Compressed Tablets—Average Weight

Instrumented Rotary Tablet Machines II

“…Thus, anything which causes more uniform filling of the dies should produce a more uniform compressional force impulse picture. Becausc the finer mesh particles of direct compaction mixtures fill the dies more uniformly than the coarser materizl of thr conventioIra1 gratiulatioua, inore uriiforni compressional force impulse heights are observrd when the fornicr materials are compressed (8, [36][37][38]. (Scr Pigs.…”

“…Brakc also suggested that hardness and disintcgration might be corrddtcd with the compressional force used to prepare the tablets (2). Thus, anything that can be done to insure compression of 125 equal die fills at uniform and reproducible forcc levels will contribute greatly to the production of tablets which are uniform within a lot and from lot to lot (7,8,11,31,36,37,43,44).…”

“…Thus, the IRTM provided an instantaneous and continuous indication of the relative flowability of a tableting material in contrast to tht more timeconsuming method of weighing a representative number of individual tablets after a run has been finished (31,36,37,39,43,44).…”

Wood Products, Corncob, and Cellulose as Tablet Disintegrating Agents

“…Those of the "absorb moisture and swell" type are by far the most commonly employed in research and industry today (1)(2)(3)(4)(5)(6)(7)(8), and the present study is confined to this group.…”