Complications of laparoscopic rectal cancer surgery

Climent, Marta; Martin, Seán T.

doi:10.20517/2574-1225.2018.62

Cited by 12 publications

(7 citation statements)

References 69 publications

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“…Besides, the usual risks of surgery such as major blood loss and infections, colectomy might lead to serious tissue damage causing leakage of the anastomosis. [12][13][14][15][16][17][18][19] It is also worth mentioning that the risk of fecal and urinary incontinence after radiation therapy is high. 5,[20][21][22][23][24][25] Another problem associated with radiotherapy and chemotherapy is tissue toxicity as both cancerous and healthy cells are affected.…”

Section: Introductionmentioning

confidence: 99%

<p>Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery System</p>

Wathoni

Nguyen

Rusdin

et al. 2020

DDDT

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Colorectal cancer is one of the most common cancer diseases with the increase of cases prevalence >5% every year. Multidrug resistance mechanisms and non-localized therapy become primary problems of chemotherapy drugs for curing colorectal cancer disease. Therefore, the enteric-coated nanoparticle system has been studied and proved to be able to resolve those problems with good performance for colorectal cancer. The highlight of our review aims to summarize and discuss the enteric-coated nanoparticle drug delivery system specific for colorectal cancer disease. The main and supporting literatures were collected from published research articles of journals indexed in Scopus and PubMed databases. In the oral route of administration, Eudragit pH-sensitive copolymer as a coating agent prevents the degradation of the nanoparticle system from the gastric fluid and releases drug to intestinal-colon track. Therefore, it provides a colon-specific targeting ability. Impressively, enteric-coated nanoparticles having a sustained release profile significantly increase the cytotoxic effect of chemotherapeutic drugs and achieve cell-specific target delivery. The enteric-coated nanoparticle drug delivery system represents an excellent modification to improve the effectiveness and performance of anticancer drugs for colorectal cancer disease in terms of the oral route of administration.

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Section: Introductionmentioning

confidence: 99%

<p>Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery System</p>

Wathoni

Nguyen

Rusdin

et al. 2020

DDDT

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“…The risk of erectile dysfunction in transabdominal repair of rectal prolapse has been partly attributed to injury to the periprostatic nerves that occurs during anterior mobilization of the rectum. The risk of ejaculatory disorder in other rectal surgeries is up to 60% [47, 48]. Men with rectal prolapse often have a deep rectovesical pouch that is likely to extend below the level of the nerves, minimizing the risk of damage to the periprostatic nerves [47].…”

Section: Discussionmentioning

confidence: 99%

“…The current review identified that sexual function is often poorly reported, with only 40% of papers commenting on sexual function either pre-or TA B L E 3 Morbidity and mortality reported for included studies. surgeries is up to 60% [47,48]. Men with rectal prolapse often have a deep rectovesical pouch that is likely to extend below the level of the nerves, minimizing the risk of damage to the periprostatic nerves [47].…”

Section: Discussion and Con Clus Ionmentioning

confidence: 99%

Outcomes for men undergoing rectal prolapse surgery – a systematic review

et al. 2023

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INTRODUC TI ON BackgroundExternal rectal prolapse (ERP) is defined as a protrusion of all layers of the rectal wall through the anal canal [1]. Factors that may contribute to the development of rectal prolapse include pelvic floor dysfunction, chronic straining, a deep pouch of Douglas and multiparity [1,2]. The condition is estimated to affect 0.5% of the population, with older, multiparous women predominantly affected [3,4].Men account for 10% of the rectal prolapses seen and treated [5][6][7].Rectal prolapse in men is much higher in countries such as Egypt, where it commonly affects younger patients, but the exact mechanism for this is not well known [8][9][10].Surgical management of ERP can be broadly divided into abdominal and perineal approaches [11]. Most of the published literature on rectal prolapse focuses on women, with little guidance on the management of rectal prolapse in men [12]. The perineal approach is often reserved for clinically comorbid and frail patients

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“…Furthermore, the consequences of failed endoscopic cure include consideration of the most hazardous and complicated forms of colorectal surgery, including permanent ostomy formation [41]. Patients with rectal lesions removed using a low or ultra-low anterior resection have an increased risk of incontinence (12%) [42] and sexual dysfunction (20-46%) [43], and a 10-20% risk of permanent stoma [44,45]. Low anterior resection has a 30-day morbidity and mortality of 25% and 6%, respectively [46].…”

Section: Special Considerationsmentioning

confidence: 99%

Endoscopic Management of Large Non-Pedunculated Colorectal Polyps

Cronin

Bourke

2023

Cancers

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Large non-pedunculated colorectal polyps ≥20 mm (LNPCPs) comprise approximately 1% of all colorectal polyps. LNPCPs more commonly contain high-grade dysplasia, covert and overt cancer. These lesions can be resected using several means, including conventional endoscopic mucosal resection (EMR), cold-snare EMR (C-EMR) and endoscopic submucosal dissection (ESD). This review aimed to provide a comprehensive, critical and objective analysis of ER techniques. Evidence-based, selective resection algorithms should be used when choosing the most appropriate technique to ensure the safe and effective removal of LNPCPs. Due to its enhanced safety and comparable efficacy, there has been a paradigm shift towards cold-snare polypectomy (CSP) for the removal of small polyps (<10 mm). This technique is now being applied to the management of LNPCPs; however, further research is required to define the optimal LNPCP subtypes to target and the viable upper size limit. Adjuvant techniques, such as thermal ablation of the resection margin, significantly reduce recurrence risk. Bleeding risk can be mitigated using through-the-scope clips to close defects in the right colon. Endoscopic surveillance is important to detect recurrence and synchronous lesions. Recurrence can be readily managed using an endoscopic approach.

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Complications of laparoscopic rectal cancer surgery

Cited by 12 publications

References 69 publications

<p>Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery System</p>

<p>Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery System</p>

Outcomes for men undergoing rectal prolapse surgery – a systematic review

Endoscopic Management of Large Non-Pedunculated Colorectal Polyps

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