Complete blood count at the ED: preanalytic variables for hemoglobin and leukocytes

Establishment of reference intervals for complete blood count parameters during normal pregnancy in Beijing

“…Complete blood count (CBC) has evolved into the typical test panel today, including assessment of WBCs, RBCs, and platelets . Although CBC has been found to be a poor indicator for screening the undetected disease in the asymptomatic members of the general population, it provides such valuable information about a patient's or pregnant woman's physiologic status . During pregnancy, a lot of physiologic changes occur to accommodate the demands of the developing fetus, which affects the hematologic parameters directly or indirectly.…”

“…1 Although CBC has been found to be a poor indicator for screening the undetected disease in the asymptomatic members of the general population, it provides such valuable information about a patient's or pregnant woman's physiologic status. [2][3][4] During pregnancy, a lot of physiologic changes occur to accommodate the demands of the developing fetus, which affects the hematologic parameters directly or indirectly. These hematologic changes are considered to be the risk factors affecting maternal and pregnancy outcome.…”

Hemoglobin During and Following a 4-Week Commercial Saturation Dive to 200 m

“…They performed physically demanding work throughout the bottom phase, and significant fluid loss would be expected to weaken the divers physical work capacity (Saltin, 1964; Craig and Cummings, 1966); therefore, dehydration was unlikely to be a major issue. But it should be noted that reduction in plasma volume after saturation diving has been reported (Deb et al, 2017), indicating that we cannot rule out dehydration that might skew the Hb towards higher values (Carraro et al, 2015).…”

Complete blood cell count parameters and seborrheic dermatitis: Preanalytical and analytical considerations

“…Although the white blood cell count (WBC) and its derivatives, such the ANC and ALC, have been less widely studied, clinicians should be aware that preanalytical factors such as fasting conditions, position during phlebotomy, and physiologic stress may modify the results. 7 In addition, the normal circadian rhythm of the WBC may result in different results depending on the time of day the phlebotomy is performed. 7 For these reasons, we would caution the readers of The Journal of Cosmetic Dermatology to take these preanalytical and analytical phase issues into consideration before implementing the findings of Tosun et al in their practices.…”

“…7 In addition, the normal circadian rhythm of the WBC may result in different results depending on the time of day the phlebotomy is performed. 7 For these reasons, we would caution the readers of The Journal of Cosmetic Dermatology to take these preanalytical and analytical phase issues into consideration before implementing the findings of Tosun et al in their practices. Moreover, researchers should also be cognizant of these potential causes of bias in their data, and structure their data collection practices to minimize the effects of these variables.…”