Abstract:A total of 302 patients with stage Ib and IIa cervical carcinoma were submitted to radical hysterectomy and lymphadenectomy during the period from 1980 to 1994. The morbidity rate was 37.5% and the mortality rate 0.6%. The most common intraoperative complications were injuries to the great pelvic vessels and the most frequent postoperative complications involved the urinary tract. The leading causes of morbidity were urinary infection (20.8%), bladder dysfunction (9.2%) and ureteral fistulas (2.9%). Although t… Show more
“…In our study, the only fistula occurred in a patient who had received 5000 cGy radiotherapy before radical surgery, and with continuous bladder drainage for 3 weeks there was spontaneous healing of the fistula. The incidence of urinary tract infection (UTI) in our series was 11% by 14 weeks after surgery and this was comparable to that reported by Cardosi [8] but less than the figure of 20% documented by Abrao [9]. Also, Chen reported a 14% urinary tract infection rate following radical surgery [10].…”
Background: This study has evaluated urinary tract injuries and dysfunction after Radical Hysterectomy (RH) performed in patients with cervical cancer and has compared the cystometric parameters and urinary complications occurring in these patients with those occurring in patients who had undergone Simple Hysterectomy (SH).
“…In our study, the only fistula occurred in a patient who had received 5000 cGy radiotherapy before radical surgery, and with continuous bladder drainage for 3 weeks there was spontaneous healing of the fistula. The incidence of urinary tract infection (UTI) in our series was 11% by 14 weeks after surgery and this was comparable to that reported by Cardosi [8] but less than the figure of 20% documented by Abrao [9]. Also, Chen reported a 14% urinary tract infection rate following radical surgery [10].…”
Background: This study has evaluated urinary tract injuries and dysfunction after Radical Hysterectomy (RH) performed in patients with cervical cancer and has compared the cystometric parameters and urinary complications occurring in these patients with those occurring in patients who had undergone Simple Hysterectomy (SH).
“…In addition to the aforementioned complications, genitourinary fistulas are also significant due to their clinical consequences following radical hysterectomies. The reported rate of fistulas has been as high as 30% [21], possibly due to the more extensive parametrial resection that was commonly performed. However, more recent studies have shown a decrease in the fistula rate to under 3% [18,19,22], consistent with our cohort's findings (2.7%).…”
Although bladder dysfunction is the most commonly reported complication after radical hysterectomy, there are other significant complications associated with cervical cancer surgery that have received less attention in the literature. This study aims to investigate the frequency of non-functional complications related to radical hysterectomy and identify significantly related risk factors associated with their occurrence.A retrospective study was conducted on consecutive patients diagnosed with early-stage cervical cancer who underwent radical hysterectomy at La Paz University Hospital between 2005 and 2019. The study collected data on intraoperative, short-term and long-term complications, and a multivariate analysis was performed to identify potential predictors of surgical complications. Of the 111 patients included in the study, 11.7% experienced intraoperative complications. Multivariate analysis indicated that the presence of microscopic parametrial involvement was significantly associated with an increased risk of intraoperative complications (Odds ratio (OR) = 16.7; 95% Confindent interval (CI): 1.4-195). Urological complications were the most common short-term complications, affecting 14.4% of the patients. On the other hand, lymphedema was the most frequent long-term complication, with a prevalence of 18%. In univariate analysis, the International Federation of Gynecology and Obstetrics (FIGO) stage tended to be associated (p = 0.05) with postoperative complications. Furthermore, the performance of selective sentinel lymph node biopsy instead of lymphadenectomy was associated with a reduced incidence of lymphedema, from 18% to 3.8%. While urological complications are the most common after radical hysterectomy, other complications, such as genitourinary fistula or lymphedema, while less frequent, are also significant due to their negative impact on patients' quality of life. Thus, an accurate preoperative diagnosis is essential to prevent surgical complications.
“…Regarding other complications secondary to radical hysterectomies, genitourinary stulas are also important due to their clinical consequences. The rate of stula has been reported to be up to 30% [22], probably due to the more extensive parametrial resection that was routinely performed in the past. The most recent studies showed a stula rate under 3% [18, 21,23,24], which is similar to what was found in our cohort (2.7%).…”
Purpose: Bladder dysfunction is the most frequent complication after radical hysterectomy. However, there are other relevant complications associated with cervical cancer surgery much less reported in literature. The aim of this study was to evaluate the frequency of non-functional complications associated with radical hysterectomy and to determine if there is any risk factor associated with their appearance. Methods: A retrospective study was conducted, including consecutive patients diagnosed with early-stage cervical cancer who underwent radical hysterectomy at La Paz University Hospital from January 2005 to December 2019. Data from intraoperative, short-term, and long-term complications were collected. A multivariate analysis was performed in order to identify potential predictors of surgical complications. Results: A total of 111 patients were included. Intraoperative complications occurred in 13(11.7%) women. Multivariate analysis showed a greater risk of intraoperative complications if microscopic parametrial involvement was present (OR=16.7; 95%CI 1.4-195). 41(36.9%) patients had any short-term postoperative complication, being urological the most frequent ones. Lymphedema was the most frequent long-term complication and occurred in 20(18%) patients. In short-term and long-term univariate analysis, TNM histological tumor stage was tended to be associated (p=0.07) to short-term postoperative complications, and FIGO stage was significatively associated (p=0.05) to long-term postoperative complications. Conclusion: Urological complications are the most frequent ones after radical hysterectomy. However, other less frequent complications such as genitourinary fistula or lymphedema are also important due to their impact on the quality of life of patients. We found that parametrial involvement in the postoperative pathological analysis was associated with higher intraoperative complications rate.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.