Compliance with antimalarial chemoprophylaxis in German soldiers: a 6-year survey

Frickmann, Hagen; Schwarz, NG; Hu, Holtherm; Maaßen, Winfried; Vorderwülbecke, Florian; Erkens, Kay; Fischer, Moritz; Morwinsky, T; Rm, Hagen

doi:10.1007/s15010-013-0411-5

Cited by 11 publications

(14 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies about the relationships between CP compliance and other preventive measures against mosquito bites are contradictory. Whereas some studies showed no association [ 15 ] or even competition [ 16 ] with the use of personal protection measures, two other studies [ 17 , 18 ] reported that compliance with CP was positively associated with anti-mosquito measures, in line with the present study. In addition to the traditional malaria-related behaviours, the present study also suggests that more compliant subjects are also more likely to believe in CP effectiveness and to follow recommendations for doxycycline-monohydrate pill taking: pills should be taken at the same time each day, concurrently with food.…”

Section: Discussionsupporting

confidence: 89%

“…Yet, the risk of contracting malaria was perceived as high during the mission and was associated with correct compliance. This result was expected and other military studies reported that perceived threat due to mosquitoes or high perceived risk of malaria were associated with CP compliance [ 18 , 20 , 21 ]. In civilian studies, it has also been shown that travellers who perceived themselves as being at high risk of developing malaria after returning home [ 22 ] or travellers in high-risk malaria-endemic areas who had correctly perceived the level of risk [ 15 ] were more often compliant with CP.…”

Section: Discussionsupporting

confidence: 80%

See 1 more Smart Citation

Factors associated with malaria chemoprophylaxis compliance among French service members deployed in Central African Republic

Créach¹,

Velut²,

Laval

et al. 2016

Malar J

View full text Add to dashboard Cite

BackgroundMalaria is a public health concern in the French armed forces, with 400–800 cases reported every year and three deaths in the past 2 years. However, lack of chemoprophylaxis (CP) compliance is often reported among service members. The aim of this study was to explore factors associated with CP compliance.MethodsA retrospective study (1296 service members) was carried out among troops deployed in Central African Republic. Determinants of CP were collected by self-questionnaire. Socio-demographic variables, behavioural characteristics, belief variables, operational determinants such as troops in contact (TIC) and number of nights worked per week and peer-to-peer reinforcement were studied. Relationships between covariates and compliance were explored using logistic regressions (outcome: compliance as a dummy variable).ResultsChemoprophylaxis compliance was associated with other individual preventive measures against mosquito bites (bed net use, OR (odds ratio) = 1.41 (95 % CI [1.08–1.84]), and insecticide on clothing, OR = 1.90 ([1.43–2.51]) and malaria-related behaviours (taking chemoprophylaxis at the same time every day, OR = 2.37 ([1.17–4.78]) and taking chemoprophylaxis with food, OR = 1.45 ([1.11–1.89])). High perceived risk of contracting malaria, OR = 1.59 ([1.02–2.50]), positive perception of CP effectiveness, OR = 1.62 ([1.09–2.40]) and the practice of peer-to-peer reinforcement, OR = 1.38 ([1.05–1.82]) were also associated with better compliance. No association was found with TIC and number of nights worked.ConclusionsThis study, which shows a positive relationship between peer-to-peer reinforcement and CP compliance, also suggests the existence of two main personality profiles among service members: those who seek risks and those who are health-conscious. Health education should be expanded beyond knowledge, know-how and motivational factors by using a comprehensive approach based on identification of health determinants, development of psychosocial skills and peer-to-peer reinforcement.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 80%

Factors associated with malaria chemoprophylaxis compliance among French service members deployed in Central African Republic

Créach¹,

Velut²,

Laval

et al. 2016

Malar J

View full text Add to dashboard Cite

show abstract

“…Further, in spite of training and education in basic hygienic measures that are implemented before deployment, soldiers may tend to noncompliance if the temptation of appealing local foods coincides with monotonous food in the field canteen or perhaps delivery problems during the first phases of deployment. A previous study described noncompliance problems with antimalarial chemoprophylaxis on deployment [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Surveillance of Food- and Smear-Transmitted Pathogens in European Soldiers with Diarrhea on Deployment in the Tropics: Experience from the European Union Training Mission (EUTM) Mali

