Components and antibacterial activity of the roots of Salvia jaminiana

An easy and stereoselective rearrangement of an abietane diterpenoid into a bioactive microstegiol derivative

“…Most of the strains tested in this work were not used in the antibacterial activity studies on some abietanes reported previously (Kabouche et al, 2005;Ulubelen et al, 2000).…”

“…Microstegiol (1, Fig. 1) (Ulubelen et al, 1992) is a rearranged abietane isolated from several Labiatae plants belonging to the Salvia (Li et al, 2000;Topcu and Ulubelen, 1996;Ulubelen et al, 1992Ulubelen et al, , 1997 and Ajuga (Kö kdil et al, 2002) genera and it has shown pharmacological properties as an antileukemic, cytotoxic (Topcu et al, 2003) and antibacterial agent (Kabouche et al, 2005;Ulubelen et al, 2000). Surprisingly, only one total synthesis of the hydrocarbon framework of microstegiol (1) and its naturally occurring 3-oxo derivative (Chyu et al, 2005) has been reported until now (Taj et al, 2009).…”

Study on chemical composition and biological activities of essential oil and extract from Salvia pisidica

“…Methanolic extracts of S. cryptantha and S. multicaulis had also antimicrobial potential (Tepe et al, 2004). The acetone extract of S. jaminiana, containing the sterols campestanol, stigmasterol and sitosterol, and five known diterpenoids, ferruginol, cryptanol, 6,7-dehydroroyleanon, 6-hydroxysalvinolone and microstegiol, remarkably inhibited the growth of B. subtilis, S. aureus ATCC 25923 and Streptococcus a-hemolitic (Kabouche et al, 2005). Kamatou, Viljoen, van Vuuren, and van Zyl (2006) reported that the extract of S. chamelaeagnea showed good antibacterial activity against the four pathogens containing B. cereus, S. aureus, E. coli and K. pneumoniae.…”

Bioactive Properties of Eremostachys macrophylla Montbr. & Auch. Rhizomes Growing in Iran

“…19 Antioxidant, cytotoxic and antibacterial effects of fatty acids, steroids were confirmed previously. [25][26][27][28][29][30][31] Likewise, some polycyclic aromatic hydrocarbons and terpenoids have been reported for these bioactive properties. [32][33][34][35] Therefore, the potential biological efficacy of DCM extract may be related to the combination of these compounds and their synergies correlation with each other.…”