Composition and <i>in vitro</i> antibacterial activity of essential oils from four <i>Satureja</i> species growing in Iran

Hadian, Javad; Akramian, Morteza; Heydari, Hassan; Mumivand, Hasan; Asghari, Behvar

doi:10.1080/14786419.2010.534734

Cited by 31 publications

(13 citation statements)

References 34 publications

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“…Many members of this genus have aromatic and medicinal properties. The leaves, stems, and flowers of some species are used for herbal teas and in local folk medicine to treat various diseases/maladies such as muscle pain, diarrhea, wounds, urinary tract infections, and gastroenteritis (Hadian et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Toxicity of essential oil ofSatureja khuzistanica:In vitrocytotoxicity and anti-microbial activity

Yousefzadi¹,

Riahi‐Madvar²,

Hadian³

et al. 2013

Journal of Immunotoxicology

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In nature, essential oils play an important role in the protection of the plants by exerting anti-bacterial, -viral, -fungal, -oxidative, -genotoxic, and free radical scavenging properties, as well as in some cases acting as insecticides. Several Satureja species are used in traditional medicine due to recognized therapeutic properties, namely anti-microbial and cytotoxic activities. The purpose of the present work was to determine the biologic activity of the essential oil of S. khuzistanica Jamzad (Lamiaceae) against four human cancer cell lines, as well as its inhibitory effects against a wide array (i.e. n = 11) of pathogenic bacteria and fungi. The essential oil was isolated by hydro-distillation and analyzed by GC-FID and GC-MS. Carvacrol (92.87%) and limonene (1.2%) were found to be the main components of the isolated oil. Anti-microbial activity of the essential oil was assessed using a disc diffusion method; an MTT cytotoxicity assay was employed to test effects of the oil on each cancer cell line. The oil exhibited considerable anti-microbial activity against the majority of the tested bacteria and fungi. The test oil also significantly reduced cell viability of Vero, SW480, MCF7, and JET 3 cells in a dose-dependent manner, with the IC50 values calculated for each cell type being, respectively, 31.2, 62.5, 125, and 125 μg/ml. Based on the findings, it is concluded that the essential oil of S. khuzistanica and its major constituents have a potential for further use in anti-bacterial and anti-cancer applications, pending far more extensive testing of toxicities in normal (i.e. primary) cells.

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Section: Introductionmentioning

confidence: 99%

Toxicity of essential oil ofSatureja khuzistanica:In vitrocytotoxicity and anti-microbial activity

Yousefzadi¹,

Riahi‐Madvar²,

Hadian³

et al. 2013

Journal of Immunotoxicology

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“…Films with the oil effectively inhibited micro-organisms were tested. The authors claimed that S. hortensis oil, as a natural antibacterial agent, can potentially be used in packaging in a wide range of food Ahanjan et al (2011aAhanjan et al ( , 2011b, Goudarzi et al (2011), Hadian et al (2012), and Pirbalouti et al (2010Pirbalouti et al ( , 2011aPirbalouti et al ( , 2011b) S. biflora Biavati et al (2004), Kan et al (2006), Kosar et al (2008), Menkovic et al (2007), , Oke et al (2009aOke et al ( , 2009b, Orhan et al (2011Orhan et al ( , 2012, Savikin et al (2010), Skocibusic and Bezic (2004), Stefanini et al (2006), and Tommasi et al (2009) …”

Section: Pharmacologymentioning

confidence: 99%

A pharmacological and phytochemical overview onSatureja

Tepe

Çilkiz

2015

Pharmaceutical Biology

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Context: Satureja (Lamiaceae) species are used as flavoring compounds in food, pharmaceutical, and cosmetic industries because of its sweetness and simple cultivation characteristics. They have traditionally been used as muscle pain relievers, tonic, and carminative agents to treat stomach and intestinal disorders such as cramps, nausea, indigestion, and diarrhea, due to their considerable phytochemical characteristics. Objective: This review evaluates some information published since 1989 on Satureja genus from a systematic perspective in terms of its pharmacological and phytochemical characteristics. Materials and methods: Web of Science, PubMed, Scopus, and Google Scholar databases were searched up to March 2014. ''Satureja'' was used as a research term without narrowing or limiting research elements. After obtaining all reports from database (a total number is about 637), the papers were carefully analyzed in order to find data related to the topic of this review. Results: In this review, 453 reports were used which were published between 1989 and 2014. The study was compiled into two sections (Pharmacology and Phytochemistry). In the pharmacology section, more than 50 different activities were studied. In the second section, in addition to other compounds and inorganic substances, volatiles, phenolic acids, and flavonoids were discussed. Discussion and conclusion: According to our contemporary information, Satureja species have been evaluated for their wide range of biological activities. However, a small part of these studies have been carried out on the active principles. Therefore, in the future, more studies should be carried out to identify responsible phytochemicals for the various activities.

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“…In central part of Iran, the local people have been used the aerial part of S. khuzistanica for medical practitioners, analgesic, antibacterial, and antifungal purposes [3][4][5]. The essential oil composition of S. khuzistanica and its biological activities have been studied comprehensively [2][3][4]. Nevertheless, there are a few reports on the phytochemical profile of nonvolatile constituents.…”

Section: Previous Studiesmentioning

confidence: 99%

“…Some of these species such as Satureja montana, S. atropatana and S. hortensis have been used as flavoring agents, herbal teas, and food additives [1,2]. In central part of Iran, the local people have been used the aerial part of S. khuzistanica for medical practitioners, analgesic, antibacterial, and antifungal purposes [3][4][5]. The essential oil composition of S. khuzistanica and its biological activities have been studied comprehensively [2][3][4].…”

Section: Previous Studiesmentioning

confidence: 99%

Monoterpene Flavonoid from Aerial Parts of Satureja khuzistanica

Davoodi¹,

Rustaiyan²,

Ebrahimi³

2018

Rec.Nat.Prod.

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Fractionation of methanolic extract of Satureja khuzistanica Jamzad by Sephadex LH-20 and reverse phase chromatography led to the isolation and purification of a new monoterpene flavonoid (1), as well as six previously detected flavonoid derivatives (2-6). The structure assignment has been performed by using 1D, 2D NMR, and high-resolution MS spectrometry. In addition, electronic circular dichroism (ECD) spectroscopy was used to reveal the absolute configuration of 1.

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Composition and in vitro antibacterial activity of essential oils from four Satureja species growing in Iran

Cited by 31 publications

References 34 publications

Toxicity of essential oil ofSatureja khuzistanica:In vitrocytotoxicity and anti-microbial activity

Toxicity of essential oil ofSatureja khuzistanica:In vitrocytotoxicity and anti-microbial activity

A pharmacological and phytochemical overview onSatureja

Monoterpene Flavonoid from Aerial Parts of Satureja khuzistanica

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