Frickmann

Warnke²,

Frey

et al. 2015

BioMed Research International

View full text Add to dashboard Cite

Introduction. Since 2013, European soldiers have been deployed on the European Union Training Mission (EUTM) in Mali. From the beginning, diarrhea has been among the most “urgent” concerns. Diarrhea surveillance based on deployable real-time PCR equipment was conducted between December 2013 and August 2014. Material and Methods. In total, 53 stool samples were obtained from 51 soldiers with acute diarrhea. Multiplex PCR panels comprised enteroinvasive bacteria, diarrhea-associated Escherichia coli (EPEC, ETEC, EAEC, and EIEC), enteropathogenic viruses, and protozoa. Noroviruses were characterized by sequencing. Cultural screening for Enterobacteriaceae with extended-spectrum beta-lactamases (ESBL) with subsequent repetitive sequence-based PCR (rep-PCR) typing was performed. Clinical information was assessed. Results. Positive PCR results for diarrhea-associated pathogens were detected in 43/53 samples, comprising EPEC (n = 21), ETEC (n = 19), EAEC (n = 15), Norovirus (n = 10), Shigella spp./EIEC (n = 6), Cryptosporidium parvum (n = 3), Giardia duodenalis (n = 2), Salmonella spp. (n = 1), Astrovirus (n = 1), Rotavirus (n = 1), and Sapovirus (n = 1). ESBL-positive Enterobacteriaceae were grown from 13 out of 48 samples. Simultaneous infections with several enteropathogenic agents were observed in 23 instances. Symptoms were mild to moderate. There were hints of autochthonous transmission. Conclusions. Multiplex real-time PCR proved to be suitable for diarrhea surveillance on deployment. Etiological attribution is challenging in cases of detection of multiple pathogens.

show abstract

“…Malaria, travel-associated diarrhea as well as skin and sexually transmitted diseases are major health concerns on deployments in subtropical and tropical endemic settings [ 1 ]. Rapid diagnosis in case of suspected malaria is mandatory.…”

Section: Introductionmentioning

confidence: 99%

Comparison of two real-time PCR assays for the detection of malaria parasites from hemolytic blood samples — Short communication

Hagen

Hinz

Tannich

et al. 2015

EuJMI

View full text Add to dashboard Cite

We compared the performance of an in-house and a commercial malaria polymerase chain reaction (PCR) assay using freeze–thawed hemolytic blood samples.A total of 116 freeze–thawed ethylenediamine tetraacetic acid (EDTA) blood samples of patients with suspicion of malaria were analyzed by an in-house as well as by a commercially available real-time PCR.Concordant malaria negative PCR results were reported for 39 samples and malaria-positive PCR results for 67 samples. The in-house assay further detected one case of Plasmodium falciparum infection, which was negative in the commercial assay as well as five cases of P. falciparum malaria and three cases of Plasmodium vivax malaria, which showed sample inhibition in the commercial assay. The commercial malaria assay was positive in spite of a negative in-house PCR result in one case. In all concordant results, cycle threshold values of P. falciparum-positive samples were lower in the commercial PCR than in the in-house assay.Although Ct values of the commercial PCR kit suggest higher sensitivity in case of concordant results, it is prone to inhibition if it is applied to hemolytic freeze–thawed blood samples. The number of misidentifications was, however, identical for both real-time PCR assays.

show abstract

Compliance with antimalarial chemoprophylaxis in German soldiers: a 6-year survey

Cited by 11 publications

References 26 publications

Factors associated with malaria chemoprophylaxis compliance among French service members deployed in Central African Republic

Factors associated with malaria chemoprophylaxis compliance among French service members deployed in Central African Republic

Surveillance of Food- and Smear-Transmitted Pathogens in European Soldiers with Diarrhea on Deployment in the Tropics: Experience from the European Union Training Mission (EUTM) Mali

Comparison of two real-time PCR assays for the detection of malaria parasites from hemolytic blood samples — Short communication

Contact Info

Product

Resources

About