2018
DOI: 10.3324/haematol.2018.196113
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Comprehensive molecular characterization of a heavy chain deposition disease case

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Cited by 9 publications
(6 citation statements)
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“…Sequences were analyzed using FinchTV software and aligned with MultAlin (http://multalin.toulouse.inra.fr/multalin/), and the l VJ rearrangement was determined using the IMGT/V-QUEST tool (http://imgt.org/). [16][17][18] High-throughput sequencing on Illumina MiSeq sequencer…”
Section: Topo Cloning and Sequencingmentioning
confidence: 99%
“…Sequences were analyzed using FinchTV software and aligned with MultAlin (http://multalin.toulouse.inra.fr/multalin/), and the l VJ rearrangement was determined using the IMGT/V-QUEST tool (http://imgt.org/). [16][17][18] High-throughput sequencing on Illumina MiSeq sequencer…”
Section: Topo Cloning and Sequencingmentioning
confidence: 99%
“…Recently, immunofluorescence studies of bone marrow from HCDD patients revealed that clonal PC secrete both the pathogenic truncated HC and a non-toxic free LC. Although this LC does not deposit in tissues, it can be used as a surrogate marker of HC secretion and of the underlying clone activity [ 27 ]. A mouse model of HCDD has been generated by knock-in insertion of a human HC in the mouse kappa LC locus.…”
Section: Pathophysiologymentioning
confidence: 99%
“…Sequences were analyzed using FinchTV software and aligned with MultAlin (http://multalin.toulouse.inra.fr/multalin/) and the λ VJ rearrangement was determinated using IMGT/V-QUEST tool (http://imgt.org/). [15][16][17] High-Throughput sequencing on ROCHE 454 sequencer Transcripts were amplified using 5' RACE-PCR and consensus reverse primers hybridizing in λ constant exons as previously described 18,19 and sequenced on a 454 sequencer (Roche).…”
Section: Topo Cloning and Sequencingmentioning
confidence: 99%