Compliance with nutrition prescription improves outcomes in patients with unresectable pancreatic cancer

Dietary treatment of weight loss in patients with advanced cancer and cachexia: A systematic literature review

“…After excluding duplicate studies, and studies that did not meet the inclusion criteria based on reading title and abstract, 23 papers were selected for full-text examination. Eighteen papers were excluded; nine in which the target population was not clearly defined as patients with advanced cancer and/or treatment with curative intent was given [9,[14][15][16][17][18][19], four in which there was not given enough information to classify cachexia [20][21][22][23] and five in which the effect of other interventions than dietary counselling were evaluated [24][25][26][27][28]. The present review is thus based on two non-randomized studies and three RCT's.…”

“…They found that only 31% of the patients reported taking all of their prescribed drink. This may have had an devastating effect on the result, as it is demonstrated that maximum weight gain is dependent on full compliance [24]. ONS are often used in dietary intervention trials since they usually are nutritional complete and easy to use, nevertheless, compliance can be challenging.…”

A.S.P.E.N. Clinical Guidelines: Nutrition Support Therapy During Adult Anticancer Treatment and in Hematopoietic Cell Transplantation

“…[107][108][109][110][111][112][113][114][115][116][117] In addition to the effects of ω-3 fatty acids on prostaglandin synthesis and COX-2 inhibition (indomethicin 50 mg twice a day), they also seem to be effective in reducing proinflammatory cytokines in CCS. 102,103,108,110,114 Early studies of ω-3 fatty acids were performed in pancreatic cancer patients 102,105,[108][109][110][111][112]116 ; more recent studies have looked at other cancer types.…”

“…[107][108][109][110][111][112][113][114][115][116][117] In addition to the effects of ω-3 fatty acids on prostaglandin synthesis and COX-2 inhibition (indomethicin 50 mg twice a day), they also seem to be effective in reducing proinflammatory cytokines in CCS. 102,103,108,110,114 Early studies of ω-3 fatty acids were performed in pancreatic cancer patients 102,105,[108][109][110][111][112]116 ; more recent studies have looked at other cancer types. 103,104,106,107,113,115,117 Enteral ω-3 fatty acids appear to stabilize weight 109,110,[113][114][115] or decrease the rate of weight loss 102,105 in cancer patients, although this appears to occur with little or no increase in lean body mass.…”

Randomized trials in exocrine pancreatic cancer

“…Kwasy tłuszczowe omega-3 (n-3), w szczególności kwas eikozapentaenowy, mogą mieć właściwoś -ci antykachektyczne. Analiza testem porównań wielokrotnych zależności dawka -odpowiedź wskazuje, że przyjmowane suplementy kwasów tłuszczowych n-3 (kwas eikozapentaenowy) wpływają istotnie statystycznie na zwiększenie masy ciała, suchej masy mięśniowej oraz poprawę jakości życia [153,154]. Dotychczas przeprowadzono siedem badań z randomizacją nad zastosowaniem żywienia enteralnego wzbogaconego m.in.…”