Compliance and Quality of Life in Patients on Prescribed Voice Rest

Rousseau, Bernard; Cohen, Seth M.; Zeller, Amy; Scearce, Leda; Tritter, Andrew G.; Garrett, C. Gaelyn

doi:10.1177/0194599810390465

Cited by 42 publications

(57 citation statements)

References 14 publications

(32 reference statements)

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“…Many factors have been proposed to explain the inconsistency in clinical practice, including beliefs about the physiology of vocal fold mucosal healing, lesion characteristics, surgical techniques, pre‐ and postoperative voice therapy, and patient adherence to treatment. Consequently, it appears that such variability may be due to the lack of empirical evidence to guide clinical management, poor patient adherence to treatment, and a negative impact of vocal restrictions on a patient's overall quality of life . These inconsistencies in clinical practice highlight the need for basic science investigations to investigate long‐standing assumptions regarding the physiology of vocal fold mucosal healing and responses to contemporary surgical treatments.…”

Section: Introductionmentioning

confidence: 99%

Biochemical basis of vocal fold mobilization after microflap surgery in a rabbit model

et al. 2013

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Objectives/Hypothesis To investigate phonation-related extracellular matrix (ECM) changes in the vocal fold lamina propria after microflap surgery using an in vivo rabbit phonation model. Study Design Prospective animal study. Methods Twenty-four New Zealand White rabbits were used in this study. Quantitative polymerase chain reaction and immunohistochemistry were used to investigate alterations in vocal fold ECM proinflammatory and profibrotic gene, and protein expression from a control group of animals receiving a microflap without phonation and a separate group of animals receiving experimentally induced phonation on postmicroflap days 0, 3, and 7. Results IHC demonstrated the highest concentration of CD45 in vocal folds on postoperative day 0. Staining for CD45 was absent by postoperative day 7, with no differences in CD45 staining between groups. Fibronectin gene expression increased significantly on postoperative day 3 in the control and experimentally induced phonation groups, with maximal staining of fibronectin around the microflap incision on postoperative day 7. No alterations in cyclooxygenase-2, interleukin-1β, and transforming growth factor-β1 gene expression were observed between groups. Conclusions Results of the present study revealed an acute inflammatory response in the vocal fold at the time of microflap (day 0) and up to 3 days post-microflap. By post-operative day 3, staining of CD45 positive cells decreased, with essentially no evidence of inflammation by post-operative day 7. With the end of the acute inflammatory response occurring around day 3, these data may provide support for mobilizing tissue after inflammation has subsided and the process of active tissue remodeling has ensued (days 3–7).

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Section: Introductionmentioning

confidence: 99%

Biochemical basis of vocal fold mobilization after microflap surgery in a rabbit model

et al. 2013

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“…4 They studied 84 patients undergoing voice rest for a variety of pathologies (of whom 59 were post-operative patients). The duration of voice rest ranged from 3 to 28 days, with no comments made about the type of voice rest prescribed.…”

Section: Strengths and Weaknesses Of The Studymentioning

confidence: 99%

Voice rest after vocal fold surgery: current practice and evidence

2013

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“…net werden [ 148 ] . Als eine pragmatische Variante hat sich die Empfehlung einer Kombination aus absoluter Stimmruhe und nachfolgender Stimmschonung erwiesen [ 149 ] .…”

Section: Postoperativer Wundheilungsverlaufunclassified

Fehler und Gefahren: Behandlung gutartiger Kehlkopferkrankungen

Bohlender

2013

Laryngo-Rhino-Otol

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More than half of patients who present with the symptom of hoarseness show benign vocal fold changes. The clinician should be familiar with modern diagnostic and therapeutic possibilities of benign vocal fold changes in order to ensure an optimal and individualized attention to voice patients. Basic knowledge of the etiology are provided for targeted phonosurgical or conservative therapy. This review article focuses on the diagnostic and therapeutic limitations and difficulties of treatment of benign vocal fold tumors, the management and prophylaxis of scarred vocal fold changes and the issue of unilateral vocal fold paralysis.

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Compliance and Quality of Life in Patients on Prescribed Voice Rest

Abstract: Given poor patient compliance and the significant impact of voice rest on QOL, further studies are warranted to examine the efficacy of voice rest and factors that may contribute to patient noncompliance with treatment.

Cited by 42 publications

References 14 publications

Biochemical basis of vocal fold mobilization after microflap surgery in a rabbit model

Biochemical basis of vocal fold mobilization after microflap surgery in a rabbit model

Voice rest after vocal fold surgery: current practice and evidence

Fehler und Gefahren: Behandlung gutartiger Kehlkopferkrankungen

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