Comparison of the effects of Matricaria chamomila (Chamomile) extract and mefenamic acid on the intensity of premenstrual syndrome

Sharifi, Farid; Simbar, Masoumeh; Mojab, Faraz; Majd, Hamid Alavi

doi:10.1016/j.ctcp.2013.09.002

Cited by 42 publications

(26 citation statements)

References 7 publications

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“…It was also in line with the results of the study by Modarres et al aimed at the effect of chamomile and mefenamic acid capsules in Tehran [22], indicating that after the end of the first 3 days of menstruation, the severity of pain in the chamomile group decreased significantly. However, the present study showed contradictory results with the study by Sharifi et al which focused on the analgesic effects of mefenamic Acid and Chamomile on the severity of pain in the menstrual period [23]. whereby drugs were used every 8 hours on the first three days of menstruation, but after the end of the first 3 days, there was no significant difference between the two groups of chamomile capsules and mefenamic acid.…”

Section: Discussioncontrasting

confidence: 99%

Comparative Study on the Effect of Matricaria chamomile and Achillea millefolium Capsules on Primary Dysmenorrhea Intensity of Dormitory Students of Kurdistan University of Medical Sciences, 2018

Radfar

Shahoie

Noori

et al. 2019

JPRI

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Background: Menstrual pain is the most common pain and one of the main causes of referral to a doctor among young women. The aim of this study was to compare the effectiveness of Achillea millefolium (Yarrow) and Matricaria chamomile plants to treat menstrual pain. Methods: This double-blind randomized controlled trial study was performed on 50 female students of Kurdistan Medical Sciences residing in dormitory in 2018. Individuals were randomly divided into two groups of chmomile and yarrow using sealed envelopes. Twenty for people received 250 mg chamomile capsules every 8 hours and 26 people received 150 mg hydroalcoholic capsules of yarrow every 8 hours during the first three days of menstruation in two menstrual cycles. The data collection tool was a questionnaire and the severity of pain was assessed using visual analogue scale for the pain (VAS). Results: There was no significant difference between the two groups in terms of pain severity and duration of pain before taking the drug (p > 0.05). The average pain severity in the first menstrual cycle in the two groups decreased significantly (p< 0.05), which was more noticeable in the yarrow group. However, the average pain severity in the yarrow capsule group was lower than that of the chamomile capsule group, but this difference was not statistically significant (p > 0.05). Conclusion: Both capsules of yarrow and chamomile reduce the severity of pain, but the yarrow capsule, with its long-lasting sedative effect, proved more helpful to reduce the severity of menstrual pain and could be effective in solving one of the issues among women.

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Section: Discussioncontrasting

confidence: 99%

Comparative Study on the Effect of Matricaria chamomile and Achillea millefolium Capsules on Primary Dysmenorrhea Intensity of Dormitory Students of Kurdistan University of Medical Sciences, 2018

Radfar

Shahoie

Noori

et al. 2019

JPRI

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“…In clinic practices, chemical drugs such as mefenamic acid and fluoxetine are effective in reduction of PMS symptoms [11,[18][19][20][21]. Since, chemical drugs have side effects and based on this reason except in severe cases, chemical drugs are not recommended for treating PMS.…”

Section: Discussionmentioning

confidence: 99%

Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial

Khayat

Fanaei

Kheirkhah

et al. 2015

Complementary Therapies in Medicine

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“…The results showed no significant difference between the two groups so the chamomile acts similarly to mefenamic acid in the healing of physical symptoms (p > 0.05) [54]. …”

Section: Resultsmentioning

confidence: 99%

Effective Medicinal Plants in the Treatment of the Cyclic Mastalgia (Breast Pain): A Review

et al. 2019

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Comparison of the effects of Matricaria chamomila (Chamomile) extract and mefenamic acid on the intensity of premenstrual syndrome

Cited by 42 publications

References 7 publications

Comparative Study on the Effect of Matricaria chamomile and Achillea millefolium Capsules on Primary Dysmenorrhea Intensity of Dormitory Students of Kurdistan University of Medical Sciences, 2018

Comparative Study on the Effect of Matricaria chamomile and Achillea millefolium Capsules on Primary Dysmenorrhea Intensity of Dormitory Students of Kurdistan University of Medical Sciences, 2018

Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial

Effective Medicinal Plants in the Treatment of the Cyclic Mastalgia (Breast Pain): A Review

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