Composition and antioxidant activity of the polysaccharides from cultivated Saussurea involucrata

Yao, Lingyun; Zhao, Qingsheng; Xiao, Jie; Sun, Jian; Yuan, Xiaofan; Zhao, Bing; Su, Huiming; Niu, S M

doi:10.1016/j.ijbiomac.2011.11.012

Cited by 33 publications

(12 citation statements)

References 23 publications

(20 reference statements)

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“…The maximum per cent H 2 O 2 scavenging activity (41.05 ± 0.46%) was recorded in the methanolic leaf extract, and the minimum (39.75 ± 0.36%) in the aqueous leaf extract at 1 mg mL − 1 concentration of extracts. The same pattern in respect of antioxidant activity by DPPH assay was observed by Yao et al [67] from two polysaccharides (SCIP1-2 and CSIP2-3) isolated from Saussurea involucrata, and they reported 60.3% and 88.7% DPPH scavenging activity at a dose of 8 mg mL − 1 , respectively for the two polysaccharides. S. obvallata therefore contains more antioxidant potential compared to S. involucrata.…”

Section: Gc-ms Analyses Of Methanolic Extracts Of Saussurea Obvallatasupporting

confidence: 81%

Antioxidant, antimicrobial, and GC-MS profiling of Saussurea obvallata (Brahma Kamal) from Uttarakhand Himalaya

Semwal

Painuli

2019

Clin Phytosci

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Background: Saussurea obvallata (DC.) Edgew. (S. obvallata) is an endangered medicinal herb of the high altitude Himalayan region with immense cultural significance. This study is one of the first report of pharmacological evaluation and GC-MS analysis of methanolic extracts of leaves and flowers of S. obvallata.Methods: Total flavonoid content (TFC) and total phenolic content (TPC) were performed according to standard protocols. The antioxidant activities of both the extracts (methanol and aqueous) were examined using two complementary methods, namely diphenylpicrylhydrazyl (DPPH) and Hydrogen peroxide (H 2 O 2 ) assay. While, antimicrobial potential examined by using classical assays on pathogenic microbial strains along with appropriate controls of antimicrobial agents. Gas Chromatographic-Mass Spectrometric analyses of methanolic extracts of S. obvallata were performed for the identification of bioactive components. Statistical analysis was performed by using SPSS version 16.0. Results: The extracts of leaves and flowers of S. obvallata showed significant results for all pharmacological experiments. TPC was recorded from a range of 132.67 ± 0.17 to 358.67 ± 0.17 mg GAE gm − 1 dw while TFC was recorded from a range of 65.73 ± 1.55 to 326.88 ± 2.11 mg QE gm − 1 dw. Per cent DPPH free radical scavenging activity was recorded from a range of 29.25 ± 0.86 to 82.88 ± 0.48% whereas per cent H 2 O 2 free radical scavenging activity were recorded from a range of 39.75 ± 0.36 to 41.05 ± 0.46%. Antimicrobial activity was analyzed against four bacterial strains and three fungal strains. S. obvallata extracts showed fine zone of inhibition against Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus, but Escherichia coli showed resistant (in terms of lower zone) against the extract compared to three bacteria. In antifungal activity, extract showed maximum zone of inhibition against Candida glabrata followed by Candida albicans and Candida tropicalis. GC-MS analysis of methanolic extracts of leaves and flowers of S. obvallata showed the presence of 36 and 48 components, respectively, based on retention time (Rt), and area per cent.Conclusion: These findings confirm the traditional claims and contribute in providing promising baseline information for the pharmacological use of S. obvallata. Additional highly developed research is essential for isolation and identification of specific active components which are responsible for pharmacological properties of the plant.

