“…Hence, right ventricular contractility was not severely affected by the ventricular wall resection as the excised area was already akinetic before surgery. Furthermore, the resected coronary artery could be replaced by a venous graft, as already described in the literature, without influencing the contractility of the remained RV (14). The replacement of the resected tricuspid valve offered a stable structure to rebuild the right atrioventricular groove and the right atrial wall using a heterologous pericardium.…”
We present the case of a young woman without a medical history who presented with a giant right atrial, transtricuspid, and right ventricular mass and in a severe clinical state. Multimodal imaging raised the suspicion of primary cardiac angiosarcoma. Due to rapid hemodynamic and respiratory deterioration, we were forced to perform surgical removal of the mass with a concomitant reconstruction of the involved right heart structures, only 48 h after presentation. The postoperative course was uneventful, and the patient was discharged from the intensive care unit 2 days later. Radical surgical resection with reconstruction of the resected heart structures was the only possible salvage option for giant angiosarcoma, which led to hemodynamic instability. Followed by chemotherapy, this radical approach may prolong survival.
“…Hence, right ventricular contractility was not severely affected by the ventricular wall resection as the excised area was already akinetic before surgery. Furthermore, the resected coronary artery could be replaced by a venous graft, as already described in the literature, without influencing the contractility of the remained RV (14). The replacement of the resected tricuspid valve offered a stable structure to rebuild the right atrioventricular groove and the right atrial wall using a heterologous pericardium.…”
We present the case of a young woman without a medical history who presented with a giant right atrial, transtricuspid, and right ventricular mass and in a severe clinical state. Multimodal imaging raised the suspicion of primary cardiac angiosarcoma. Due to rapid hemodynamic and respiratory deterioration, we were forced to perform surgical removal of the mass with a concomitant reconstruction of the involved right heart structures, only 48 h after presentation. The postoperative course was uneventful, and the patient was discharged from the intensive care unit 2 days later. Radical surgical resection with reconstruction of the resected heart structures was the only possible salvage option for giant angiosarcoma, which led to hemodynamic instability. Followed by chemotherapy, this radical approach may prolong survival.
“…Primary cardiac angiosarcoma regularly has a very poor prognosis 11 . The key to achieving better long‐term outcomes when treating primary cardiac sarcomas is complete surgical resection 12 . The rarity of this tumour makes it difficult to establish standardised treatments, and early diagnosis is extremely important when choosing treatment and improving prognosis.dccd…”
This article describes the cytological morphology of angiosarcoma in a pleural effusion with immunocytochemistry applied to smears to help in the diagnosis of the case.
“…Though grafting of the RCA happened only in one of the two cases, both patients had a good right ventricular function postoperatively. [8,9] Although initial successful, the first patient died of metastasis 10 months after the surgery. The second patient survived 12 months without metastasis.…”
Cardiac angiosarcomas are rare malignant tumors, predominantly affecting the right heart with poor survival outcomes. The current mainstay of treatment consists of surgery with or without chemotherapy, but often yields limited results with local relapse or metastatic recurrence. This case report describes 2 patients with primary angiosarcoma located in the right atrium. One patient received neo-adjuvant and adjuvant chemotherapy; both were scheduled for surgical resection. The course of disease is described followed by a comprehensive review of the literature.
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