Comparison of Two Spectral Domain Optical Coherence Tomography Devices for Angle-Closure Assessment

Quek, Desmond; Narayanaswamy, Arun; Tun, Tin A.; Htoon, Hla M; Baskaran, Mani; Perera, Shamira A.; Aung, Tin

doi:10.1167/iovs.12-10132

Cited by 41 publications

(50 citation statements)

References 16 publications

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“…Although our results were comparable to some of the best results from prior studies, 24,25 it should be noted that our metrics were SL-based rather than scleral spur-based. SL has been shown to be easier seen than the Scleral spur on SD-OCT, 22,26,27 being identified in 95% of ACA scans, 17 meaning it may represent a better anatomic landmark for assessing ACA. Having said this, although the measurement could be obtained reproducibly, it is ultimately based on our current interpretation of findings on SD-OCT images.…”

Section: Discussionmentioning

confidence: 99%

Reproducibility of Anterior Segment Angle Metrics Measurements Derived From Cirrus Spectral Domain Optical Coherence Tomography

Pan¹,

Marion²,

Maram³

et al. 2015

Journal of Glaucoma

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Section: Discussionmentioning

confidence: 99%

Reproducibility of Anterior Segment Angle Metrics Measurements Derived From Cirrus Spectral Domain Optical Coherence Tomography

Pan¹,

Marion²,

Maram³

et al. 2015

Journal of Glaucoma

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“…Prior studies have shown moderate or worse agreements between ASOCT and gonioscopy [6–8, 11, 12, 20]. However, a big limitation of those studies has been the ability to image the superior angle, which is the narrowest quadrant and typically used clinically (by gonioscopy) to determine whether a patient has open or narrow angles.…”

Section: Discussionmentioning

confidence: 99%

“…When indicated, most published studies compared superior quadrant gonioscopy with nasal/temporal meridian ASOCT images, which cannot be assumed to be equivalent, especially in eyes with PAC [8, 10, 11]. A few studies have compared gonioscopy to superior/inferior angles with visible scleral spur but have excluded 20–95% of imaged eyes [6, 7, 9, 12, 20]. …”

Section: Discussionmentioning

confidence: 99%

“…While there have been several published studies comparing angle classification using ASOCT to clinical gonioscopy [6–12], the agreements are widely variable, in large part due to the image quality and difficulty imaging the superior angle. The CASIA SS-1000 ASOCT (Tomey Corporation, Nagoya, Japan) uses Fourier domain (FD) swept source technology to provide high-resolution images (10 μ m axially and 30 μ m transversally for 2D images) for both horizontal and vertical meridians in 1.2 seconds.…”

Section: Introductionmentioning

confidence: 99%

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Agreement between Gonioscopic Examination and Swept Source Fourier Domain Anterior Segment Optical Coherence Tomography Imaging

Rigi

Bell

Lee

et al. 2016

Journal of Ophthalmology

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Purpose. To evaluate interobserver, intervisit, and interinstrument agreements for gonioscopy and Fourier domain anterior segment optical coherence tomography (FD ASOCT) for classifying open and narrow angle eyes. Methods. Eighty-six eyes with open or narrow anterior chamber angles were included. The superior angle was classified open or narrow by 2 of 5 glaucoma specialists using gonioscopy and imaged by FD ASOCT in the dark. The superior angle of each FD ASOCT image was graded as open or narrow by 2 masked readers. The same procedures were repeated within 6 months. Kappas for interobserver and intervisit agreements for each instrument and interinstrument agreements were calculated. Results. The mean age was 50.9 (±18.4) years. Interobserver agreements were moderate to good for both gonioscopy (0.57 and 0.69) and FD ASOCT (0.58 and 0.75). Intervisit agreements were moderate to excellent for both gonioscopy (0.53 to 0.86) and FD ASOCT (0.57 and 0.85). Interinstrument agreements were fair to good (0.34 to 0.63), with FD ASOCT classifying more angles as narrow than gonioscopy. Conclusions. Both gonioscopy and FD ASOCT examiners were internally consistent with similar interobserver and intervisit agreements for angle classification. Agreement between instruments was fair to good, with FD ASOCT classifying more angles as narrow than gonioscopy.

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“…Currently, OCT devices are being widely used for imaging in several biomedical fields (cardiology, urology, respiratory medicine, dermatology and developmental biology) as well as for anterior and posterior ocular segment imaging. 12,13,14,15 To this extent, several studies have reported on the practical use of OCT devices for ocular diseases associated with the retina, 15,16 cornea, 17,18 anterior chamber angle 19,20 as well as glaucoma. 21,22 Moreover, studies have also reported that OCT devices are reliable for repeated measurements of RNFL thickness in individuals with keratoconus 23,24 as well as individuals with normal corneas.…”

Section: Introductionmentioning

confidence: 99%

Retinal nerve fibre layer and ganglion cell complex thickness in patients with keratoconus

Cuppusamy

Makhanya

Methula

et al. 2018

Afr. vis. eye health

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Background: Keratoconus, a corneal ectasia, is associated with corneal thinning and altered optical media. Consequently, assessment of the visual field, optic nerve head and intraocular pressure measurements may be challenging in patients with keratoconus. Few studies have investigated posterior segment variables including the retinal nerve fibre layer (RNFL) and ganglion cell complex (GCC) thickness in patients with keratoconus.Aim: To investigate RNFL and GCC thickness in patients with keratoconus.Methods: A comparative quantitative research design was used. The sample consisted of 56 participants (28 with mild, moderate or severe keratoconus, and 28 controls) who accessed the optometry clinic at the University of KwaZulu-Natal. There was an equal distribution of male (n = 14) and female (n = 14) participants in the keratoconus and control groups. Most participants were black (n = 34) or Indian (n = 18). Corneal power and refractive error were assessed with the Oculus Keratograph and subjective refraction respectively. The iVue-100 optical coherence topography device was used to measure RNFL and GCC thickness. Data were analysed by descriptive and inferential statistics.Results: The mean global RNFL thickness was slightly higher in the control group than the keratoconus group for the right (106 µm vs. 99 µm) and left (103 µm vs. 98 µm) eyes but these differences were not significant (p ≥ 0.057). For all RNFL quadrants, slightly lower mean RNFL measurements were found in the keratoconus group. The mean GCC thicknesses were marginally higher (3 µm – 6 µm) in the control group.Conclusion: The RNFL and GCC thickness differences between patients with keratoconus and controls are not clinically significant. Therefore, abnormally reduced RNFL and GCC thickness measurements in patients with keratoconus warrant further investigation for other pathologies specifically glaucoma.

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Comparison of Two Spectral Domain Optical Coherence Tomography Devices for Angle-Closure Assessment

Abstract: It was more difficult to determine angle closure status with iVue compared with Cirrus SD-OCT. There was fair agreement between both devices with gonioscopy for identifying angle closure.

Cited by 41 publications

References 16 publications

Reproducibility of Anterior Segment Angle Metrics Measurements Derived From Cirrus Spectral Domain Optical Coherence Tomography

Reproducibility of Anterior Segment Angle Metrics Measurements Derived From Cirrus Spectral Domain Optical Coherence Tomography

Agreement between Gonioscopic Examination and Swept Source Fourier Domain Anterior Segment Optical Coherence Tomography Imaging

Retinal nerve fibre layer and ganglion cell complex thickness in patients with keratoconus

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