Abstract:A randomized controlled study was performed in 34 patients with venous leg ulcers. No difference was found in the healing rate between a new hydrocolloid dressing plus compression, and a double layer bandage, consisting of an inner paste bandage (i.e. a stocking impregnated with zinc oxide paste) and an outer elastic bandage. The parameters chosen for objective evaluation were stereophotogrammetric measurement of ulcer area and volume, and bacterial counts.
“…In two trials, the number of participants was small (n ¼ 27 and 34) and showed no difference between treatment groups. 279,294,295 However, a large RCT with 245 patients demonstrated improved healing at 24 weeks (67% vs 49%; P ¼ .009) in the multilayer (4LB) bandage group compared with the single-layer group. 296 In addition, 4LB were associated with faster wound closure (78 vs 168 days; P ¼ .001) compared with the single-layer group.…”
“…In two trials, the number of participants was small (n ¼ 27 and 34) and showed no difference between treatment groups. 279,294,295 However, a large RCT with 245 patients demonstrated improved healing at 24 weeks (67% vs 49%; P ¼ .009) in the multilayer (4LB) bandage group compared with the single-layer group. 296 In addition, 4LB were associated with faster wound closure (78 vs 168 days; P ¼ .001) compared with the single-layer group.…”
“…Four studies have been performed comparing occlusive dressings plus compression versus compression alone in venous ulcer treatment. None of the studies demonstrated any treatment‐dependent difference in the number of patients who healed by the end of 12 weeks 32–35 . In one study, however, there was an increased rate of venous ulcer healing over the first 4 weeks in patients treated with occlusive dressings plus compression 35 …”
Section: Occlusive Dressings For Chronic Woundsmentioning
Good wound care and compression therapy will heal the majority of small venous ulcers of short duration. For ulcers that are slow to heal, other approaches such as venous surgery and grafting with conventional or bioengineered skin substitutes should be considered.
“…16,17 Future research is needed to understand which patients benefit most from each modality and what levels of elasticity and extensibility are ideal for which conditions, eg, ambulatory versus sedentary patients. However 2 RCTs show that for some patients or usage parameters, healing outcomes can be similar.…”
Section: Question 2: Which Types Of Compression Derive the Best Evidementioning
confidence: 99%
“…17,18 Further research is needed to determine whether there are interactive effects of primary wound dressing and compression modality. Two small RCTs, one outside an earlier meta-analysis drawing this conclusion, found no significant difference in healing of multilayer versus single-layer compression bandages when the primary wound dressing beneath the single layer was a hydrocolloid dressing.…”
Section: Question 2: Which Types Of Compression Derive the Best Evidementioning
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