Comparison of Urethral Reaction to Full Silicone, Hydrogen-coated and Siliconised Latex Catheters

Abstract

Indwelling urinary catheter may induce an inflammatory reaction or even stricture of the urethra. Catheter encrustation and urinary infection are other disadvantages associated with long-term catheterisation. In the present study, 77 male patients were catheterised randomly as part of their normal treatment with 1 of 3 different types of catheter: 22 siliconised latex, 28 hydrogel-coated latex and 27 full silicone catheters. The mean duration of catheterisation was 2.2 days. The urethral inflammatory reaction was assessed from cytological urethral swab specimens. Catheter encrustation was studied using scanning electron microscopic (SEM) analysis. The full silicone catheters induced the mildest degree of inflammation in the urethra, the percentage mean of inflammatory cells in smears being 20%. In both latex catheter groups the value was 36%. Neither the age of the patients nor the duration of catheterisation had any effect on the inflammatory reaction, which was more marked in patients with haemodynamic abnormalities. The hydrogel coating effectively prevented encrustation, while siliconised latex catheters were the least resistant to encrustation. The inflammatory reaction was variable in all patients. The use of urethral catheters should be restricted and suprapubic tubes should be used instead, particularly in patients with shock-like circulatory changes. By developing the biocompatibility and physical properties of urinary catheters, more compatible devices may be manufactured.

An in vitro comparison of urease‐induced encrustation of JJ stents in human urine

“…Therefore, hydrophilic stents reduce mechanical irritation and cell adhesion at the surrounding tissue A hydrogel is defined as a wettable polymeric biomaterial able to swell in water and to retain a significant fraction interface [1]. However, in contact with urine, hydrophilic internal stents are exposed to the risk of accumulating other four sample solutions.…”

“…The crystals formed on the comparative risk of encrustation among different stents and materials [1][2][3][4][5][6][7]. We report the results of a comparasurface of the segment were dissolved in 1.5 mL of 1% hydrochloric acid, the calcium and magnesium concentive study of in vitro encrustation of different types of current stents in human urine.…”

Types of urethral catheters for management of short-term voiding problems in hospitalized adults: a short version Cochrane Review

“…Twenty-two of the included studies were parallel group randomized controlled trials 13,[15][16][17][18][19][21][22][23][24][25][26][27][28][29][30][31][32][33][34] and one was a cluster-randomized cross-over trial 35 comparing two or three types of indwelling urinary catheters. The 22 parallel group randomized controlled trials included 5,236 hospitalized adults (mean n=208, range n=27-1,309).…”

“…Two other trials involved men only, one involved men postcardiac surgery 27 and the other included men with a variety of medical and surgical diagnoses 31 .…”

Urethral cytology in spinal cord injury patients performing intermittent catheterisation

“…Catheter induced inflammatory re sponse has been studied by Talja et al in 1990. 6 The urethral inflammatory reaction was assessed from cytological urethral swab specimens. These authors made an interest ing observation that neither the age of the patients nor the duration of catheterisation had any effect on the inflammatory re action.…”