Comparison of the Effectiveness of Pars Plana Vitrectomy with and without Internal Limiting Membrane Peeling for Idiopathic Retinal Membrane Removal: A Meta-Analysis

Liu, Hanhan; Zuo, Shi; Ding, Chun; Dai, Xunzhang; Zhu, Xiang

doi:10.1155/2015/974568

Cited by 33 publications

(42 citation statements)

References 42 publications

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“…Visual acuity ﬁndings in our meta-analysis are likely explained by the fact that additional ILM peeling provided no improvement in functional outcomes, these findings were in consistent with the previous review,39 but contrast to a recent meta-analysis,40 which revealed that ILM peeling group had better BCVA after surgery within 12 months, but worse BCVA in the 18th month.…”

Section: Discussionsupporting

confidence: 89%

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Internal limiting membrane peeling or not: a systematic review and meta-analysis of idiopathic macular pucker surgery

et al. 2017

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Section: Discussionsupporting

confidence: 89%

“…Recently, we found a meta-analysis about this topic that was published on 26 November 2015 40. There are some disagreements between our review and this paper.…”

Section: Discussionmentioning

confidence: 71%

Internal limiting membrane peeling or not: a systematic review and meta-analysis of idiopathic macular pucker surgery

et al. 2017

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“…Recently, two meta-analyses reported results of ERM and ILM peeling compared to ERM peeling alone, coming to different results. While one meta-analysis reported BCVA to be better in the ERM and ILM peeling group within 12 months after surgery, but BCVA to be better in the ERM peeling group in the 18th month [34], the other meta-analysis reported BCVA to be better in the ERM peeling group within 12 months after surgery and BCVA to be better in the ERM and ILM peeling group after 18 months after surgery [35]. The ERM peeling group without ILM peeling showed higher reduction in central retinal thickness, but also higher ERM recurrence rates [35].…”

Section: Discussionmentioning

confidence: 99%

Intraoperative Optical Coherence Tomography-Guided Membrane Peeling for Surgery of Macular Pucker: Advantages and Limitations

et al. 2018

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Purpose: Epiretinal membranes (ERMs) are a disorder leading to progressive vision loss and metamorphopsia. The gold standard in therapy is vitrectomy with membrane peeling. The aim of this study was to assess whether the use of intraoperative optical coherence tomography (iOCT), which allows tomographic visualization of the membrane during peeling, enables peeling without staining. Methods: This prospective study included 30 eyes of 30 patients with idiopathic ERMs scheduled for surgery. Pars plana vitrectomy with iOCT was performed in all cases, whereas staining of ERMs was only performed if needed. Internal limiting membrane (ILM) peeling was performed in case of wrinkled retinal surface after peeling of ERMs. Results: In 63% (n = 19) eyes the ERM could be peeled successfully without use of staining. Nevertheless, in 89% (n = 17) of patients having had ERM peeling without dye, staining of the ILM was performed afterwards for peeling the ILM. Best corrected visual acuity improved in 80% (n = 24) and remained unchanged in 7% (n = 2) 3 months after surgery. There were no significant differences in postoperative results between patients with and without staining for ERM peeling. Conclusions: Use of iOCT helps to complete ERM peeling in a majority of cases without use of a chromovitrectomy dye, but as iOCT fails to visualize the ILM, chromovitrectomy still facilitates macular surgery in a majority of cases.

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“…The cause of its existence is not yet clear. However, it has been attributed mostly to posterior vitreous detachment (PVD) [1], which provokes glial cells (Muller) and extracellular components to accumulate and migrate on the ILM [2]. The prevalence of ERM ranges from 1.02% to 18.5% [3].…”

Section: Introductionmentioning

confidence: 99%

“…Triamcinolone, indocyanine green and triphenylmethane (brilliant blue) are dyes which can be used during the operation [2]. The rate of recurrence of ERM formation is 10%-16.3% [1]. It is usual for the ILM to be peeled because it acts like a scaffold for cells' proliferation on the macula.…”

Section: Introductionmentioning

confidence: 99%

Long Term Outcomes after Pars Plana Vitrectomy for the Treatment of Epiretinal Membranes

Mela¹

2016

AOVS

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Purpose: To report the long-term outcomes of surgical treatment of epiretinal membranes (ERM) with pars plana vitrectomy (PPV) and internal limiting membrane (ILM) peeling.Methods: This was a retrospective interventional case series of patients with symptomatic ERM. 340 eyes of 322 patients were included in the study. Mean age of the sample was 68±12 years. Preoperative and postoperative Corrected Distance Visual Acuity (CDVA), as well as Intraocular Pressure (IOP) measurements were compared, Central Macular Thickness (CMT) from Optical Coherence Tomography (OCT) was correlated with CDVA at all time intervals. Results:No intraoperative or immediate postoperative complications were observed. Mean preoperative CDVA was 0.6±0.3 logMAR. Statistically significant improvement was noted at all postoperative follow ups (P<0.002). Mean postoperative CDVA at last follow up visit was 0.2±0.2 logMAR. The rate of CDVA's improvement was 67%. IOP measurements showed a statistically significant increase at the 1st postoperative month and then approached the preoperative values, without statistical significance. Mean CMT measurements showed gradual reduction at all follow up visits, from 427±91μm to 268±40μm at the last visit (P<0.0001). The preoperative CMT was statistically significant correlated with pre-and postoperative CDVA at the 6th month, 1 year and last follow up visit (p<0.05). Statistically significant correlations were also found between 1 month postoperative CMT and 1 year postoperative CDVA (P<0.02). CDVA at the last examination was significant correlated with postoperative CMT at 1 month, 6 months (P<0.0001). After multivariate linear regression, postoperative CMT at 1st month, 6th months and 1 year was correlated with CDVA at the last follow up examination. Conclusion:PPV with ILM peel is a justifiable intervention for patients with ERMs, which may offer CDVA improvement and continuous regularization of foveal anatomy through the next years.

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Comparison of the Effectiveness of Pars Plana Vitrectomy with and without Internal Limiting Membrane Peeling for Idiopathic Retinal Membrane Removal: A Meta-Analysis

Cited by 33 publications

References 42 publications

Internal limiting membrane peeling or not: a systematic review and meta-analysis of idiopathic macular pucker surgery

Internal limiting membrane peeling or not: a systematic review and meta-analysis of idiopathic macular pucker surgery

Intraoperative Optical Coherence Tomography-Guided Membrane Peeling for Surgery of Macular Pucker: Advantages and Limitations

Long Term Outcomes after Pars Plana Vitrectomy for the Treatment of Epiretinal Membranes

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