Comprehensive MR angiography of the lower limbs: a hybrid dual-bolus approach including the pedal arteries

Schmitt, Rainer; Coblenz, G.; Cherevatyy, O.; Brunner, H R; Fröhner, S.; Wedell, E.; Karg, G.; Christopoulos, Georgios

doi:10.1007/s00330-005-2852-4

Cited by 24 publications

(1 citation statement)

References 37 publications

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“…However, previous reports suggest that the 10-minute interval that we kept between the two examinations is sufficient for contrast equilibration [2, 7, 28]. Because subtraction images were obtained, in our experience, venous contamination from the first study was not a degrading factor in the images.…”

Section: Discussionmentioning

confidence: 61%

Time-Resolved MR Angiography of the Legs at 3 T Using a Low Dose of Gadolinium: Initial Experience and Contrast Dynamics

Sandhu

Rezaee

Jesberger³

et al. 2012

American Journal of Roentgenology

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OBJECTIVE This article describes our initial clinical experience with time-resolved MR angiography (MRA) of the legs using the time-resolved imaging with stochastic trajectories (TWIST) technique with a half dose of gadolinium. MATERIALS AND METHODS Thirty-four patients underwent a TWIST examination of the legs at 3 T. Thirty-three patients also underwent a bolus-chase MRA examination in the same setting. Times elapsed between the start of contrast injection and the appearance of contrast material (tA) and peak enhancement of the arteries in the legs (tB) were analyzed. The number of patients with examinations affected by venous contamination was determined. The differences in tA and tB between cases in which venous contamination was present or absent were evaluated using a two-tailed Student t test. RESULTS The TWIST technique using a half dose of gadolinium provided diagnostic-quality images of all patients. The mean tA was 35.5 ± 8.8 (SD) seconds (range, 17.8–60.4 seconds), and the mean tB was 59.1 ± 15.1 seconds (range, 31–98.8 seconds). Venous contamination was observed in bolus-chase MRA images of 52.9% of patients. The relationship between venous contamination and tA was not statistically significant (p = 0.13). The incidence of venous contamination was higher in patients with lower values of tB (p = 0.01). CONCLUSION The described low-dose clinical experience with TWIST and the contrast dynamics information gained from this study could aid radiologists in planning protocols for leg MRA examinations.

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Section: Discussionmentioning

confidence: 61%

Time-Resolved MR Angiography of the Legs at 3 T Using a Low Dose of Gadolinium: Initial Experience and Contrast Dynamics

Sandhu

Rezaee

Jesberger³

et al. 2012

American Journal of Roentgenology

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MR angiography of the pedal arteries with gadobenate dimeglumine, a contrast agent with increased relaxivity, and comparison with selective intraarterial DSA

Kreitner¹,

Kunz²,

Herber³

et al. 2007

Magnetic Resonance Imaging

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Purpose:To compare gadobenate dimeglumine (Gd-BOPTA)-enhanced MR angiography (i.e., contrast-enhanced MRA [CE-MRA]) of the pedal vasculature with selective digital subtraction angiography (DSA) in patients with peripheral arterial occlusive disease (PAOD). Materials and Methods:A total of 22 patients with PAOD were prospectively examined at 1.5T. For contrast enhancement, 0.1 mmol/kg body weight of Gd-BOPTA were applied. MRA consisted of dynamic imaging with acquisition of six consecutive data sets. Acquisition time for each data set was 24 seconds, voxel size was 1.0 ϫ 1.0 ϫ 1.3 mm 3 . A total of 20 out of 22 patient underwent selective DSA, two patients fineneedle DSA. DSA and MRA were performed within seven days. Image analysis was independently done by two observers with assessment of overall image quality, motion artifacts, detection of patent vessel segments of the distal calf and pedal vessels, and the number of patent metatarsal arteries. After four weeks, a consensus reading of DSA images was done. A second consensus reading of CE-MRA was performed after a further six weeks.Results: Consensus readings of MRA and DSA revealed higher image quality and fewer motion artifacts for MRA (P ϭ 0.021 and P ϭ 0.008, respectively, sign test); interobserver agreement was good ( ϭ 0.78) for image quality, and moderate ( ϭ 0.46) for motion artifacts. There were no differences between CE-MRA and DSA in detecting patent vessel segments with a high degree of agreement ( ϭ 0.89), and interobserver agreement for MRA was substantial ( ϭ 0.89). Significantly more vessels were assessed as partially occluded on DSA than on CE-MRA (P ϭ 0.004). There was a good agreement between DSA and CE-MRA for assessment of relevant vessel stenosis ( ϭ 0.61); interobserver agreement for MRA was good ( ϭ 0.65). CE-MRA detected significantly more patent metatarsal arteries than did DSA (P Ͻ 0.001). Conclusion:Gd-BOPTA-enhanced MRA is comparable to DSA for assessment of the pedal vasculature, and is able to delineate significantly more patent vessels without segmental occlusions and more metatarsal arteries than selective DSA.

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MRA of the Aorta and Peripheral Arteries

Tatlı

Yucel

2019

Contemporary Cardiology

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Comprehensive MR angiography of the lower limbs: a hybrid dual-bolus approach including the pedal arteries

Cited by 24 publications

References 37 publications

Time-Resolved MR Angiography of the Legs at 3 T Using a Low Dose of Gadolinium: Initial Experience and Contrast Dynamics

Time-Resolved MR Angiography of the Legs at 3 T Using a Low Dose of Gadolinium: Initial Experience and Contrast Dynamics

MR angiography of the pedal arteries with gadobenate dimeglumine, a contrast agent with increased relaxivity, and comparison with selective intraarterial DSA

MRA of the Aorta and Peripheral Arteries

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