Compliance Rate of Surgical Antimicrobial Prophylaxis and its Association with Knowledge of Guidelines Among Surgical Residents in a Tertiary Care Public Hospital of a Developing Country

Abstract

Introduction Surgical antimicrobial prophylaxis (SAP) means the administration of antibiotics in surgical practice, and it reduces the likelihood of surgical site infections (SSIs). Inappropriate SAP practice regarding the prescription, timing, and duration of antibiotic use prolongs the hospital stay of patients, increases patient morbidity (by exposing them to the adverse effects of antibiotics), promotes bacterial resistance, and puts an economic burden on health care. While developed countries regularly monitor and revise their SAP protocols, there are only a few such researches in developing countries, which is a major setback to proper surgical care. Objectives of the study This study aims to compare the practice of SAP in a tertiary health care hospital of a developing country Pakistan, with internationally recommended protocols and evaluate the impact of knowledge of international guidelines on SAP practice. The results of the study will highlight important shortcomings in prophylactic practice in the hospital and help develop recommendations to improve SAP practice and ensure better surgical care for patients.

Gauging the Risk Factors for Asymptomatic Bacteriuria in Type-2 Diabetic Women: A Case-Control Study

“…However, screening and treatment of ASBU in diabetics has remained at the epicentre of a medical conundrum. Many long-term studies have established that routinely treating ASBU in all patients adversely affects patients' health (due to the associated side-effects of antibiotics) and promotes bacterial resistance, a major global medical challenge [ 12 , 14 - 15 ]. Thus, the current guidelines by the Infectious Diseases Society of America (IDSA) recommend against the screening and treatment of ASBU in diabetics [ 16 ].…”

<p>Optimizing compliance with surgical antimicrobial prophylaxis guidelines in patients undergoing gastrointestinal surgery at a referral teaching hospital in southern Iran: clinical and economic impact</p>

“…11 Despite this, studies have shown that optimal practice is not achieved in many hospitals, especially in developing countries. 12,13 The knowledge and attitudes of surgeons about appropriate SAP are important factors in the implementation of guidelines. It is necessary for hospital administrators and institutional quality-improvement departments to provide approaches to reduce such outcomes of antibiotic overuse as increased antibiotic resistance and higher financial costs to hospitals.…”

Exploring Antimicrobial Resistance in Agents Causing Urinary Tract Infections at a Tertiary Care Hospital in a Developing Country

“…The increasing resistance of E.coli towards broad-spectrum antibiotics like nitrofurantoin is of great concern and demands the need for appropriate antibiotic use according to the recommended guidelines. As there is no strict adherence to antibiotic stewardship, the clinicians tend to prescribe broad-spectrum antibiotics that contribute to increased antimicrobial resistance [17,18]. Researchers have recommended conducting quality improvement programs to ensure appropriate antibiotic use according to the proposed guidelines, especially in a developing country like ours.…”