Comparison of the effects of on‐pump versus off‐pump coronary artery bypass surgery on serum prostate‐specific antigen levels

Parlaktaş, Bekir Süha; Naseri, Erdinç; Uluocak, Nıhat; Elalmiş, Altay Ömer; Erdemır, Fikret; Etikán, Ílker

doi:10.1111/j.1442-2042.2006.01275.x

Cited by 13 publications

(17 citation statements)

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“…Parlaktas and colleagues also observed a significant difference in PSA levels between the first and the fifth days after bypass surgery. One can assume that the main reason for PSA elevation after the surgery is revascularization which is stronger the first days and after that subsides (17). Some researchers believe that urethral catheterization and slight trauma to the prostate can elevate serum PSA levels (18,19).…”

Section: Discussionmentioning

confidence: 99%

Association between prostate specific antigen levels and coronary artery angioplasty

et al. 2016

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Introduction: Prostate-specific antigen (PSA) is a protein, whose serum levels changes during various physiologic and pathologic situations. Recently, the relationship between PSA and cardiologic disorders has been assessed. Objectives: The purpose of this study was to assess the association of percutaneous coronary intervention (PCI) complications with PSA serum levels. Patients and Methods: In this study, 100 eligible patients undergoing PCI were included. The total PSA serum values were analyzed pre- and post-procedure. The association between PSA levels with age, gender, inflammatory (C-reactive protein [CRP] and white blood cell [WBC]), cardiogenic (troponin, CK-MB, echocardiography and angiography results), and nephrology (creatinine) properties was investigated. Results: Changes in the level of PSA pre- and post-PCI was not significant (P=0.2). However, based on the pathology, patients with acute coronary syndrome (ACS) had a significant difference in the levels of PSA compared to cases of stable ischemic heart disease (SIHD) (P=0.008). Moreover, the effect of gender on the changes in PSA level following PCI was conclusive. There was no association between the direct effect of PCI parameters or PCI complications on PSA level changes. Conclusion: The results showed that PSA levels were affected by the etiology of cardiac disorders instead of therapeutic methods like PCI.

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Section: Discussionmentioning

confidence: 99%

Association between prostate specific antigen levels and coronary artery angioplasty

et al. 2016

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“…Changes in serum PSA levels are reported in certain clinical cardiac problems such as acute myocardial infarction (AMI) , cardiac surgery, extracorporeal cardiac by-pass (Parlaktas et al, 2006), stent implantation (Ozcan et al, 2009) and cardiopulmonary resuscitation (Koller-Strametz et al, 2000). There are some case reports investigating the changes in PSA levels after AMI (Patane & Marte, 2009a;.…”

Section: Introductionmentioning

confidence: 99%

Prostate specific antigen levels after acute myocardial infarction.

Açıkgöz

Can²,

Doğan³

et al. 2011

Acta Biochim Pol

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Prostate Specific Antigen (PSA), a member of kallikrein family, is a specific serine protease of prostatic tissue. In some case reports, changes in PSA levels after acute myocardial infarction (AMI) have been reported. In this study we evaluated variations in PSA levels post-AMI. Twenty-six male patients who had PSA levels within reference limits were included in the study. The diagnosis of AMI was confirmed by clinical findings, ECG (electrocardiogram) and cardiac marker studies. Serum total PSA (tPSA) and free PSA (fPSA) levels were measured at days 0 (day of admission), 1, 2 and 3 after AMI. PSA/albumin ratio was also calculated in order to evaluate the effect of dilution. A statistical analysis of the results of all patients revealed significant decrease in tPSA levels and tPSA/Albumin ratio at day 2 when compared to days 0 and 3, which showed a similar pattern. Changes of fPSA and fPSA/ Albumin ratio according to days were not found significant. In only four patients we found increased levels of tPSA and increased fPSA levels in three of them. These patients displayed severe problems such as renal failure, cardiac failure, ventricular aneurysm and cerebral ischemia due to cardiac arrest. The lower tPSA levels on day 2 suggest that tPSA can be eliminated rapidly from the circulation on days 1 and 2, probably through the formation of complexes of tPSA with acute phase proteins.

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“…Increasing evidence suggests that PSA relates to the cardiovascular system [3]. Of note, increased PSA serum levels have been reported after prolonged cardiopulmonary resuscitation [4,5], cardiac surgery [6], extracorporeal cardiopulmonary bypass [7,8], cardiogenic shock due to acute myocardial infarction (AMI) [9], AMI [10][11][12][13][14][15][16][17][18][19] and coronary artery stenting [20]. However, also decreased PSA serum levels have been reported during AMI [2,21,22] and this latter finding has opened a new possible intriguing scenario [1,16,18,21,23].…”

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confidence: 97%

Prostate-specific antigen kallikrein and non-ST elevation myocardial infarction

Patanè¹

2011

International Journal of Cardiology

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Comparison of the effects of on‐pump versus off‐pump coronary artery bypass surgery on serum prostate‐specific antigen levels

Abstract: Coronary revascularization can cause a statistically significant rise in serum total prostate-specific antigen levels. This rise is more marked in patients undergoing conventional coronary revascularization.

Cited by 13 publications

References 20 publications

Association between prostate specific antigen levels and coronary artery angioplasty

Association between prostate specific antigen levels and coronary artery angioplasty

Prostate specific antigen levels after acute myocardial infarction.

Prostate-specific antigen kallikrein and non-ST elevation myocardial infarction

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