In 2004, at the request of the Department of Energy, Sandia National Laboratories (Sandia) prepared a report, "Guidance on the Risk and Safety Analysis of Large Liquefied Natural Gas (LNG) Spills Over Water". That report provided a framework for assessing hazards and identifying approaches to minimize the consequences to people and property from an LNG spill over water. The report also presented the general scale of possible hazards from a spill from 125,000 m 3 to 150,000 m 3 class LNG carriers, at the time the most common LNG carrier capacity.Because of the increasing size and capacity of many new LNG carriers, the Department of Energy requested that Sandia assess the general scale of possible hazards for a breach and spill from newer LNG carriers with capacities up to 265,000 m 3 . Building on the research and analyses presented in the 2004 report, Sandia reassessed emerging accidental and intentional threats and then conducted detailed breach analyses for the new large LNG carrier designs. Based on the estimated breach sizes, breach locations, and LNG carrier configurations, we estimated LNG spill rates and volumes and conducted thermal hazard and vapor dispersion analyses. This report summarizes the different analyses conducted, the expected range of potential hazards from a large LNG carrier spill over water, and risk management approaches to minimize consequences to people and property from such a spill.