Comparison of two strip test methods of whole blood glucose measurement in the neonatal period

Papp, N Sharief M

doi:10.1080/080352501316978138

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…This suggests that when comparing preterm infants or low birth-weight infants to adults, the measurement values of portable glucometers have a lower level of correlation with the measurement results of laboratory equipment; the difference is even larger under conditions of hypoglycemia. These study results are similar to the results obtained in several previous studies 3 5 11) .…”

Section: Discussionsupporting

confidence: 93%

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Evaluation of three glucometers for whole blood glucose measurements at the point of care in preterm or low-birth-weight infants

et al. 2015

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PurposeWe evaluated three blood glucose self-monitoring for measuring whole blood glucose levels in preterm and low-birth-weight infants.MethodsBetween December 1, 2012 and March 31, 2013, 230 blood samples were collected from 50 newborns, who weighed, ≤2,300 g or were ≤36 weeks old, in the the neonatal intensive care unit of Eulji University Hospital. Three blood glucose self-monitoring (A: Precision Pcx, Abbott; B: One-Touch Verio, Johnson & Johnson; C: LifeScan SureStep Flexx, Johnson & Johnson) were used for the blood glucose measurements. The results were compared to those obtained using laboratory equipment (D: Advia chemical analyzer, Siemens Healthcare Diagnostics Inc.).ResultsThe correlation coefficients between laboratory equipment and the three blood glucose self-monitoring (A, B, and C) were found to be 0.888, 0.884, and 0.900, respectively. For glucose levels≤60 mg/dL, the correlation coefficients were 0.674, 0.687, and 0.679, respectively. For glucose levels>60 mg/dL, the correlation coefficients were 0.822, 0.819, and 0.839, respectively. All correlation coefficients were statistically significant. And the values from the blood glucose self-monitoring were not significantly different from the value of the laboratory equipment , after correcting for each device's average value (P>0.05). When using laboratory equipment (blood glucose ≤60 mg/dL), each device had a sensitivity of 0.458, 0.604, and 0.688 and a specificity of 0.995, 0.989, and 0.989, respectively.ConclusionSignificant difference is not found between three blood glucose self-monitoring and laboratory equipment. But correlation between the measured values from blood glucose self-monitoring and laboratory equipment is lower in preterm or low-birth-weight infants than adults.

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Section: Discussionsupporting

confidence: 93%

“…Hypoglycemia is one of the most common metabolic disorders in infants. Persistent hypoglycemia can cause abnormalities in neuronal development 1 2 3 4) . The clinical signs of hypoglycemia in the neonate are not specific to alterations in glucose concentration.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of three glucometers for whole blood glucose measurements at the point of care in preterm or low-birth-weight infants

et al. 2015

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Metrological Support of Individual Blood Glucose Meters in Telemedicine

Glukhov¹,

Krutikov²,

Иванов

et al. 2020

Meas Tech

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Evaluation of "point of care" devices in the measurement of low blood glucose in neonatal practice

Yeung²,

Young³

2004

Archives of Disease in Childhood - Fetal and Neonatal Edition

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Background: Low blood glucose in newborns is difficult to detect clinically. Hence a reliable ''point of care'' device (glucometer) for early detection and treatment of low glucose is needed. Objective: To evaluate the performance of five readily available glucometers for the detection of low blood glucose in newborn infants. Method: Glucostix measurements were taken for newborns with risk factors using a Reflolux S (Boehringer) glucometer. If the initial reading was low (, 2.6 mmol/l), further measurements were taken with two other glucometers (phase I, Advantage and Glucotrend (Roche); phase II, Elite XL (Bayer) and Precision (Abbott)), and plasma glucose was measured in the laboratory (Aeroset; Abbott). Results: Over 10 months, 101 specimens were collected from 71 newborns (57 in phase I; 44 in phase II). The Advantage glucometer usually overestimated blood glucose with a mean difference of 1.07 mmol/l (p , 0.01) at all low glucose ranges. The Glucotrend, Precision, and Elite XL glucometers performed better; the mean differences were not significantly different from the laboratory measured value (0.17 mmol/l (p = 0.37); 20.12 mmol/l (p = 0.13), and 0.24 mmol/l (p = 0.13) respectively). For detection of glucose concentrations , 2.6 mmol/l, the Precision glucometer had the highest sensitivity (96.4%) and negative predictive value (90%). For lower glucose concentrations (, 2.0 mmol/l), the Glucotrend glucometer performed even better (sensitivity 92.3%, negative predictive value 96.3%). Conclusion: Point of care devices should have good precision in the low glucose concentration range, sensitivity, and accuracy for early detection of neonatal hypoglycaemia. None of the five glucometers was satisfactory as the sole measuring device. The Glucotrend and Precision glucometers have the greatest sensitivity and negative predictive value. However, confirmation with laboratory measurements of plasma glucose and clinical assessment are still of the utmost importance.

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Comparison of two strip test methods of whole blood glucose measurement in the neonatal period

Abstract: The new Advantage glucose meter does not offer any advantage over the BM Strip test. Owing to the wide limits of agreement of both methods compared with plasma glucose, their clinical value is limited in the neonatal period.

Cited by 4 publications

References 8 publications

Evaluation of three glucometers for whole blood glucose measurements at the point of care in preterm or low-birth-weight infants

Evaluation of three glucometers for whole blood glucose measurements at the point of care in preterm or low-birth-weight infants

Metrological Support of Individual Blood Glucose Meters in Telemedicine

Evaluation of "point of care" devices in the measurement of low blood glucose in neonatal practice

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