Complexity from Simplicity: Tricyclic Aziridines from the Rearrangement of Pyrroles by Batch and Flow Photochemistry

Microflow photochemistry: UVC-induced [2 + 2]-photoadditions to furanone in a microcapillary reactor

“…We have instead applied inexpensive and flexible FEP tubing that was wrapped tightly around a Pyrex glass base and placed this simple unit inside a common Rayonet chamber reactor (‘outside-in’ irradiation). A different immersion well type FEP-capillary setup (‘inside-out’ irradiation) was recently reported but required a custom-built quartz tube [34]. Capillary-based reactors were originally developed for post-column photochemical derivatizations to enhance detection in HPLC [35–37] but are now commonly used in flow photochemical studies [5–9].…”

Design Consideration of Continuous-Flow Photoreactors

“…The device allowed to perform the synthesis of tricyclic aziridines 15,16 without degradation of the starting pyrroles, that was observed when using high-power medium pressure mercury lamps. 45 Thus, the reactants solution was flowed through the reactor by means of a valveless piston pump. The same reactor has been also used for the synthesis of dipeptides starting from nitrones.…”

Accelerated gas-liquid visible light photoredox catalysis with continuous-flow photochemical microreactors

“…With minor changes, it can easily be extended to other photocatalytic or photochemical protocols, e.g. homogeneous photocatalysis or UV mediated photochemistry [19][20] .…”

“…Chemical shifts for 1 H NMR spectra are reported relative to the TMS (0.0 ppm) or residual solvent peak, for 13 C NMR spectra relative to chloroform (77.13 ppm) and for 19 F NMR spectra relative to α,α,α-trifluorotoluene (-73.62 ppm). 9 | Open the oxygen gas supply, pressure regulator and set the MFC (Q G, Table 1).…”