Comparison of the thermal stability of ciprofloxacin and its compounds

The crystal habit of ciprofloxacin hydrochloride monohydrate crystal

“…the same de-hydrate apex temperature (17072 1C), the same melting apex temperature (32672 1C) and the same decomposition apex temperature (35072 1C). These results of DSC for CPFX are well in agreement with that reported in literature [9].…”

Radiation cross-linked carboxymethyl sago pulp hydrogels loaded with ciprofloxacin: Influence of irradiation on gel fraction, entrapped drug and in vitro release

“…The small peak at 156 1C corresponds to the complete loss of water molecules as the drug possessed hygroscopic property (Yong et al, 2005). The dominant peak at 322 1C corresponds to the melting point of the crystalline ciprofloxacin HCl (Turel and Bukovec, 1996).…”

Preparation and Thermal Decomposition Kinetics of Polyoxometalate of Ciprofloxacin with 12-Tungstosilicic Acid

“…7 with β＝10 K/min and Eqs. (4)- (6). Therefore, it can be concluded that the decomposition in the second step was controlled by phase boundary reaction (contracting sphere) and the kinetic equation of this process was dα/dt＝Ae T 2 A1.5 Assumed random nucleation and its subsequent growth, n＝2/3 (1-α)ln(1-α)＋α 10 D3 Three-dimensional diffusion, spherical symmetry, Jander equation, n＝2…”

“…In the last few years, the coordination chemistry of these pyridone carboxylic acids with metal ions of biological and pharmaceutical importance is of considerable interest. Wallis 4 and López-Gresa 5 reported synthesis, crystal structure and bacterial activity of some metal complexes of ciprofloxacin, and Turel 6 and Zupančič 7 reported the thermal stability of ciprofloxacin complexes with some metal ions. However, studies on preparation and thermal properties of the complexes of ciprofloxacin with heteropoly acids are scarce.…”