Comparison of six depression rating scales in geriatric stroke patients.

Agrell, Berit; Dehlin, Ove

doi:10.1161/01.str.20.9.1190

Cited by 228 publications

(146 citation statements)

References 20 publications

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“…25,26 Moreover, we found an interrelationship between impaired mobility (SSS of the legs) and depressive symptoms (rϭϪ0.3, Pϭ0.001), a result in agreement with other studies (eg, the Sunnybrook Stroke Study 25 ). However, when impairment of the leg and depressive symptoms were entered in the same model, only the latter was a statistically significant independent predictor of falls.…”

Section: Discussionsupporting

confidence: 91%

Higher Incidence of Falls in Long-Term Stroke Survivors Than in Population Controls

Jørgensen¹,

Engstad²,

Jacobsen³

2002

Stroke

368

298

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Background and Purpose-The incidence of falls among noninstitutionalized individuals with long-standing stroke has not been examined previously, although fractures are more common and the consequences more severe for stroke patients than for elderly people in general. Methods-For 4 months (September to December 1998), we followed 111 home-living patients who had suffered a stroke a mean of 10 years previously and 143 control subjects randomly selected from the same municipality, matched with respect to age and sex. Falls were registered daily by use of "fall calendars." Before the fall registration period, information about morbidity, use of medication, and activities of daily living had been registered. Height, weight, vision, blood pressure, motor function, and body sway had been measured, and depressive symptoms as well as cognitive function had been assessed. Results-During follow-up, 23% of the patients and 11% of the control subjects fell once or more, and the risk of falling at least once was more than twice as high for the patients with stroke, when controlled for potential confounders (relative riskϭ2.2; 95% CI, 1.1 to 4.3). Among the stroke patients, depressive symptomatology predicted falls, and the relative risk for falling increased by 1.5 per standard deviation increase in the depression score. Conclusions-We conclude that falls are more frequent among noninstitutionalized long-term stroke survivors than among community control subjects and that the risk of falling and depressive symptoms are related in stroke patients. (Stroke. 2002;33:542-547.)

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Section: Discussionsupporting

confidence: 91%

Higher Incidence of Falls in Long-Term Stroke Survivors Than in Population Controls

Jørgensen¹,

Engstad²,

Jacobsen³

2002

Stroke

368

298

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“…It impairs the rehabilitation process and, therefore, the functional recovery of patients [19,20]. The MADRS is particularly sensitive to treatment effects [15] and it has been shown to be the best examiner rating scale for assessing depressive symptoms in elderly stroke patients [21]. Whether the improvement in depressive symptoms in the present patients is an effect of improved nocturnal oxygenation, a decreased number of nocturnal arousals, or normalization of cerebral haemodynamics, cannot be determined from this study.…”

Section: Discussionmentioning

confidence: 87%

Nasal continuous positive airway pressure in stroke patients with sleep apnoea: a randomized treatment study

et al. 2001

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The authors have investigated whether treatment of sleep apnoea with nasal continuous positive airway pressure (nCPAP) improves depressive symptoms, personal activities of daily living (ADL), cognitive functioning and delirium in patients that have suffered a stroke.Sixty-three patients consecutively admitted to a stroke rehabilitation unit 2–4 weeks after a stroke, with an apnoea/hypopnoea index ≥15, were randomized to either nCPAP treatment (n=33) or a control group (n=30). Four patients dropped out after randomization. Both groups were assessed at baseline and after 7 and 28 nights using the Montgomery-Åsberg Depression Rating Scale (MADRS), Barthel-ADL index, and the Mini-Mental State Examination (MMSE) scale.Compared to the control group, depressive symptoms (MADRS total score) improved in patients randomized to nCPAP treatment (p=0.004). No significant treatment effect was found with regard to delirium, MMSE or Barthel-ADL index. Delirium and low cognitive level (MMSE score) explained poor compliance with nCPAP.Depressive symptoms are reduced through nasal continuous positive airway pressure treatment in patients with severe stroke and sleep apnoea. Compliance with nasal continuous positive airway pressure treatment is a problem in stroke patients, especially when delirium and severe cognitive impairment occur.

