Comparison of stability between a modular intraocular lens system and a single-piece hydrophobic acrylic intraocular lens

Abstract

Proprietary or commercial disclosures are listed after the references.

Long‐term uveal and capsular biocompatibility of a novel modular intraocular lens system

“…As errors in predicted postoperative anterior chamber depth (used as a surrogate for ELP) account for the largest percentage of incorrect IOL power calculations (SooHoo et al. ), a modular IOL system like this with superior capsular stability that also allows for intra‐operative optic power selection after direct ELP calculation could significantly reduce incorrect IOL power calculations.…”

“…The superior stability of the modular system may be due to design features including a stable haptic–base junction intended to prevent motion in the anterior–posterior plane and a base unit designed to occupy additional space in the peripheral capsular bag (SooHoo et al. ).…”

“…This finding is particularly relevant to paediatric cataract surgery as multiple IOL exchanges are often required many years after the original procedure due to unpredictable degrees of myopic shift (Kraus et al 2016). In addition to affording easier postoperative IOL exchange, the ClarVista Harmoni Ò Modular system was shown in a previous ex vivo study by SooHoo et al (2016) to be more stable in the capsular bag under changes in IOP than a standard single-piece hydrophobic acrylic IOL. This could improve IOL power selection by allowing for precise intra-operative measurement of effective lens position (ELP) after implantation of the base unit with ultrasound or optical coherence tomography with subsequent calculation of IOL power and implantation of the correct optic unit.…”

“…This could improve IOL power selection by allowing for precise intra-operative measurement of effective lens position (ELP) after implantation of the base unit with ultrasound or optical coherence tomography with subsequent calculation of IOL power and implantation of the correct optic unit. As errors in predicted postoperative anterior chamber depth (used as a surrogate for ELP) account for the largest percentage of incorrect IOL power calculations (SooHoo et al 2016), a modular IOL system like this with superior capsular stability that also allows for intra-operative optic power selection after direct ELP calculation could significantly reduce incorrect IOL power calculations. This is the first long-term in vivo study of the ClarVista HarmoniÒ Modular IOL system in the rabbit model and was conducted in accordance with FDA GLP regulations and international standards.…”

“…Additionally, in spite of the accelerated proliferation of cortical material in the rabbit model, all of the modular IOL systems were found to be stable and well centred at the conclusion of the study, while more than half of the control lenses demonstrated partial pupillary optic capture. The superior stability of the modular system may be due to design features including a stable haptic-base junction intended to prevent motion in the anterior-posterior plane and a base unit designed to occupy additional space in the peripheral capsular bag (SooHoo et al 2016).…”