Complexes of 3dn Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity

Abstract

Abstract:The chelating behavior of the thiosemicarbazone derivatives of 2-hydroxy-8-Rtricyclo [7.3.1.0. 2,7 ]tridecane-13-one (where R = H, CH 3 , C 6 H 5 ) towards Co(II), Ni(II) and Cu(II) has been investigated by elemental analysis, molar conductivity measurements, UV-VIS, IR, ESR spectroscopy and thermal studies. It was deduced from the experiments performed that the ligands coordinate to metal ions in different ways -neutral bidentate or mononegative bidentate -depending on the nature of R. Also, if metal acetates are used instead of metal chlorides, the ligands coordinate in a mononegative bidentate fashion, regardless of the nature of R or the thiosemicarbazone type ligand. The antimicrobial activity of the ligands and of the complexes towards samples of Acinetobacter boumanii, Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa was determined.

Mono- and binuclear copper(II) complexes of the bipyridine ligand: Structural, electrochemical and biological studies

“…complex [39]. For complex 5, a broad asymmetric band centered at 450 nm with a high-energy shoulder at 635 nm is consistent with the observed distorted square pyramidal geometry.…”

Synthesis and Antibacterial Studies of Metal Complexes of Cu(II), Ni(II) and Co(II) with Tetradentate Ligand

“…Due to their simplicity in preparation, diverse properties, medicinal, biochemical and industrial applications, the keen interest in the study of these compounds arose in the recent years. A number of metal coordination complexes of Schiff bases have been suggested as antibacterial, antifungal, cytotoxic, anti-inflammatory and cytostatic agents [4] [5] [6] [7]. In order to widen the scope of investigations on the coordination behavior of various donor …”

Synthesis, Characterization, Structural Interpretation, Biological Activity and DNA Cleavage Studies of 3-acyl 2-(2’hydroxy-5-X phenyl) Benzothiazoline Cu (II) Complexes

“…The electronic spectra of complexes showed low energy bands at 10437-16420 cm -1 and a strong high energy band at 23310-28328 cm-1. The low energy band in the position may be assigned to the transitions dx 2 -y 2 →dyz; dz 2 ; dxy [12][13] . The strong high energy band is assigned to metal→ligand charge transfer.…”