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Abstract

Background: This study has evaluated urinary tract injuries and dysfunction after Radical Hysterectomy (RH) performed in patients with cervical cancer and has compared the cystometric parameters and urinary complications occurring in these patients with those occurring in patients who had undergone Simple Hysterectomy (SH).

Prevalence of Urogynaecological Symptoms in Survivors of Cervical Cancer in a Tertiary Care Gynaecologic Oncology Clinic of a Developing Country

“…Surgery in the form of radical hysterectomy has its own set of complications such as reduced/absent bladder sensation and ureteric fistulae (and the same has been adequately explored by researchers. 3,4 Both Constipation and urinary dysfunction have been reported in earlier studies due to injury to the parasympathetic nerves during pelvic surgery. 3,[6][7] Women with cervical cancer frequently develop symptoms like hematuria and/or overactive bladder resulting from various causes including cystitis due to both direct and indirect effects of cancer and its treatments.…”

“…3,4 Both Constipation and urinary dysfunction have been reported in earlier studies due to injury to the parasympathetic nerves during pelvic surgery. 3,[6][7] Women with cervical cancer frequently develop symptoms like hematuria and/or overactive bladder resulting from various causes including cystitis due to both direct and indirect effects of cancer and its treatments. The major syndromes encountered in these women are increased susceptibility to infections due to both physical and immunologic effects of treatment, haemorrhagic cystitis caused by chemotherapeutic urothelial toxins and urinary problems caused by both acute and chronic effects of radiation therapy.…”

“…[4][5][6][7] Chemotherapy has widespread effects on various systems and specifically to lower urinary tract, can be a cause of haemorrhagic cystitis. [2][3][4] While assessing the need for specialist urogynaecological input in our patients, we noticed that contemporary literature available on morbidity burden of urinary symptoms is restricted only to very few specific conditions/complications. Surgery in the form of radical hysterectomy has its own set of complications such as reduced/absent bladder sensation and ureteric fistulae (and the same has been adequately explored by researchers.…”

“…Cystitis is seen usually as radiation doses approach 3000 cGy to the bladder. [1][2][3][4][5][6] This presents as accompanied by suprapubic tenderness, dysuria, urinary frequency and urgency Incontinence. As doses to the bladder approach more than 6000 cGy, acute hemorrhagic cystitis, chronic cystitis, fibrosis with decreased bladder capacity, and fistula formation may ensue.…”

“…As doses to the bladder approach more than 6000 cGy, acute hemorrhagic cystitis, chronic cystitis, fibrosis with decreased bladder capacity, and fistula formation may ensue. [1][2][3][4][5][6] The treatment of urinary incontinence in patients with prior radiation exposure and history of radical hysterectomy is particularly complicated especially for continuous incontinence of extraurethral origin viz fistula as surgical treatments can be compromised by the poor vascular supply to the tissues after radiation therapy. [4][5][6][7] Chemotherapy has widespread effects on various systems and specifically to lower urinary tract, can be a cause of haemorrhagic cystitis.…”