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Section: Gc-ms Analyses Of Methanolic Extracts Of Saussurea Obvallatasupporting

confidence: 81%

Antioxidant, antimicrobial, and GC-MS profiling of Saussurea obvallata (Brahma Kamal) from Uttarakhand Himalaya

Semwal

Painuli

2019

Clin Phytosci

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“…CSIP1-2 was composed of glucose, galactose, xylose, rhamnose, arabinose and galacturonic acid with a molar ratio of 1.65:0.39: 0.06:8.33:1.76:40.43. CSIP2-3 was composed of glucose, galactose, xylose, rhamnose, arabinose and galacturonic acid with a molar ratio of 0.76:0.66:0.11:5.59:0.32:44.66 (Yao et al, 2012).…”

Section: Polysaccharidesmentioning

confidence: 99%

“…Multiple phytochemicals from S. involcurata were found to possess anti-oxidative pharmacological function. Polysaccharides of S. involucrata have demonstrated anti-oxidative effect by scavenging superoxide anions in nitroblue tetraazolium colorimetric method, DPPH, hydroxyl and ABTS radical scavenging assay and by inhibiting the formation of thiobarbituric acid reactant in mouse liver homogenate (Yao et al, 2012;Zheng et al, 1993). Research has also revealed a positive correlation between antioxidant activity and the amount of phenolic and flavonoid compounds in S. involucrata extracts, suggesting they could be the active constituents accounting for the antioxidant activity (Qiu et al, 2010;Wang et al, 2012b).…”

Section: Anti-oxidative and Anti-agingmentioning

confidence: 99%

Saussurea involucrata: A review of the botany, phytochemistry and ethnopharmacology of a rare traditional herbal medicine

Chik

Zhu

Fan

et al. 2015

Journal of Ethnopharmacology

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“…La capacidad antioxidante fue de 19.81 ± 1.11 mg/100g (calculado como % de captación de radicales libres del 2,2 difenil-1-picrilhidrazilo, DPPH). Yao et al (2012) demostraron que los polisacáridos de la maca tienen una alta actividad antioxidante y podrían constituir fuente de compuestos bioactivos.…”

Section: Caracterización Fisicoquímica De La Macaunclassified

Efecto de la temperatura y concentración de panela en la osmodeshidratación de maca asistido por ultrasonido

Vegas

Baltazar

2021

Rev Ambient Comport Soc

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Resumen La presente investigación tuvo como objetivo determinar los valores óptimos de temperatura (30-60 ºC) y concentración de panela (30-60 % p/p), en la cinética de osmodeshidratación de cubos de maca variedad amarilla (Lepidium meyenii) asistido por ultrasonido (40 kHz). Se estableció la metodología de superficie de respuesta con un diseño factorial estadístico 2k + 2(k) + 3 puntos centrales, sometiendo las muesttras a tratamiento con ultrasonido y un testigo. Los resultados mostraron una pérdida máxima de agua de 53.57 y 24.56 % en los tratamientos con ultrasonido y sin movimiento, mientras que la máxima ganancia de sólidos fue de 18.61 y 9.01 % respectivamente. En cuanto a los coeficientes de difusividad, se obtuvo valores entre 2.51 – 4.74 x 10-10 m2/s para el agua y 1.16 – 2.20 x 10-10 m2/s para los sólidos en el tratamiento con ultrasonido y entre 1.10 – 2.35 x 10-10 m2/s para el agua y 0.90 – 1.70 x 10-10 m2/s para los sólidos en el tratamiento testigo. El análisis de varianza mostró un efecto significativ (p < 0.05 y R2 ≈ 1) por parte de las variables estudiadas de manera lineal, cuadrática e interaccionadas. Como conclusión se tiene que los máximos valores de coeficiente de difusividad tanto para el agua como en sólidos en el tratamiento con ultrasonido se obtuvo en concentraciones de panela entre 54 – 61 % p/p y temperatura 48-54 ºC y para el tratamiento testigo a concentraciones de panela de 50-56 % p/p y temperatura entre 46-52 ºC.

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Composition and antioxidant activity of the polysaccharides from cultivated Saussurea involucrata

Cited by 33 publications

References 23 publications

Antioxidant, antimicrobial, and GC-MS profiling of Saussurea obvallata (Brahma Kamal) from Uttarakhand Himalaya

Antioxidant, antimicrobial, and GC-MS profiling of Saussurea obvallata (Brahma Kamal) from Uttarakhand Himalaya

Saussurea involucrata: A review of the botany, phytochemistry and ethnopharmacology of a rare traditional herbal medicine

Efecto de la temperatura y concentración de panela en la osmodeshidratación de maca asistido por ultrasonido

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