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“…Internal consistency (alpha) has been reported as .88 for depressed patients and .93 for non-depressed patients [41], and as .84 for a previous Australian community sample [42]. The ZSDS has been shown to be superior to the MMPI Depression Scale and the Beck Depression Inventory for assessing depression in male psychiatric inpatients [41] and has sensitivity of 93% in predicting depression validated via clinical interview [43]. ZSDS raw scores of 40 or above indicate the presence of "clinically significant depression" [44, p. 335] and raw scores were used in this study.…”

Section: Materials and Proceduresmentioning

confidence: 97%

A comparison of a single genetic factor, two stress factors, and one psychosocial coping factor as predictors of depression in an Australian community sample.

Sharpley¹,

Palanisamy²,

Metcalf³

et al. 2014

Arch Psych Psych

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SummaryAim. Although both have shown significant effects upon depression in clinical samples, no direct comparison has been reported of the relative power of psychological resilience and the short form of the serotonin transporter gene 5-HTTLPR as predictors of depression in a community sample. material and methods. In a sample set by a priori power analysis, 67 adult females and 59 adult males were used to enable a comparison between a single genetic factor, childhood stressors, recent stressors, psychological resilience and depression. Results. None of genotype, childhood or recent stressors was significantly associated with depression scores, but resilience was a significant inverse predictor of depression scores and also of the presence of clinically significant depression. discussion. These data suggest that measures of an individual's ability to resist or recover from stress may be useful in assessing vulnerability to depression when used with 'at risk' individuals in everyday practice. depression / genes / resilience / stressors / distal / proximalAlthough often seen as being of potential major benefit to clinical treatment settings, the search for a unique and comprehensive genetic biomarker of depression has not been clearly successful as yet [1][2][3] with a recent mega-analysis of 1.2 million single-nucleotide polymorphisms failing to identify robust and replicable findings for any specific genetic factor [4]. Instead, a great deal of recent research has focussed upon the interaction of genes and environment via the serotonin transporter 5-HTTLPR plus the individual's response to various stressors [5][6][7]. The short (ss) form of the 5-HTTLPR has been implicated in studies of affective disorders [8] and in depression among individuals who have experienced distal major stressful life events such as childhood adversity, as well as more recent proximal major stressors from financial, relationship, and occupational sources. This led Karg and colleagues [9] to report that, from a meta-analysis of 54 studies, there was "strong evidence" (p. 444) of the ss allele of the 5-HTTLPR being as- Archives of Psychiatry and Psychotherapy, 2014; 4 : 15-26 sociated with an increased risk of individuals developing depression following distal (childhood) major stressors, major medical conditions and (less robust but still statistically significant) more recent proximal stressors. Those initial findings were recently confirmed by a further meta-analysis of 81 studies [10].However, when considering the applicability of these findings to screening for individuals in clinical practice who are at risk of developing major depression, it is worthy of note that 22 of the 54 studies that Karg et al. (2011) included in their meta-analysis reported data that were "positive" (i.e., that carriers of the ss allele were significantly more likely to have higher depression than carriers of other alleles),13 reported data that were "partially positive", 15 reported no association between the ss, stress and depression, and a further 6 ...

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Comparison of six depression rating scales in geriatric stroke patients.

Cited by 228 publications

References 20 publications

Higher Incidence of Falls in Long-Term Stroke Survivors Than in Population Controls

Higher Incidence of Falls in Long-Term Stroke Survivors Than in Population Controls

Nasal continuous positive airway pressure in stroke patients with sleep apnoea: a randomized treatment study

A comparison of a single genetic factor, two stress factors, and one psychosocial coping factor as predictors of depression in an Australian community sample.

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