, the STS anastomosis is also used in the modified BT shunt. Although, many academic papers discuss the modified BT shunt, such as the effects of shunt diameter, curvature and angle, 6 …”

Section: Introductionmentioning

confidence: 99%

Hemodynamic Effects of the Anastomoses in the Modified Blalock–taussig Shunt: A Numerical Study Using a 0d/3d Coupling Method

Zhao

Liu

Ding

et al. 2015

J. Mech. Med. Biol.

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The modified Blalock-Taussig (BT) shunt is a palliative surgery which can help the tetralogy of Fallot (TOF) patient increase the blood oxygen saturation by interposing a systemic-topulmonary artery shunt. Two typical anastomotic shapes are frequently used in clinical practice: the end-to-side (ETS) and the side-to-side (STS) anastomosis. This paper examines the hemodynamic influence of the anastomotic shape in the modified BT shunt. Three models with different anastomotic shapes were reconstructed. The ETS anastomoses were applied in the first model. For the innominate artery (IA) and the pulmonary artery (PA) in the second model, the ETS and the STS anastomosis were applied, respectively. Finally, the STS anastomoses were applied in the third model. The 0D/3D coupling method was used to perform a numerical simulation by coupling the three-dimensional (3D) artery model with a zerodimensional (0D) lumped parameter model for the cardiovascular system. The simulation results showed that the perfusion into the left and right PA in Model 1 was unbalanced. Swirling flow appeared in the shunt in Model 3, but the shunt flow rate in Model 3 was lower. The ETS anastomosis at the PA may cause unbalanced blood perfusion into the left and right PA. Conversely, the STS anastomosis can make the blood perfusion more balanced. Otherwise, ¶ Corresponding author.the STS anastomosis at the IA could generate a swirling flow in the shunt which may provide a better hemodynamic environment while decreasing the pulmonary perfusion.

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Computational model of the fluid dynamics in systemic-to-pulmonary shunts

Cited by 54 publications

References 20 publications

Norwood procedure with non-valved right ventricle to pulmonary artery shunt improves ventricular energetics despite the presence of diastolic regurgitation: a theoretical analysis

Norwood procedure with non-valved right ventricle to pulmonary artery shunt improves ventricular energetics despite the presence of diastolic regurgitation: a theoretical analysis

Multiscale modeling of the cardiovascular system: application to the study of pulmonary and coronary perfusions in the univentricular circulation

Hemodynamic Effects of the Anastomoses in the Modified Blalock–taussig Shunt: A Numerical Study Using a 0d/3d Coupling Method

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