Comparison of two cotside methods for the detection of hypoglycaemia among neonates in Nepal

Ellis, Matthew; Manandhar, D.; Manandhar, Nilu; Land, JM; Patel, Nishant; Costello, Amdl

doi:10.1016/s0378-3782(97)90582-x

Cited by 5 publications

(9 citation statements)

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“…They concluded that Hemocue measurements were not sufficiently accurate to replace blood glucose measurements performed in a laboratory, but may be useful in detection of life-threatening hypoglycaemia. A more recent study by Ellis et al 14 found that Hemocue analysers gave neonatal glucose results I· 7 rnmol/L higher than a laboratory glucose oxidase system. They achieved comparable glucose results with the laboratory only by subtracting 2 mmol/L from every glucose result obtained on the Hemocue, and felt unable to recommend Hemocue analysers in neonatal bedside glucose monitoring.…”

Section: Discussionmentioning

confidence: 92%

The Use of a Hemocue Blood Glucose Analyser in a Neonatal Unit

1997

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SUMMARY. Near patient testing for glucose is now a widely accepted procedure in hospital wards and clinics. However, in a neonatal ward where the detection of hypoglycaemia rather than hyperglycaemia is of paramount importance, it is more difficult to find a suitable glucose monitoring instrument. We compared two Hemocue blood glucose analysers (Hemocue Ltd) in our special care baby unit (SCBU) with the laboratory procedures and found that the Hemocue may overestimate the glucose by as much as 2·5 mmol/L, In addition, Hemocue analysers are costly to run. We feel these analysers may be more useful in a general ward rather than in a SCBU. Additional key phrases: near-patient testing; point of care testing; paediatrics; hypoglycaemiaNear-patient testing of blood glucose by ward staff can be difficult, involving in-house training, stringent adherence to protocols, quality assurance and maintenance of instruments.

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Section: Discussionmentioning

confidence: 92%

The Use of a Hemocue Blood Glucose Analyser in a Neonatal Unit

1997

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“…This is in agreement with the ndings of other studies (4, 10). Ellis et al, however, found that the BM Strip test underestimated blood glucose in neonates (11). This was probably due to the immediate proces-sing of the blood samples, which involved storing them at ¡20°C.…”

Section: Discussionmentioning

confidence: 99%

Comparison of two strip test methods of whole blood glucose measurement in the neonatal period

Papp¹

2001

Acta Paediatrica

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“…Various studies have evaluated their accuracies. [9][10][11][12][13][14][15][16] The Reflolux S glucometer was the one commonly used in our neonatal unit, although, in our experience, it usually underestimated the true plasma concentration. New portable glucometers have recently been introduced on to the market.…”

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confidence: 99%

Evaluation of "point of care" devices in the measurement of low blood glucose in neonatal practice

Yeung²,

Young³

2004

Archives of Disease in Childhood - Fetal and Neonatal Edition

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Background: Low blood glucose in newborns is difficult to detect clinically. Hence a reliable ''point of care'' device (glucometer) for early detection and treatment of low glucose is needed. Objective: To evaluate the performance of five readily available glucometers for the detection of low blood glucose in newborn infants. Method: Glucostix measurements were taken for newborns with risk factors using a Reflolux S (Boehringer) glucometer. If the initial reading was low (, 2.6 mmol/l), further measurements were taken with two other glucometers (phase I, Advantage and Glucotrend (Roche); phase II, Elite XL (Bayer) and Precision (Abbott)), and plasma glucose was measured in the laboratory (Aeroset; Abbott). Results: Over 10 months, 101 specimens were collected from 71 newborns (57 in phase I; 44 in phase II). The Advantage glucometer usually overestimated blood glucose with a mean difference of 1.07 mmol/l (p , 0.01) at all low glucose ranges. The Glucotrend, Precision, and Elite XL glucometers performed better; the mean differences were not significantly different from the laboratory measured value (0.17 mmol/l (p = 0.37); 20.12 mmol/l (p = 0.13), and 0.24 mmol/l (p = 0.13) respectively). For detection of glucose concentrations , 2.6 mmol/l, the Precision glucometer had the highest sensitivity (96.4%) and negative predictive value (90%). For lower glucose concentrations (, 2.0 mmol/l), the Glucotrend glucometer performed even better (sensitivity 92.3%, negative predictive value 96.3%). Conclusion: Point of care devices should have good precision in the low glucose concentration range, sensitivity, and accuracy for early detection of neonatal hypoglycaemia. None of the five glucometers was satisfactory as the sole measuring device. The Glucotrend and Precision glucometers have the greatest sensitivity and negative predictive value. However, confirmation with laboratory measurements of plasma glucose and clinical assessment are still of the utmost importance.

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Comparison of two cotside methods for the detection of hypoglycaemia among neonates in Nepal

Cited by 5 publications

References 0 publications

The Use of a Hemocue Blood Glucose Analyser in a Neonatal Unit

The Use of a Hemocue Blood Glucose Analyser in a Neonatal Unit

Comparison of two strip test methods of whole blood glucose measurement in the neonatal period

Evaluation of "point of care" devices in the measurement of low blood glucose in neonatal practice

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