Comparison of Topical Lidocaine Spray With Placebo for Pain Relief in Colposcopic Procedures

Öz, Murat; Korkmaz, Elmas; Cetinkaya, Nilufer; Baş, Sevda; Özdal, Bülent; Meydanl, Mehmet Mutlu; Güngör, Tayfun

doi:10.1097/lgt.0000000000000099

Cited by 19 publications

(19 citation statements)

References 7 publications

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“…However, all tissues could still be evaluated by pathologic results. The VAS pain score associated in each procedure was 3.4 in both groups which was similar to another study that reported pain scores during the punch biopsy forceps procedure as 2.31±1.60 [ 12 ].…”

Section: Discussionsupporting

confidence: 86%

“…However, a disadvantage of punch biopsy forceps is the tissue may slide which results in tissue fragments being sent to the pathologist. In general, no topical anesthesia is used during a CDB because ibuprofen or topical lidocaine were not shown to reduce pain [ 11 12 ]. Pain scores during punch biopsy forceps were 2.31±1.60 [ 12 ] but currently there is no study to compare pain scores of each biopsy procedure.…”

Section: Introductionmentioning

confidence: 99%

“…In general, no topical anesthesia is used during a CDB because ibuprofen or topical lidocaine were not shown to reduce pain [ 11 12 ]. Pain scores during punch biopsy forceps were 2.31±1.60 [ 12 ] but currently there is no study to compare pain scores of each biopsy procedure. A study to compare the quality of tissue from punch biopsy forceps with round loop electrodes in CDB has not been reported.…”

Section: Introductionmentioning

confidence: 99%

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Quality of tissue from punch biopsy forceps vs. round loop electrode in colposcopically directed biopsy: a randomized controlled trial

2018

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ObjectiveTo compare the quality of tissue from punch biopsy forceps (PB group) with round loop electrode (LE group) in colposcopically directed biopsy along with the evaluation of pain associated with each procedure.MethodsPatients with abnormal cervical cytologic results and abnormal colposcopic findings were enrolled into a randomized trial into either a PB group or LE group. The quality of tissue was evaluated in regards to the size of tissue, site of tissue, and tissue damage. Each quality had 1 to 3 points and the sum of each quality contributed to the total tissue score that ranged from 3 to 9. Pain associated with each procedure was assessed by a visual analog scale (VAS). This was a clinical trial study and was registered at www.clinicaltrials.in.th (Identifier: TCTR20160404001).ResultsNinety-six women who met all eligibility requirements were enrolled in the study. Forty-eight patients were randomly assigned to the PB group and 48 patients were randomized into the LE group. The characteristics of the patients were similar between the 2 groups with the exception of the median age. The median total tissue score was 8 points in the LE group which was more than the median of 7 points in the PB group with a statistically significant difference (p=0.014). However, the median VAS pain score in both groups was 3.4 (p=0.82).ConclusionThe quality of cervical tissues obtained from biopsy with a round loop electrode was better than the punch biopsy forceps with no difference in the level of pain.

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Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Quality of tissue from punch biopsy forceps vs. round loop electrode in colposcopically directed biopsy: a randomized controlled trial

2018

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“…Öz et al compared five puffs (50 mg) of lidocaine spray with placebo during cervical biopsies and endocervical curettage. Pain scores after procedures were comparable in both study arms.…”

Section: Discussionmentioning

confidence: 99%

Effect of lidocaine spray during colposcopy‐directed cervical biopsy: A randomized controlled trial

Wongluecha

Tantipalakorn

Charoenkwan

et al. 2017

J of Obstet and Gynaecol

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“…[ 3 , 4 ] However, topical anesthetic sprays and gels were ineffective in providing pain relief. [ 5 – 7 ]…”

Section: Introductionmentioning

confidence: 99%

Factors affecting pain during outpatient clinic based surgical procedures in gynecologic oncology

Kim¹,

Lee

Park

et al. 2018

Medicine

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Colposcopy-directed punch biopsy (punch biopsy) and endocervical curettage (ECC) are accompanied by considerable pain. However, many physicians perform these procedures without adequate pain management. Therefore, identification of factors affecting pain experienced during the procedures may encourage physician effort in selective pain management. This study investigated factors affecting the severity of pain experienced during punch biopsy and ECC in an outpatient clinic of gynecologic oncology department.In this retrospective, exploratory study, a total of 101 Korean patients with abnormal cervical cytology underwent punch biopsy and ECC under a paracervical block performed for pain relief. Residents under training performed these procedures and recorded patient-reporting maximum Numeric Rating Scale (NRS) scores experienced during the procedures. Residents were classified into four outpatient clinic training groups (1st–4th); the group designators correspond to the resident's experience in performing these procedures. A linear mixed model adjusted for physician factors such as either residents or outpatient clinic training groups was used to analyze the association between each variable and maximum NRS score.Among the outpatient clinic training groups, maximum NRS scores significantly decreased in the 4th group, compared with those in the 1st group although those were not different among groups when adjusted for residents. Some of cervical cytology findings and discrepancies between the severity of cervical cytology results and those of punch biopsy or ECC showed significant associations with maximum NRS scores. However, when adjusted for either residents or outpatient clinic training groups, maximum NRS scores were not different by age, body mass index, presence of menopause, cervical cytology findings, discrepancies between the severity of cervical cytology results and those of punch biopsy or ECC, and tissue volume.There are no significant factors affecting the severity of pain experienced during punch biopsy and ECC.

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Comparison of Topical Lidocaine Spray With Placebo for Pain Relief in Colposcopic Procedures

Abstract: In our population, there is no evidence to recommend the use of routine locally sprayed lidocaine anesthesia before cervical punch biopsy or ECC.

Cited by 19 publications

References 7 publications

Quality of tissue from punch biopsy forceps vs. round loop electrode in colposcopically directed biopsy: a randomized controlled trial

Quality of tissue from punch biopsy forceps vs. round loop electrode in colposcopically directed biopsy: a randomized controlled trial

Effect of lidocaine spray during colposcopy‐directed cervical biopsy: A randomized controlled trial

Factors affecting pain during outpatient clinic based surgical procedures in gynecologic oncology

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