Comparison of procedures for determination of copper and zinc in serum by atomic absorption spectroscopy

Taylor, A. H.; Bryant, T. N.

doi:10.1016/0009-8981(81)90304-1

Cited by 33 publications

(13 citation statements)

References 3 publications

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“…Serum zinc was estimated in all patients both at the beginning of the trial (baseline) and 1 month after the cessation of the treatment using the atomic absorption method 20 …”

Section: Methodsmentioning

confidence: 99%

Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial

2002

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“…Serum zinc was estimated in all patients both at the beginning of the trial (baseline) and 1 month after the cessation of the treatment using the atomic absorption method 20 …”

Section: Methodsmentioning

confidence: 99%

Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial

2002

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“…Zinc (Zn) and copper (Cu) were determined by the method of Taylor and Bryant [28] using atomic absorption spectrometer (AAS 800, Perkin Elmer, Shelton, CT, USA); 1 mL of plasma placed in a test tube was diluted to 10 times with deionized water. The test tube was placed in the auto sampler carousel after mild shaking.…”

Section: Estimation Of Micronutrientsmentioning

confidence: 99%

Dose‐response effect of ellagic acid on circulatory antioxidants and lipids during alcohol‐induced toxicity in experimental rats

Nagarajan

Sudheer

Menon³

2007

Fundamemntal Clinical Pharma

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Ellagic acid (EA) is a naturally occurring polyphenolic compound that exhibits antioxidative, anti-inflammatory, anti-hyperlipidaemic and anticarcinogenic activities in a wide range of assays both in vitro and in vivo. It occurs in various foods such as strawberries, grapes, walnuts, etc. The aim of this study was to assess the effect of ellagic acid on alcohol-induced changes in the circulatory antioxidative status, micronutrients and lipid levels in a dose-dependent fashion. Female albino Wistar rats weighing 150-170 g were used to assess the effects of EA against alcohol-induced damage. Three different concentrations of EA (30, 60 and 90 mg/kg body weight) were tested against 20% alcohol via intragastric administration. At the end of the experimental duration of 45 days, we evaluated endogenous antioxidants: both enzymatic (superoxide dismutase, catalase and glutathione peroxidase) and non-enzymatic (vitamin C and E, and reduced glutathione) status, micronutrients, viz. copper and zinc, and lipids: cholesterol, triglycerides, free fatty acids and phospholipids in the circulation. The body weight gain of both alcohol-fed rats and EA-treated rats were also inferred. EA significantly inhibits alcohol-induced toxicity by improving body weight, restoring antioxidant status, modulating micronutrients and attenuating the lipid levels in the circulation. The greatest inhibitory effect was observed with 60 mg/kg body weight of EA in all the biochemical assessments. The results support the hypothesis that EA at the concentration of 60 mg/kg body weight decreases the intensity of alcohol-induced toxicity and could be developed as a potential drug for alcohol abuse in the near future.

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“…23 Copper and zinc were determined by atomic absorption spectrometry (AAnalyst 800, PerkinElmer Instruments, Norwalk, CT). 24 Serum ferritin was assayed by enzyme-linked immunosorbent assay. 25…”

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confidence: 99%

Inhibition of Nicotine-Induced Toxicity by Curcumin and Curcumin Analog: A Comparative Study

Kalpana

Menon

2004

Journal of Medicinal Food

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The present study was undertaken to evaluate the effects of curcumin and curcumin analog on blood oxidant-antioxidant status during nicotine-induced toxicity in male Wistar rats. Lung toxicity was induced by subcutaneous injection of nicotine at a dose of 2.5 mg/kg of body weight (5 days a week, for 22 weeks). The enhanced circulatory lipid peroxides in nicotine-treated rats was accompanied by a significant decrease in the levels of ascorbic acid, vitamin E, reduced glutathione, glutathione peroxidase, superoxide dismutase, and catalase. There was a reduction in the levels of zinc with an elevation of copper and ferritin in nicotine-treated rats. Administration of curcumin and curcumin analog significantly lowered the lipid peroxidation and enhanced the antioxidant status with modulation in the levels of zinc, copper, and ferritin. However, the effect was more significant in curcumin analog-treated rats than in curcumin-treated rats. The results of the present study suggest that curcumin and curcumin analog exert their protective effects by modulating the extent of lipid peroxidation and enhancing the antioxidant status.

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Comparison of procedures for determination of copper and zinc in serum by atomic absorption spectroscopy

Cited by 33 publications

References 3 publications

Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial

Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial

Dose‐response effect of ellagic acid on circulatory antioxidants and lipids during alcohol‐induced toxicity in experimental rats

Inhibition of Nicotine-Induced Toxicity by Curcumin and Curcumin Analog: A Comparative Study

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