Compliance of energy-dense, small volume oral nutritional supplements in the daily clinical practice on a geriatric ward — An observational study

Guerra

Am J Alzheimers Dis Other Demen

et al. 2017

This study aims to evaluate the impact of oral nutritional supplementation (ONS) and a psychomotor rehabilitation program on nutritional and functional status of community-dwelling patients with Alzheimer's disease (AD). A 21-day prospective randomized controlled trial was conducted and third intervention group performed a psychomotor rehabilitation program. Patients were followed up for 180 days. Mean (standard deviation) score of Mini Nutritional Assessment (MNA) increased both in the nutritional supplementation group (NSG; n = 25), 0.4 (0.8), and in the nutritional supplementation psychomotor rehabilitation program group (NSPRG; n = 11), 1.5 (1.0), versus -0.1 (1.1) in the control group (CG; n = 43), P < .05. Further improvements at 90-day follow-up for MNA in NSG: 1.3 (1.2) and NSPRG: 1.6 (1.0) versus 0.3 (1.7) in CG ( P < .05) were observed. General linear model analysis showed that the NSG and NSPRG ▵MNA score improved after intervention, at 21 days and 90 days, was independent of the MNA and Mini-Mental State Examination scores at baseline ( Ps > .05). The ONS and a psychomotor rehabilitation program have a positive impact on long-term nutritional and functional status of patients with AD.

supporting

confidence: 77%

Impact of Nutritional Supplementation and a Psychomotor Program on Patients With Alzheimer’s Disease

Guerra

Am J Alzheimers Dis Other Demen

et al. 2017

“…Enteral nutrition is an effective strategy for treating and avoiding malnutrition and is given as an oral nutritional supplement (ONS) when the patient is able to take it orally. A positive correlation has been reported between the compliance and energy density of ONS [12][13].…”

Section: Discussionmentioning

confidence: 78%

“…For patients who are unable to take enough nutritional supplements orally, they are fed using an enteral tube into the stomach or small intestine [9]. The energy density of commercialized formulations is approximately in the range of 0.5-2.4 kcal/mL [9,12]. Enteral nutrition is an effective strategy for treating and avoiding malnutrition and is given as an oral nutritional supplement (ONS) when the patient is able to take it orally.…”

Section: Discussionmentioning

confidence: 99%

Effect of a Novel, Energy-Dense, Low-Volume Nutritional Food in the Treatment of Superior Mesenteric Artery Syndrome

Akashi

Hashimoto

Funakoshi³

2021

Cureus

Superior mesenteric artery syndrome (SMAS) is an intermittent or persistent passage obstruction that occurs in the third portion of the duodenum between the aorta and the superior mesenteric artery. After symptoms stabilize, the nutritional intake is started by ingesting a small amount. Recently, an energy-dense, lowvolume nutritional food, Terumeal uplead ® (Terumo Corporation, Tokyo, Japan) with an energy density of 4.0 kcal/mL, was launched. We report a case of a postoperative SMAS patient who was successfully treated using Terumeal uplead ® through gastrostomy. An 83-year-old man who developed adhesive intestinal obstruction underwent right hemicolectomy, lysis of adhesion, and partial small bowel resection. Gastric distension persisted after surgery; thus, gastrostomy was performed for decompression and enteral nutrition on the 21st postoperative day, and enteral feeding was started on the 23rd postoperative day. However, fluoroscopy showed obstruction in the third portion of the duodenum, which was considered to be SMAS. To reduce the administration volume, enteral nutrition was replaced with Terumeal uplead ® from the 28th postoperative day (intermittent administration thrice a day, 300 mL, 1,200 kcal per day). From the 34th postoperative day, the gastrostomy tube was clamped for two hours after administration, and no drainage was observed. Oral intake was resumed from the 36th postoperative day, and it was used in combination with enteral nutrition. Three months later, the patient was discharged home and continued oral ingestion with occasional decompression from the gastrostomy tube. Thus, Terumeal uplead ® may be useful during the conservative treatment of SMAS by initiation with small amounts.

“…Therefore, the mixed-effects model was employed to account for within-patient correlation introduced by repeated measurements. This model is often used to correct for individual patient differences in repeated measures [23,24]. Fig 3 shows that the fitting of the model to data is fairly good.…”

Section: Plos Onementioning

confidence: 94%

Nutritional status and activities of daily living in patients with Parkinson’s disease

et al. 2021

Patients with Parkinson’s disease are often frail and likely to be malnourished. Several studies have reported the adverse effects of malnutrition on functional outcomes; however, the association between nutritional status and activities of daily living is unclear among patients with Parkinson’s disease. This study aimed to investigate the relationship between nutritional status and activities of daily living in patients with Parkinson’s disease. We conducted a retrospective cohort study with the data of 124 patients who were consecutively admitted to a rehabilitation hospital in Japan, among whom the data of 61 patients were included in the analyses. The Controlling Nutritional Status score was used to measure the nutritional status of the participants, and the motor subdomain of the Functional Independence Measure was used to assess the activities of daily living. Piecewise linear mixed-effects models were fitted to the data after adjusting for confounding factors. A poor nutritional status (i.e., Controlling Nutritional Status score >3) was significantly associated with a poor Functional Independence Measure gain, which was defined as difference in the score values of the Functional Independence Measures between discharge and admission. Our findings could aid in developing nutritional intervention programs for patients with Parkinson’s disease by employing the Controlling Nutritional Status score to improve their activities of daily living.